Epigenetics & Nuclear Signaling Antibodies 2
Anti-EBF4 Antibody (CAB16139)
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- SKU:
- CAB16139
- Product Type:
- Antibody
- Reactivity:
- Human
- Reactivity:
- Mouse
- Host Species:
- Rabbit
- Isotype:
- IgG
- Antibody Type:
- Polyclonal Antibody
- Research Area:
- Epigenetics and Nuclear Signaling
Description
| Antibody Name: | Anti-EBF4 Antibody |
| Antibody SKU: | CAB16139 |
| Antibody Size: | 20uL, 50uL, 100uL |
| Application: | WB |
| Reactivity: | Human, Mouse |
| Host Species: | Rabbit |
| Immunogen: | A synthetic peptide corresponding to a sequence within amino acids 50-150 of human EBF4 (NP_001103984.1). |
| Application: | WB |
| Recommended Dilution: | WB 1:500 - 1:2000 |
| Reactivity: | Human, Mouse |
| Positive Samples: |
| Immunogen: | A synthetic peptide corresponding to a sequence within amino acids 50-150 of human EBF4 (NP_001103984.1). |
| Purification Method: | Affinity purification |
| Storage Buffer: | Store at -20'C. Avoid freeze / thaw cycles. Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3. |
| Isotype: | IgG |
| Sequence: | HFEK QPPS NLRK SNFF HFVL AMYD RQGQ PVEV ERTA FIDF VEKD REPG AEKT NNGI HYRL RLVY NNGL RTEQ DLYV RLID SMSK QAII YEGQ DKNP EMCR V |
| Gene ID: | 57593 |
| Uniprot: | Q9BQW3 |
| Cellular Location: | Nucleus |
| Calculated MW: | 64kDa/68kDa |
| Observed MW: | Refer to figures |
| Synonyms: | EBF4, COE4, O/E-4 |
| Background: | EBF4 belongs to the conserved Olf/EBF family of helix-loop-helix transcription factors, members of which play important roles in neural development and B-cell maturation. |
| UniProt Protein Function: | EBF4: Transcriptional factor which recognizes variations of the palindromic sequence 5'-ATTCCCNNGGGAATT-3'. Belongs to the COE family. 2 isoforms of the human protein are produced by alternative splicing. |
| UniProt Protein Details: | Chromosomal Location of Human Ortholog: 20p13 Cellular Component: nucleus Molecular Function:protein dimerization activity; DNA binding; metal ion binding Biological Process: transcription, DNA-dependent; regulation of transcription, DNA-dependent; multicellular organismal development |
| NCBI Summary: | EBF4 belongs to the conserved Olf/EBF family of helix-loop-helix transcription factors, members of which play important roles in neural development and B-cell maturation (Wang et al., 2002 [PubMed 12139918]).[supplied by OMIM, Mar 2008] |
| UniProt Code: | Q9BQW3 |
| NCBI GenInfo Identifier: | 160333411 |
| NCBI Gene ID: | 57593 |
| NCBI Accession: | NP_001103984.1 |
| UniProt Secondary Accession: | Q9BQW3,Q1MTP7, Q5JY53, Q9NUB6, Q9P2A6, |
| UniProt Related Accession: | Q9BQW3 |
| Molecular Weight: | 68,232 Da |
| NCBI Full Name: | transcription factor COE4 |
| NCBI Synonym Full Names: | early B-cell factor 4 |
| NCBI Official Symbol: | EBF4 |
| NCBI Official Synonym Symbols: | COE4; O/E-4 |
| NCBI Protein Information: | transcription factor COE4 |
| UniProt Protein Name: | Transcription factor COE4 |
| UniProt Synonym Protein Names: | Early B-cell factor 4; EBF-4; Olf-1/EBF-like 4; O/E-4; OE-4 |
| Protein Family: | Transcription factor |
| UniProt Gene Name: | EBF4 |
| UniProt Entry Name: | COE4_HUMAN |
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