Anti-eIF3e Antibody (CAB3431)
- SKU:
- CAB3431
- Product Type:
- Antibody
- Antibody Type:
- Monoclonal Antibody
- Reactivity:
- Human
- Reactivity:
- Mouse
- Reactivity:
- Rat
- Host Species:
- Rabbit
- Isotype:
- IgG
- Synonyms:
- EIF3-P48
- Synonyms:
- EIF3S6
- Synonyms:
- INT6
- Synonyms:
- eIF3-p46
- Research Area:
- Metabolism
Description
| Product Name: | eIF3e Rabbit mAb |
| Product Code: | CAB3431 |
| Size: | 20uL, 50uL, 100uL |
| Synonyms: | EIF3-P48, EIF3S6, INT6, eIF3-p46 |
| Applications: | WB, IHC |
| Reactivity: | Human, Mouse, Rat |
| Host Species: | Rabbit |
| Immunogen: | A synthesized peptide derived from human eIF3e |
| Applications: | WB, IHC |
| Recommended Dilutions: | WB 1:500 - 1:2000 IHC 1:50 - 1:200 |
| Reactivity: | Human, Mouse, Rat |
| Positive Samples: | HeLa, 293T, Jurkat, Mouse lung, Mouse testis, Rat lung, Rat testis |
| Immunogen: | A synthesized peptide derived from human eIF3e |
| Purification Method: | Affinity purification |
| Storage: | Store at -20°C. Avoid freeze / thaw cycles. Buffer: PBS with 0.02% sodium azide, 0.05% BSA, 50% glycerol, pH7.3. |
| Isotype: | IgG |
| Sequence: | Email for sequence |
| Gene ID: | 3646 |
| Uniprot: | P60228 |
| Cellular Location: | Cytoplasm, Nucleus, PML body |
| Calculated MW: | 45kDa |
| Observed MW: | 48kDa |
| UniProt Protein Function: | EIF3E: eukaryotic translation initiation factor 3 subunit 2. Binds to the 40S ribosome and promotes the binding of methionyl-tRNAi and mRNA. eIF-3 is composed of at least 12 different subunits. Phosphorylated by TGF-beta type II receptor. |
| UniProt Protein Details: | Protein type:Translation initiation; Translation Chromosomal Location of Human Ortholog: 8q22-q23 Cellular Component: eukaryotic translation initiation factor 3 complex; nucleoplasm; PML body; membrane; cytoplasm; cytosol; chromatin; nucleus Molecular Function:protein binding; translation initiation factor activity; protein N-terminus binding Biological Process: negative regulation of translational initiation; cellular protein metabolic process; translation; mRNA catabolic process, nonsense-mediated decay; translational initiation; gene expression; formation of translation preinitiation complex; regulation of translational initiation |
| UniProt Code: | P60228 |
| NCBI GenInfo Identifier: | 41019126 |
| NCBI Gene ID: | 3646 |
| NCBI Accession: | P60228.1 |
| UniProt Secondary Accession: | P60228,O43902, Q64058, Q64059, Q64252, Q6FG33, Q8WVK4 |
| UniProt Related Accession: | P60228 |
| Molecular Weight: | 52,221 Da |
| NCBI Full Name: | Eukaryotic translation initiation factor 3 subunit E |
| NCBI Synonym Full Names: | eukaryotic translation initiation factor 3, subunit E |
| NCBI Official Symbol: | EIF3E |
| NCBI Official Synonym Symbols: | INT6; EIF3S6; EIF3-P48; eIF3-p46 |
| NCBI Protein Information: | eukaryotic translation initiation factor 3 subunit E; eIF-3 p48; mammary tumor-associated protein INT6; viral integration site protein INT-6 homolog; eukaryotic translation initiation factor 3 subunit 6; murine mammary tumor integration site 6 (oncogene homolog); eukaryotic translation initiation factor 3, subunit 6 48kDa |
| UniProt Protein Name: | Eukaryotic translation initiation factor 3 subunit E |
| UniProt Synonym Protein Names: | Eukaryotic translation initiation factor 3 subunit 6; Viral integration site protein INT-6 homolog; eIF-3 p48 |
| UniProt Gene Name: | EIF3E |
| UniProt Entry Name: | EIF3E_HUMAN |
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