Cell Cycle Antibodies 1

Anti-DYNLT3 Antibody (CAB16982)

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SKU:
CAB16982
Product Type:
Antibody
Reactivity:
Human
Reactivity:
Mouse
Host Species:
Rabbit
Isotype:
IgG
Antibody Type:
Polyclonal Antibody
Research Area:
Cell Cycle

Description

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Antibody Name:Anti-DYNLT3 Antibody
Antibody SKU:CAB16982
Antibody Size:20uL, 50uL, 100uL
Application:WB
Reactivity:Human, Mouse
Host Species:Rabbit
Immunogen:Recombinant fusion protein containing a sequence corresponding to amino acids 9-99 of human DYNLT3 (NP_006511.1).
Application:WB
Recommended Dilution:WB 1:500 - 1:2000
Reactivity:Human, Mouse
Positive Samples:
Immunogen:Recombinant fusion protein containing a sequence corresponding to amino acids 9-99 of human DYNLT3 (NP_006511.1).
Purification Method:Affinity purification
Storage Buffer:Store at -20'C. Avoid freeze / thaw cycles. Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3.
Isotype:IgG
Sequence:DEVG FNAE EAHN IVKE CVDG VLGG EDYN HNNI NQWT ASIV EQSL THLV KLGK AYKY IVTC AVVQ KSAY GFHT ASSC FWDT TSDG TCTV RWE
Gene ID:6990
Uniprot:P51808
Cellular Location:
Calculated MW:13kDa
Observed MW:Refer to figures
Synonyms:DYNLT3, RP3, TCTE1L, TCTEX1L
Background:This gene encodes a member of a subclass of dynein light chains. The encoded protein homodimerizes and forms the light chain component of the cytoplasmic dynein motor protein complex. This protein may be important for binding dynein to specific cargos including the spindle checkpoint protein BUB3. This protein may also function independently of dynein as a transcriptional modulator. Pseudogenes of this gene are found on chromosomes 2 and 20.
UniProt Protein Function:Acts as one of several non-catalytic accessory components of the cytoplasmic dynein 1 complex that are thought to be involved in linking dynein to cargos and to adapter proteins that regulate dynein function. Cytoplasmic dynein 1 acts as a motor for the intracellular retrograde motility of vesicles and organelles along microtubules. Probably binds BUB3 as part of transport cargo. Required for the efficient progression through mitosis.
NCBI Summary:This gene encodes a member of a subclass of dynein light chains. The encoded protein homodimerizes and forms the light chain component of the cytoplasmic dynein motor protein complex. This protein may be important for binding dynein to specific cargos including the spindle checkpoint protein BUB3. This protein may also function independently of dynein as a transcriptional modulator. Pseudogenes of this gene are found on chromosomes 2 and 20.[provided by RefSeq, Mar 2010]
UniProt Code:P51808
NCBI GenInfo Identifier:5730087
NCBI Gene ID:6990
NCBI Accession:NP_006511.1
UniProt Secondary Accession:P51808,Q6ICS3,
UniProt Related Accession:P51808
Molecular Weight:12
NCBI Full Name:dynein light chain Tctex-type 3
NCBI Synonym Full Names:dynein light chain Tctex-type 3
NCBI Official Symbol:DYNLT3  
NCBI Official Synonym Symbols:RP3; TCTE1L; TCTEX1L  
NCBI Protein Information:dynein light chain Tctex-type 3
UniProt Protein Name:Dynein light chain Tctex-type 3
UniProt Synonym Protein Names:Protein 91/23; T-complex-associated testis-expressed 1-like
UniProt Gene Name:DYNLT3  
Anti-DYNLT3 Antibody (CAB16982)Western blot analysis of extracts of various cell lines, using DYNLT3 antibody (CAB16982) at 1:1000 dilution. Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) (CABS014) at 1:10000 dilution. Lysates/proteins: 25ug per lane. Blocking buffer: 3% nonfat dry milk in TBST. Detection: ECL Basic Kit (RM00020). Exposure time: 1s.
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