Epigenetics & Nuclear Signaling Antibodies 4
Anti-ELF1 Antibody (CAB6904)
- SKU:
- CAB6904
- Product Type:
- Antibody
- Reactivity:
- Human
- Host Species:
- Rabbit
- Isotype:
- IgG
- Antibody Type:
- Polyclonal Antibody
- Research Area:
- Epigenetics and Nuclear Signaling
Description
Antibody Name: | Anti-ELF1 Antibody |
Antibody SKU: | CAB6904 |
Antibody Size: | 20uL, 50uL, 100uL |
Application: | IF |
Reactivity: | Human |
Host Species: | Rabbit |
Immunogen: | Recombinant fusion protein containing a sequence corresponding to amino acids 1-210 of human ELF1 (NP_758961.1). |
Application: | IF |
Recommended Dilution: | IF 1:50 - 1:100 |
Reactivity: | Human |
Positive Samples: |
Immunogen: | Recombinant fusion protein containing a sequence corresponding to amino acids 1-210 of human ELF1 (NP_758961.1). |
Purification Method: | Affinity purification |
Storage Buffer: | Store at -20'C. Avoid freeze / thaw cycles. Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3. |
Isotype: | IgG |
Sequence: | MAAV VQQN DLVF EFAS NVME DERQ LGDP AIFP AVIV EHVP GADI LNSY AGLA CVEE PNDM ITES SLDV AEEE IIDD DDDD ITLT VEAS CHDG DETI ETIE AAEA LLNM DSPG PMLD EKRI NNNI FSSP EDDM VVAP VTHV SVTL DGIP EVME TQQV QEKY ADSP GASS PEQP KRKK GRKT KPPR PDSP ATTP NISV KKKN KDGK GNTI YL |
Gene ID: | 1997 |
Uniprot: | P32519 |
Cellular Location: | Nucleus |
Calculated MW: | 64kDa/67kDa |
Observed MW: |
Synonyms: | ELF1, EFTUD1, RIA1 |
Background: | This gene encodes an E26 transformation-specific related transcription factor. The encoded protein is primarily expressed in lymphoid cells and acts as both an enhancer and a repressor to regulate transcription of various genes. Alternative splicing results in multiple transcript variants. |
UniProt Protein Function: | Elf-1: Transcription factor that activates the LYN and BLK promoters. Appears to be required for the T-cell-receptor-mediated trans activation of HIV-2 gene expression. Binds specifically to two purine-rich motifs in the HIV-2 enhancer. Belongs to the ETS family. |
UniProt Protein Details: | Protein type:DNA-binding; Transcription factor Chromosomal Location of Human Ortholog: 13q13 Cellular Component: nucleoplasm; nucleus Molecular Function:protein binding; transcription factor activity Biological Process: transcription from RNA polymerase II promoter; positive regulation of transcription, DNA-dependent; negative regulation of T cell receptor signaling pathway; positive regulation of transcription from RNA polymerase II promoter; cell differentiation; regulation of cytokine production |
NCBI Summary: | This gene encodes an E26 transformation-specific related transcription factor. The encoded protein is primarily expressed in lymphoid cells and acts as both an enhancer and a repressor to regulate transcription of various genes. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Feb 2009] |
UniProt Code: | P32519 |
NCBI GenInfo Identifier: | 212288097 |
NCBI Gene ID: | 1997 |
NCBI Accession: | P32519.2 |
UniProt Secondary Accession: | P32519,Q8N6F6, Q9UDE1, B4E2I5, E9PDQ9, |
UniProt Related Accession: | P32519 |
Molecular Weight: | 64,929 Da |
NCBI Full Name: | ETS-related transcription factor Elf-1 |
NCBI Synonym Full Names: | E74-like factor 1 (ets domain transcription factor) |
NCBI Official Symbol: | ELF1 |
NCBI Protein Information: | ETS-related transcription factor Elf-1 |
UniProt Protein Name: | ETS-related transcription factor Elf-1 |
UniProt Synonym Protein Names: | E74-like factor 1 |
Protein Family: | ETS-related transcription factor |
UniProt Gene Name: | ELF1 |
UniProt Entry Name: | ELF1_HUMAN |
Immunofluorescence analysis of A549 cells using ELF1 antibody (CAB6904). Blue: DAPI for nuclear staining. |
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