Cell Biology Antibodies 5

Anti-EIF4ENIF1 Antibody (CAB15175)

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SKU:
CAB15175
Product Type:
Antibody
Reactivity:
Human
Reactivity:
Mouse
Host Species:
Rabbit
Isotype:
IgG
Antibody Type:
Polyclonal Antibody
Research Area:
Cell Biology

Description

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Antibody Name:Anti-EIF4ENIF1 Antibody
Antibody SKU:CAB15175
Antibody Size:20uL, 50uL, 100uL
Application:WB
Reactivity:Human, Mouse
Host Species:Rabbit
Immunogen:A synthetic peptide corresponding to a sequence within amino acids 150-250 of human EIF4ENIF1 (NP_001157973.1).
Application:WB
Recommended Dilution:WB 1:500 - 1:2000
Reactivity:Human, Mouse
Positive Samples:U-251MG, HeLa, HT-29, LO2
Immunogen:A synthetic peptide corresponding to a sequence within amino acids 150-250 of human EIF4ENIF1 (NP_001157973.1).
Purification Method:Affinity purification
Storage Buffer:Store at -20'C. Avoid freeze / thaw cycles. Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3.
Isotype:IgG
Sequence:LGGR RIGS GRII SART FEKD HRLS DKDL RDLR DRDR ERDF KDKR FRRE FGDS KRVF GERR RNDS YTEE EPEW FSAG PTSQ SETI ELTG FDDK ILEE DHKG R
Gene ID:56478
Uniprot:Q9NRA8
Cellular Location:Cytoplasm, Nucleus, Nucleus speckle, PML body
Calculated MW:88kDa/108kDa
Observed MW:178kDa
Synonyms:EIF4ENIF1, 4E-T, Clast4
Background:The protein encoded by this gene is a nucleocytoplasmic shuttle protein for the translation initiation factor eIF4E. This shuttle protein interacts with the importin alpha-beta complex to mediate nuclear import of eIF4E. It is predominantly cytoplasmic; its own nuclear import is regulated by a nuclear localization signal and nuclear export signals. Multiple transcript variants encoding different isoforms have been found for this gene.
UniProt Protein Function:Nucleoplasmic shuttling protein. Mediates the nuclear import of EIF4E by a piggy-back mechanism.
NCBI Summary:The protein encoded by this gene is a nucleocytoplasmic shuttle protein for the translation initiation factor eIF4E. This shuttle protein interacts with the importin alpha-beta complex to mediate nuclear import of eIF4E. It is predominantly cytoplasmic; its own nuclear import is regulated by a nuclear localization signal and nuclear export signals. Multiple transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Aug 2009]
UniProt Code:Q9NRA8
NCBI GenInfo Identifier:22095430
NCBI Gene ID:56478
NCBI Accession:Q9NRA8.2
UniProt Secondary Accession:Q9NRA8,Q8NCF2, Q9H708, B1AKL2, B1AKL3, B2RBF1,
UniProt Related Accession:Q9NRA8
Molecular Weight:108,329 Da
NCBI Full Name:Eukaryotic translation initiation factor 4E transporter
NCBI Synonym Full Names:eukaryotic translation initiation factor 4E nuclear import factor 1
NCBI Official Symbol:EIF4ENIF1  
NCBI Official Synonym Symbols:4E-T; Clast4  
NCBI Protein Information:eukaryotic translation initiation factor 4E transporter
UniProt Protein Name:Eukaryotic translation initiation factor 4E transporter
UniProt Synonym Protein Names:Eukaryotic translation initiation factor 4E nuclear import factor 1
Protein Family:Eukaryotic translation initiation factor 4E transporter
UniProt Gene Name:EIF4ENIF1  
UniProt Entry Name:4ET_HUMAN
Anti-EIF4ENIF1 Antibody (CAB15175)Western blot analysis of extracts of various cell lines, using EIF4ENIF1 antibody (CAB15175) at 1:1000 dilution. Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) (CABS014) at 1:10000 dilution. Lysates/proteins: 25ug per lane. Blocking buffer: 3% nonfat dry milk in TBST. Detection: ECL Basic Kit (RM00020). Exposure time: 3s.
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