Signal Transduction Antibodies 2

Anti-DYRK4 Antibody (CAB16460)

(No reviews yet) Write a Review
SKU:
CAB16460
Product Type:
Antibody
Reactivity:
Human
Reactivity:
Mouse
Reactivity:
Rat
Host Species:
Rabbit
Isotype:
IgG
Antibody Type:
Polyclonal Antibody
Research Area:
Signal Transduction

Description

system_update_altDatasheetsystem_update_altMSDS
Antibody Name:Anti-DYRK4 Antibody
Antibody SKU:CAB16460
Antibody Size:20uL, 50uL, 100uL
Application:WB
Reactivity:Human, Mouse, Rat
Host Species:Rabbit
Immunogen:Recombinant fusion protein containing a sequence corresponding to amino acids 330-480 of human DYRK4 (NP_003836.1).
Application:WB
Recommended Dilution:WB 1:500 - 1:2000
Reactivity:Human, Mouse, Rat
Positive Samples:293T, A-549, Jurkat, HepG2, C2C12, Rat testis
Immunogen:Recombinant fusion protein containing a sequence corresponding to amino acids 330-480 of human DYRK4 (NP_003836.1).
Purification Method:Affinity purification
Storage Buffer:Store at -20'C. Avoid freeze / thaw cycles. Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3.
Isotype:IgG
Sequence:TASR RQTF FDSK GFPK NITN NRGK KRYP DSKD LTMV LKTY DTSF LDFL RRCL VWEP SLRM TPDQ ALKH AWIH QSRN LKPQ PRPQ TLRK SNSF FPSE TRKD KVQG CHHS SRKA DEIT KETT EKTK DSPT KHVQ HSGD QQDC LQHG ADTV QLP
Gene ID:8798
Uniprot:Q9NR20
Cellular Location:Cytoplasm, Nucleus
Calculated MW:59kDa/72kDa/73kDa
Observed MW:73kDa
Synonyms:DYRK4
Background:This gene encodes an enzyme that belongs to a conserved family of serine/threonine protein kinases. Members of this dual specificity kinase family are thought to function in the regulation of cell differentiation and proliferation, survival, and in development. Alternate splicing results in multiple transcript variants. Additional alternatively spliced transcript variants of this gene have been described, but their full-length nature is not known.
UniProt Protein Function:DYRK4: a dual-specificity protein kinase of the DYRK family. Its expression is up-regulated by retinoic-acid-induced differentiation of a human neuronal precursor teratocarcinoma cell line.
UniProt Protein Details:

Protein type:Protein kinase, dual-specificity (non-receptor); Protein kinase, CMGC; EC 2.7.12.1; Kinase, protein; CMGC group; DYRK family; Dyrk2 subfamily

Chromosomal Location of Human Ortholog: 12p13.32

Cellular Component: intracellular membrane-bound organelle

Molecular Function:protein binding

NCBI Summary:This gene encodes an enzyme that belongs to a conserved family of serine/threonine protein kinases. Members of this dual specificity kinase family are thought to function in the regulation of cell differentiation and proliferation, survival, and in development. Alternate splicing results in multiple transcript variants. Additional alternatively spliced transcript variants of this gene have been described, but their full-length nature is not known. [provided by RefSeq, Aug 2013]
UniProt Code:Q9NR20
NCBI GenInfo Identifier:68566308
NCBI Gene ID:8798
NCBI Accession:Q9NR20.2
UniProt Secondary Accession:Q9NR20,Q8NEF2, Q92631, A8K8F7,
UniProt Related Accession:Q9NR20
Molecular Weight:59,293 Da
NCBI Full Name:Dual specificity tyrosine-phosphorylation-regulated kinase 4
NCBI Synonym Full Names:dual specificity tyrosine phosphorylation regulated kinase 4
NCBI Official Symbol:DYRK4  
NCBI Protein Information:dual specificity tyrosine-phosphorylation-regulated kinase 4
UniProt Protein Name:Dual specificity tyrosine-phosphorylation-regulated kinase 4
Protein Family:Dual specificity tyrosine-phosphorylation-regulated kinase
UniProt Gene Name:DYRK4  
UniProt Entry Name:DYRK4_HUMAN
Anti-DYRK4 Antibody (CAB16460)Western blot analysis of extracts of various cell lines, using DYRK4 antibody (CAB16460) at 1:1000 dilution. Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) (CABS014) at 1:10000 dilution. Lysates/proteins: 25ug per lane. Blocking buffer: 3% nonfat dry milk in TBST. Detection: ECL Basic Kit (RM00020). Exposure time: 60s.
View AllClose

0 Reviews

View AllClose

Related Products