Name: Anti-EDIL-3 Antibody (CAB15772)
Brand: Cell Biology Antibodies 6
SKU: CAB15772
Availability: OutOfStock

Antibody Name:	EDIL3 Rabbit Polyclonal Antibody
Antibody SKU:	CAB15772
Antibody Size:	20uL, 50uL, 100uL
Application:	WB IF
Reactivity:	Human, Mouse
Host Species:	Rabbit
Immunogen:	A synthetic peptide corresponding to a sequence within amino acids 350-450 of human EDIL3 (NP_005702.3).

Application:	WB IF
Recommended Dilution:	WB 1:500 - 1:2000 IF 1:50 - 1:200
Reactivity:	Human, Mouse
Positive Samples:	Mouse lung, Mouse brain

Immunogen:	A synthetic peptide corresponding to a sequence within amino acids 350-450 of human EDIL3 (NP_005702.3).
Purification Method:	Affinity purification
Storage Buffer:	Store at -20'C. Avoid freeze / thaw cycles. Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3.
Isotype:	IgG
Sequence:	TWEP RKAR LDKQ GKVN AWTS GHND QSQW LQVD LLVP TKVT GIIT QGAK DFGH VQFV GSYK LAYS NDGE HWTV YQDE KQRK DKVF QGNF DNDT HRKN VIDP P
Gene ID:	10085
Uniprot:	O43854
Cellular Location:	Secreted
Calculated MW:	52kDa/53kDa
Observed MW:	52kDa

Synonyms:	EDIL3, DEL1
Background:	The protein encoded by this gene is an integrin ligand. It plays an important role in mediating angiogenesis and may be important in vessel wall remodeling and development. It also influences endothelial cell behavior.

UniProt Protein Function:	EDIL3: Promotes adhesion of endothelial cells through interaction with the alpha-v/beta-3 integrin receptor. Inhibits formation of vascular-like structures. May be involved in regulation of vascular morphogenesis of remodeling in embryonic development. 2 isoforms of the human protein are produced by alternative splicing.
UniProt Protein Details:	Protein type:Secreted, signal peptide; Secreted; Cell adhesion Chromosomal Location of Human Ortholog: 5q14 Cellular Component: vesicle Molecular Function:integrin binding; calcium ion binding Biological Process: multicellular organismal development; cell adhesion
NCBI Summary:	The protein encoded by this gene is an integrin ligand. It plays an important role in mediating angiogenesis and may be important in vessel wall remodeling and development. It also influences endothelial cell behavior. [provided by RefSeq, Jul 2008]
UniProt Code:	O43854
NCBI GenInfo Identifier:	41016967
NCBI Gene ID:	10085
NCBI Accession:	O43854.1
UniProt Secondary Accession:	O43854,O43855, Q5D094, Q8N610, B2R763,
UniProt Related Accession:	O43854
Molecular Weight:	480
NCBI Full Name:	EGF-like repeat and discoidin I-like domain-containing protein 3
NCBI Synonym Full Names:	EGF-like repeats and discoidin I-like domains 3
NCBI Official Symbol:	EDIL3
NCBI Official Synonym Symbols:	DEL1
NCBI Protein Information:	EGF-like repeat and discoidin I-like domain-containing protein 3; integrin-binding protein DEL1; developmental endothelial locus-1; developmentally-regulated endothelial cell locus 1 protein
UniProt Protein Name:	EGF-like repeat and discoidin I-like domain-containing protein 3
UniProt Synonym Protein Names:	Developmentally-regulated endothelial cell locus 1 protein; Integrin-binding protein DEL1
Protein Family:	EGF-like repeat and discoidin I-like domain-containing protein
UniProt Gene Name:	EDIL3
UniProt Entry Name:	EDIL3_HUMAN

	Western blot analysis of extracts of various cell lines, using EDIL3 antibody (CAB15772) at 1:1000 dilution. Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) (CABS014) at 1:10000 dilution. Lysates/proteins: 25ug per lane. Blocking buffer: 3% nonfat dry milk in TBST. Detection: ECL Enhanced Kit (RM00021). Exposure time: 30s.
	Immunofluorescence analysis of U2OS cells using EDIL3 antibody (CAB15772) at dilution of 1:100. Blue: DAPI for nuclear staining.