Cell Cycle Antibodies 2

Anti-Eg5 Antibody (CAB4659)

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SKU:
CAB4659
Product Type:
Antibody
Reactivity:
Human
Host Species:
Rabbit
Isotype:
IgG
Research Area:
Cell Cycle

Description

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Antibody Name:Anti-Eg5 Antibody
Antibody SKU:CAB4659
Antibody Size:20uL, 50uL, 100uL
Application:WB
Reactivity:Human
Host Species:Rabbit
Immunogen:A synthesized peptide derived from human Eg5
Application:WB
Recommended Dilution:WB 1:500 - 1:2000
Reactivity:Human
Positive Samples:A-549, MCF7
Immunogen:A synthesized peptide derived from human Eg5
Purification Method:Affinity purification
Storage Buffer:Store at -20'C. Avoid freeze / thaw cycles. Buffer: PBS with 0.02% sodium azide, 0.05% BSA, 50% glycerol, pH7.3.
Isotype:IgG
Sequence:Email for sequence
Gene ID:3832
Uniprot:P52732
Cellular Location:
Calculated MW:119kDa
Observed MW:130KDa
Synonyms:EG5, HKSP, KNSL1, MCLMR, TRIP5
Background:This gene encodes a motor protein that belongs to the kinesin-like protein family. Members of this protein family are known to be involved in various kinds of spindle dynamics. The function of this gene product includes chromosome positioning, centrosome separation and establishing a bipolar spindle during cell mitosis. [provided by RefSeq, Jul 2008]
UniProt Protein Function:KIF11: a cytoskeletal protein that belongs to the kinesin-like protein family. BimC subfamily. Interacts with the thyroid hormone receptor in the presence of thyroid hormone. Plays a role in chromosome positioning, centrosome separation and establishing a bipolar spindle during cell mitosis. Phosphorylation regulates its association with the spindle apparatus.
UniProt Protein Details:

Protein type:Motor; Microtubule-binding

Chromosomal Location of Human Ortholog: 10q24.1

Cellular Component: spindle pole; kinesin complex; microtubule; membrane; spindle microtubule; cytoplasm; spindle; cytosol

Molecular Function:plus-end-directed microtubule motor activity; microtubule binding; ATPase activity; protein complex binding; microtubule motor activity; protein kinase binding; ATP binding

Biological Process: mitosis; mitotic centrosome separation; mitotic spindle organization and biogenesis; cell division; metabolic process; regulation of mitotic centrosome separation; antigen processing and presentation of exogenous peptide antigen via MHC class II; blood coagulation; spindle organization and biogenesis; microtubule-based movement; chromosome segregation

Disease: Microcephaly With Or Without Chorioretinopathy, Lymphedema, Or Mental Retardation

NCBI Summary:This gene encodes a motor protein that belongs to the kinesin-like protein family. Members of this protein family are known to be involved in various kinds of spindle dynamics. The function of this gene product includes chromosome positioning, centrosome separation and establishing a bipolar spindle during cell mitosis. [provided by RefSeq, Jul 2008]
UniProt Code:P52732
NCBI GenInfo Identifier:116242604
NCBI Gene ID:3832
NCBI Accession:P52732.2
UniProt Secondary Accession:P52732,Q15716, Q5VWX0, A0AV49, B2RMV3,
UniProt Related Accession:P52732
Molecular Weight:119,159 Da
NCBI Full Name:Kinesin-like protein KIF11
NCBI Synonym Full Names:kinesin family member 11
NCBI Official Symbol:KIF11  
NCBI Official Synonym Symbols:EG5; HKSP; KNSL1; MCLMR; TRIP5  
NCBI Protein Information:kinesin-like protein KIF11; TR-interacting protein 5; TRIP-5; kinesin-like protein 1; kinesin-like spindle protein HKSP; kinesin-related motor protein Eg5; thyroid receptor-interacting protein 5
UniProt Protein Name:Kinesin-like protein KIF11
UniProt Synonym Protein Names:Kinesin-like protein 1; Kinesin-like spindle protein HKSP; Kinesin-related motor protein Eg5; Thyroid receptor-interacting protein 5; TR-interacting protein 5; TRIP-5
Protein Family:Kinesin-like protein
UniProt Gene Name:KIF11  
UniProt Entry Name:KIF11_HUMAN
Anti-Eg5 Antibody (CAB4659)Western blot - Eg5 Rabbit mAb (CAB4659)
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