Signal Transduction Antibodies 2
Anti-EFHD2 Antibody (CAB14926)
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- SKU:
- CAB14926
- Product Type:
- Antibody
- Reactivity:
- Human
- Reactivity:
- Mouse
- Host Species:
- Rabbit
- Isotype:
- IgG
- Antibody Type:
- Polyclonal Antibody
- Research Area:
- Signal Transduction
Description
| Antibody Name: | Anti-EFHD2 Antibody |
| Antibody SKU: | CAB14926 |
| Antibody Size: | 20uL, 50uL, 100uL |
| Application: | WB IHC |
| Reactivity: | Human, Mouse |
| Host Species: | Rabbit |
| Immunogen: | Recombinant fusion protein containing a sequence corresponding to amino acids 1-78 of human EFHD2 (NP_077305.2). |
| Application: | WB IHC |
| Recommended Dilution: | WB 1:500 - 1:2000 IHC 1:50 - 1:200 |
| Reactivity: | Human, Mouse |
| Positive Samples: | Mouse lung |
| Immunogen: | Recombinant fusion protein containing a sequence corresponding to amino acids 1-78 of human EFHD2 (NP_077305.2). |
| Purification Method: | Affinity purification |
| Storage Buffer: | Store at -20'C. Avoid freeze / thaw cycles. Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3. |
| Isotype: | IgG |
| Sequence: | MATD ELAT KLSR RLQM EGEG GGET PEQP GLNG AAAA AAGA PDEA AEAL GSAD CELS AKLL RRAD LNQG IGEP QSPS RR |
| Gene ID: | 79180 |
| Uniprot: | Q96C19 |
| Cellular Location: | Membrane raft |
| Calculated MW: | 26kDa |
| Observed MW: | 27kDa |
| Synonyms: | EFHD2, SWS1 |
| Background: |
| UniProt Protein Function: | EFHD2: May regulate B-cell receptor (BCR)-induced immature and primary B-cell apoptosis. Plays a role as negative regulator of the canonical NF-kappa-B-activating branch. Controls spontaneous apoptosis through the regulation of BCL2L1 abundance. |
| UniProt Protein Details: | Protein type:Calcium-binding Chromosomal Location of Human Ortholog: 1p36.21 Cellular Component: lipid raft Molecular Function:calcium ion binding |
| UniProt Code: | Q96C19 |
| NCBI GenInfo Identifier: | 20149675 |
| NCBI Gene ID: | 79180 |
| NCBI Accession: | NP_077305 |
| UniProt Secondary Accession: | Q96C19,Q9D8Y0, |
| UniProt Related Accession: | Q96C19 |
| Molecular Weight: | 26,697 Da |
| NCBI Full Name: | EF-hand domain-containing protein D2 |
| NCBI Synonym Full Names: | EF-hand domain family, member D2 |
| NCBI Official Symbol: | EFHD2 |
| NCBI Official Synonym Symbols: | SWS1 |
| NCBI Protein Information: | EF-hand domain-containing protein D2; swiprosin 1; swiprosin-1; EF hand domain containing 2; EF hand domain family, member D2 |
| UniProt Protein Name: | EF-hand domain-containing protein D2 |
| UniProt Synonym Protein Names: | Swiprosin-1 |
| Protein Family: | Zinc finger SWIM domain-containing protein |
| UniProt Gene Name: | EFHD2 |
| UniProt Entry Name: | EFHD2_HUMAN |
 | Western blot analysis of extracts of mouse lung, using EFHD2 antibody (CAB14926) at 1:1000 dilution. Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) (CABS014) at 1:10000 dilution. Lysates/proteins: 25ug per lane. Blocking buffer: 3% nonfat dry milk in TBST. Detection: ECL Basic Kit (RM00020). Exposure time: 90s. |
 | Immunohistochemistry of paraffin-embedded human tonsil using EFHD2 antibody (CAB14926) at dilution of 1:150 (40x lens). |
 | Immunohistochemistry of paraffin-embedded human appendix using EFHD2 antibody (CAB14926) at dilution of 1:150 (40x lens). |
 | Immunohistochemistry of paraffin-embedded mouse spleen using EFHD2 antibody (CAB14926) at dilution of 1:150 (40x lens). |
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