Anti-EHD1 Antibody (CAB3496)
- SKU:
- CAB3496
- Product Type:
- Antibody
- Antibody Type:
- Monoclonal Antibody
- Reactivity:
- Human
- Reactivity:
- Mouse
- Reactivity:
- Rat
- Host Species:
- Rabbit
- Isotype:
- IgG
- Synonyms:
- H-PAST
- Synonyms:
- HPAST1
- Synonyms:
- PAST
- Synonyms:
- PAST1
- Research Area:
- Cell Biology
Description
| Product Name: | EHD1 Rabbit mAb |
| Product Code: | CAB3496 |
| Size: | 20uL, 50uL, 100uL |
| Synonyms: | H-PAST, HPAST1, PAST, PAST1 |
| Applications: | WB, IHC |
| Reactivity: | Human, Mouse, Rat |
| Host Species: | Rabbit |
| Immunogen: | A synthesized peptide derived from human EHD1 |
| Applications: | WB, IHC |
| Recommended Dilutions: | WB 1:500 - 1:2000 IHC 1:50 - 1:200 |
| Reactivity: | Human, Mouse, Rat |
| Positive Samples: | HeLa, THP-1, U-251MG, Mouse liver, Mouse brain, Mouse spleen, Rat lung, Rat testis, Rat kidney |
| Immunogen: | A synthesized peptide derived from human EHD1 |
| Purification Method: | Affinity purification |
| Storage: | Store at -20°C. Avoid freeze / thaw cycles. Buffer: PBS with 0.02% sodium azide, 0.05% BSA, 50% glycerol, pH7.3. |
| Isotype: | IgG |
| Sequence: | Email for sequence |
| Gene ID: | 10938 |
| Uniprot: | Q9H4M9 |
| Cellular Location: | Cell membrane, Cell projection, Cytoplasmic side, Early endosome membrane, Peripheral membrane protein, Recycling endosome membrane, cilium membrane |
| Calculated MW: | 61kDa |
| Observed MW: | 61kDa |
| UniProt Protein Function: | EHD1: Acts in early endocytic membrane fusion and membrane trafficking of recycling endosomes. |
| UniProt Protein Details: | Protein type:Vesicle; Calcium-binding Chromosomal Location of Human Ortholog: 11q13 Cellular Component: early endosome membrane; endosome membrane; lipid particle; membrane; plasma membrane; recycling endosome membrane Molecular Function:ATP binding; calcium ion binding; GTP binding; protein binding; Rab GTPase binding Biological Process: blood coagulation; cholesterol homeostasis; cilium biogenesis; endocytic recycling; endocytosis; intracellular protein transport; neurite development; protein homooligomerization |
| NCBI Summary: | This gene belongs to a highly conserved gene family encoding EPS15 homology (EH) domain-containing proteins. The protein-binding EH domain was first noted in EPS15, a substrate for the epidermal growth factor receptor. The EH domain has been shown to be an important motif in proteins involved in protein-protein interactions and in intracellular sorting. The protein encoded by this gene is thought to play a role in the endocytosis of IGF1 receptors. Alternatively spliced transcript variants have been found for this gene. [provided by RefSeq, Sep 2013] |
| UniProt Code: | Q9H4M9 |
| NCBI GenInfo Identifier: | 18202945 |
| NCBI Gene ID: | 10938 |
| NCBI Accession: | Q9H4M9.2 |
| UniProt Secondary Accession: | Q9H4M9,O14611, Q2M3Q4, Q9UNR3, |
| UniProt Related Accession: | Q9H4M9 |
| Molecular Weight: | 60,627 Da |
| NCBI Full Name: | EH domain-containing protein 1 |
| NCBI Synonym Full Names: | EH domain containing 1 |
| NCBI Official Symbol: | EHD1 |
| NCBI Official Synonym Symbols: | PAST; PAST1; H-PAST; HPAST1 |
| NCBI Protein Information: | EH domain-containing protein 1 |
| UniProt Protein Name: | EH domain-containing protein 1 |
| UniProt Synonym Protein Names: | PAST homolog 1 |
| Protein Family: | EH domain-containing protein |
| UniProt Gene Name: | EHD1 |
| UniProt Entry Name: | EHD1_HUMAN |
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