Cell Biology Antibodies 16
Anti-Eif2ak2 Antibody (CAB13583)
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- SKU:
- CAB13583
- Product Type:
- Antibody
- Reactivity:
- Human
- Reactivity:
- Rat
- Host Species:
- Rabbit
- Isotype:
- IgG
- Antibody Type:
- Polyclonal Antibody
- Research Area:
- Cell Biology
Description
| Antibody Name: | Anti-Eif2ak2 Antibody |
| Antibody SKU: | CAB13583 |
| Antibody Size: | 20uL, 50uL, 100uL |
| Application: | IHC |
| Reactivity: | Human, Rat |
| Host Species: | Rabbit |
| Immunogen: | Recombinant protein of mouse Eif2ak2 |
| Application: | IHC |
| Recommended Dilution: | IHC 1:50 - 1:200 |
| Reactivity: | Human, Rat |
| Positive Samples: |
| Immunogen: | Recombinant protein of mouse Eif2ak2 |
| Purification Method: | Affinity purification |
| Storage Buffer: | Store at -20'C. Avoid freeze / thaw cycles. Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3. |
| Isotype: | IgG |
| Sequence: | Email for sequence |
| Gene ID: | 19106 |
| Uniprot: | |
| Cellular Location: | Cytoplasm, Nucleus, perinuclear region |
| Calculated MW: | 58kDa |
| Observed MW: |
| Synonyms: | EIF2AK2, EIF2AK1, PKR, PPP1R83, PRKR, Eif2ak2 |
| Background: | The protein encoded by this gene is a serine/threonine protein kinase that is activated by autophosphorylation after binding to dsRNA. The activated form of the encoded protein can phosphorylate translation initiation factor EIF2S1, which in turn inhibits protein synthesis. This protein is also activated by manganese ions and heparin. Three transcript variants encoding two different isoforms have been found for this gene. |
 | Immunohistochemistry of paraffin-embedded rat brain using Eif2ak2 antibody (CAB13583) at dilution of 1:200 (40x lens). |
 | Immunohistochemistry of paraffin-embedded human lung cancer using Eif2ak2 antibody (CAB13583) at dilution of 1:200 (40x lens). |
 | Immunohistochemistry of paraffin-embedded human liver cancer using Eif2ak2 antibody (CAB13583) at dilution of 1:200 (40x lens). |
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