Epigenetics & Nuclear Signaling Antibodies 4

Anti-EGR3 Antibody (CAB7669)

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SKU:
CAB7669
Product Type:
Antibody
Reactivity:
Human
Reactivity:
Mouse
Host Species:
Rabbit
Isotype:
IgG
Antibody Type:
Polyclonal Antibody
Research Area:
Epigenetics and Nuclear Signaling

Description

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Antibody Name:Anti-EGR3 Antibody
Antibody SKU:CAB7669
Antibody Size:20uL, 50uL, 100uL
Application:WB
Reactivity:Human, Mouse
Host Species:Rabbit
Immunogen:Recombinant fusion protein containing a sequence corresponding to amino acids 1-250 of human EGR3 (NP_004421.2).
Application:WB
Recommended Dilution:WB 1:500 - 1:2000
Reactivity:Human, Mouse
Positive Samples:SKOV3
Immunogen:Recombinant fusion protein containing a sequence corresponding to amino acids 1-250 of human EGR3 (NP_004421.2).
Purification Method:Affinity purification
Storage Buffer:Store at -20'C. Avoid freeze / thaw cycles. Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3.
Isotype:IgG
Sequence:MTGK LAEK LPVT MSSL LNQL PDNL YPEE IPSA LNLF SGSS DSVV HYNQ MATE NVMD IGLT NEKP NPEL SYSG SFQP APGN KTVT YLGK FAFD SPSN WCQD NIIS LMSA GILG VPPA SGAL STQT STAS MVQP PQGD VEAM YPAL PPYS NCGD LYSE PVSF HDPQ GNPG LAYS PQDY QSAK PALD SNLF PMIP DYNL YHHP NDMG SIPE HKPF QGMD PIRV NPPP ITPL ETIK AFKD KQIH PGFG SLPQ PP
Gene ID:1960
Uniprot:Q06889
Cellular Location:Nucleus
Calculated MW:38kDa/42kDa
Observed MW:43kDa
Synonyms:EGR3, EGR-3, PILOT
Background:This gene encodes a transcriptional regulator that belongs to the EGR family of C2H2-type zinc-finger proteins. It is an immediate-early growth response gene which is induced by mitogenic stimulation. The protein encoded by this gene participates in the transcriptional regulation of genes in controling biological rhythm. It may also play a role in a wide variety of processes including muscle development, lymphocyte development, endothelial cell growth and migration, and neuronal development. Alternative splicing results in multiple transcript variants encoding distinct isoforms.
NCBI Summary:This gene encodes a transcriptional regulator that belongs to the EGR family of C2H2-type zinc-finger proteins. It is an immediate-early growth response gene which is induced by mitogenic stimulation. The protein encoded by this gene participates in the transcriptional regulation of genes in controling biological rhythm. It may also play a role in a wide variety of processes including muscle development, lymphocyte development, endothelial cell growth and migration, and neuronal development. Alternative splicing results in multiple transcript variants encoding distinct isoforms.[provided by RefSeq, Dec 2010]
UniProt Code:Q06889
NCBI GenInfo Identifier:85567704
NCBI Gene ID:1960
NCBI Accession:BC112279
UniProt Related Accession:Q06889
Molecular Weight:44KD
NCBI Full Name:Homo sapiens early growth response 3, mRNA
NCBI Synonym Full Names:early growth response 3
NCBI Official Symbol:EGR3  
NCBI Official Synonym Symbols:EGR-3; PILOT  
NCBI Protein Information:early growth response protein 3
UniProt Protein Name:
Protein Family:Early growth response protein
UniProt Gene Name:
Anti-EGR3 Antibody (CAB7669)Western blot analysis of extracts of SKOV3 cells, using EGR3 antibody (CAB7669) at 1:1000 dilution. Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) (CABS014) at 1:10000 dilution. Lysates/proteins: 25ug per lane. Blocking buffer: 3% nonfat dry milk in TBST. Detection: ECL Enhanced Kit (RM00021). Exposure time: 30s.
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