Epigenetics & Nuclear Signaling Antibodies 3
Anti-EIF5A2 Antibody (CAB4864)
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- SKU:
- CAB4864
- Product Type:
- Antibody
- Antibody Type:
- Polyclonal Antibody
- Reactivity:
- Human
- Reactivity:
- Mouse
- Reactivity:
- Rat
- Host Species:
- Rabbit
- Isotype:
- IgG
- Synonyms:
- EIF5A2
- Synonyms:
- EIF-5A2
- Synonyms:
- eIF5AII
- Research Area:
- Epigenetics and Nuclear Signaling
Description
| Product Name: | EIF5A2 Rabbit pAb |
| Product Code: | CAB4864 |
| Size: | 20uL, 50uL, 100uL |
| Synonyms: | EIF5A2, EIF-5A2, eIF5AII |
| Applications: | WB |
| Reactivity: | Human, Mouse, Rat |
| Host Species: | Rabbit |
| Immunogen: | Recombinant fusion protein containing a sequence corresponding to amino acids 1-153 of human EIF5A2 (NP_065123.1). |
| Applications: | WB |
| Recommended Dilutions: | WB 1:200 - 1:2000 |
| Reactivity: | Human, Mouse, Rat |
| Positive Samples: | U-87MG, SKOV3, SW480, THP-1, Mouse lung, Mouse brain, Mouse spleen, Rat lung |
| Immunogen: | Recombinant fusion protein containing a sequence corresponding to amino acids 1-153 of human EIF5A2 (NP_065123.1). |
| Purification Method: | Affinity purification |
| Storage: | Store at -20°C. Avoid freeze / thaw cycles. Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3. |
| Isotype: | IgG |
| Sequence: | MADE IDFT TGDA GASS TYPM QCSA LRKN GFVV LKGR PCKI VEMS TSKT GKHG HAKV HLVG IDIF TGKK YEDI CPST HNMD VPNI KRND YQLI CIQD GYLS LLTE TGEV REDL KLPE GELG KEIE GKYN AGED VQVS VMCA MSEE YAVA IKPC K |
| Gene ID: | 56648 |
| Uniprot: | Q9GZV4 |
| Cellular Location: | Cytoplasm, Cytoplasmic side, Endoplasmic reticulum membrane, Nucleus, Peripheral membrane protein, nuclear pore complex |
| Calculated MW: | 16kDa |
| Observed MW: | 17kDa |
| UniProt Protein Function: | EIF5A2: mRNA-binding protein involved in translation elongation. Has an important function at the level of mRNA turnover, probably acting downstream of decapping. Involved in actin dynamics and cell cycle progression, mRNA decay and probably in a pathway involved in stress response and maintenance of cell wall integrity. Functions as a regulator of apoptosis. Mediates effects of polyamines on neuronal process extension and survival. May play an important role in brain development and function, and in skeletal muscle stem cell differentiation. Belongs to the eIF-5A family. |
| UniProt Protein Details: | Chromosomal Location of Human Ortholog: 3q26.2 Cellular Component: cytosol; intracellular membrane-bound organelle Molecular Function:protein binding Biological Process: hypusine biosynthetic process from peptidyl-lysine; positive regulation of cell proliferation |
| UniProt Code: | Q9GZV4 |
| NCBI GenInfo Identifier: | 74762725 |
| NCBI Gene ID: | 56648 |
| NCBI Accession: | Q9GZV4.3 |
| UniProt Secondary Accession: | Q9GZV4,B2R4V5, |
| UniProt Related Accession: | Q9GZV4 |
| Molecular Weight: | 16,793 Da |
| NCBI Full Name: | Eukaryotic translation initiation factor 5A-2 |
| NCBI Synonym Full Names: | eukaryotic translation initiation factor 5A2 |
| NCBI Official Symbol: | EIF5A2 |
| NCBI Official Synonym Symbols: | EIF-5A2; eIF5AII |
| NCBI Protein Information: | eukaryotic translation initiation factor 5A-2 |
| UniProt Protein Name: | Eukaryotic translation initiation factor 5A-2 |
| UniProt Synonym Protein Names: | Eukaryotic initiation factor 5A isoform 2 |
| UniProt Gene Name: | EIF5A2 |
| UniProt Entry Name: | IF5A2_HUMAN |
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