Cell Biology Antibodies 9

Anti-EDIL-3 Antibody (CAB4370)

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SKU:
CAB4370
Product Type:
Antibody
Reactivity:
Human
Host Species:
Rabbit
Isotype:
IgG
Research Area:
Cell Biology

Description

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Antibody Name:EDIL3 Rabbit Polyclonal Antibody
Antibody SKU:CAB4370
Antibody Size:20uL, 50uL, 100uL
Application:WB
Reactivity:Human
Host Species:Rabbit
Immunogen:Recombinant fusion protein containing a sequence corresponding to amino acids 60-300 of human EDIL3 (NP_005702.3).
Application:WB
Recommended Dilution:WB 1:1000 - 1:2000
Reactivity:Human
Positive Samples:U-87MG, HeLa, DU145
Immunogen:Recombinant fusion protein containing a sequence corresponding to amino acids 60-300 of human EDIL3 (NP_005702.3).
Purification Method:Affinity purification
Storage Buffer:Store at -20'C. Avoid freeze / thaw cycles. Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3.
Isotype:IgG
Sequence:SSVV EVAS DEEE PTSA GPCT PNPC HNGG TCEI SEAY RGDT FIGY VCKC PRGF NGIH CQHN INEC EVEP CKNG GICT DLVA NYSC ECPG EFMG RNCQ YKCS GPLG IEGG IISN QQIT ASST HRAL FGLQ KWYP YYAR LNKK GLIN AWTA AEND RWPW IQIN LQRK MRVT GVIT QGAK RIGS PEYI KSYK IAYS NDGK TWAM YKVK GTNE DMVF RGNI DNNT PYAN SFTP PIKA QYVR LYPQ V
Gene ID:10085
Uniprot:O43854
Cellular Location:Secreted
Calculated MW:52kDa/53kDa
Observed MW:54kDa
Synonyms:EDIL3, DEL1
Background:The protein encoded by this gene is an integrin ligand. It plays an important role in mediating angiogenesis and may be important in vessel wall remodeling and development. It also influences endothelial cell behavior.
UniProt Protein Function:EDIL3: Promotes adhesion of endothelial cells through interaction with the alpha-v/beta-3 integrin receptor. Inhibits formation of vascular-like structures. May be involved in regulation of vascular morphogenesis of remodeling in embryonic development. 2 isoforms of the human protein are produced by alternative splicing.
UniProt Protein Details:

Protein type:Secreted, signal peptide; Secreted; Cell adhesion

Chromosomal Location of Human Ortholog: 5q14

Cellular Component: vesicle

Molecular Function:integrin binding; calcium ion binding

Biological Process: multicellular organismal development; cell adhesion

NCBI Summary:The protein encoded by this gene is an integrin ligand. It plays an important role in mediating angiogenesis and may be important in vessel wall remodeling and development. It also influences endothelial cell behavior. [provided by RefSeq, Jul 2008]
UniProt Code:O43854
NCBI GenInfo Identifier:41016967
NCBI Gene ID:10085
NCBI Accession:O43854.1
UniProt Secondary Accession:O43854,O43855, Q5D094, Q8N610, B2R763,
UniProt Related Accession:O43854
Molecular Weight:480
NCBI Full Name:EGF-like repeat and discoidin I-like domain-containing protein 3
NCBI Synonym Full Names:EGF-like repeats and discoidin I-like domains 3
NCBI Official Symbol:EDIL3  
NCBI Official Synonym Symbols:DEL1  
NCBI Protein Information:EGF-like repeat and discoidin I-like domain-containing protein 3; integrin-binding protein DEL1; developmental endothelial locus-1; developmentally-regulated endothelial cell locus 1 protein
UniProt Protein Name:EGF-like repeat and discoidin I-like domain-containing protein 3
UniProt Synonym Protein Names:Developmentally-regulated endothelial cell locus 1 protein; Integrin-binding protein DEL1
Protein Family:EGF-like repeat and discoidin I-like domain-containing protein
UniProt Gene Name:EDIL3  
UniProt Entry Name:EDIL3_HUMAN
Anti-EDIL-3 Antibody (CAB4370)Western blot analysis of extracts of various cell lines, using EDIL3 antibody (CAB4370) at 1:1000 dilution. Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) (CABS014) at 1:10000 dilution. Lysates/proteins: 25ug per lane. Blocking buffer: 3% nonfat dry milk in TBST. Detection: ECL Basic Kit (RM00020). Exposure time: 1s.
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