Cell Biology Antibodies 9

Anti-DYNC2LI1 Antibody (CAB4752)

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SKU:
CAB4752
Product Type:
Antibody
Antibody Type:
Polyclonal Antibody
Reactivity:
Human
Reactivity:
Mouse
Reactivity:
Rat
Host Species:
Rabbit
Isotype:
IgG
Synonyms:
DYNC2LI1
Synonyms:
CGI-60
Synonyms:
D2LIC
Synonyms:
LIC3
Research Area:
Cell Biology

Description

Product Name:DYNC2LI1 Rabbit pAb
Product Code:CAB4752
Size:20uL, 50uL, 100uL
Synonyms:DYNC2LI1, CGI-60, D2LIC, LIC3
Applications:WB
Reactivity:Human, Mouse, Rat
Host Species:Rabbit
Immunogen:Recombinant fusion protein containing a sequence corresponding to amino acids 1-352 of human DYNC2LI1 (NP_001180393.1).
Applications:WB
Recommended Dilutions:WB 1:500 - 1:2000
Reactivity:Human, Mouse, Rat
Positive Samples:U-251MG, Jurkat, 293T, A-549, Mouse testis, Mouse eye, Mouse kidney, Rat testis
Immunogen:Recombinant fusion protein containing a sequence corresponding to amino acids 1-352 of human DYNC2LI1 (NP_001180393.1).
Purification Method:Affinity purification
Storage:Store at -20°C. Avoid freeze / thaw cycles. Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3.
Isotype:IgG
Sequence:MPSE TLWE IAKA EVEK RGIN GSEG DGAE IAEK FVFF IGSK NGGK TTII LRCL DRDE PPKP TLAL EYTY GRRA KGHN TPKD IAHF WELG GGTS LLDL ISIP ITGD TLRT FSLV LVLD LSKP NDLW PTME NLLQ ATKS HVDK VIMK LGKT NAKA VSEM RQKI WNNM PKDH PQDH ELID PFPV PLVI IGSK YDVF QDFE SEKR KVIC KTLR FVAH YYGA SLMF TSKS EALL LKIR GVIN QLAF GIDK SKSI CVDQ NKPL FITA GLDS FGQI GSPP VPEN DIGK LHAH SPME LWKK VYEK LFPP KSIN TLKD IKDP ARDP QYAE NEVD EMRI QKDL ELEQ YKRS SSKS WKQI ELDS
Gene ID:51626
Uniprot:Q8TCX1
Cellular Location:Cytoplasm, cilium axoneme, cytoskeleton
Calculated MW:15kDa/22kDa/37kDa/39kDa
Observed MW:38kDa
UniProt Protein Function:DYNC2LI1: May function as a motor for intraflagellar retrograde transport. Functions in cilia biogenesis. Belongs to the dynein light intermediate chain family. 5 isoforms of the human protein are produced by alternative splicing.
UniProt Protein Details:

Chromosomal Location of Human Ortholog: 2p25.1-p24.1

Cellular Component: axonemal dynein complex; apical part of cell; cytoplasmic microtubule; motile primary cilium; axoneme; cytosol

Molecular Function:protein binding; motor activity

Biological Process: metabolic process; organelle organization and biogenesis; antigen processing and presentation of exogenous peptide antigen via MHC class II; cilium biogenesis; determination of left/right symmetry

UniProt Code:Q8TCX1
NCBI GenInfo Identifier:74715850
NCBI Gene ID:51626
NCBI Accession:Q8TCX1.1
UniProt Secondary Accession:Q8TCX1,Q53F57, Q6PDB2, Q8IWA3, Q96B03, Q96J00, Q9Y370 Q9Y3S9, A8MVJ5,
UniProt Related Accession:Q8TCX1
Molecular Weight:351
NCBI Full Name:Cytoplasmic dynein 2 light intermediate chain 1
NCBI Synonym Full Names:dynein, cytoplasmic 2, light intermediate chain 1
NCBI Official Symbol:DYNC2LI1  
NCBI Official Synonym Symbols:LIC3; D2LIC; CGI-60  
NCBI Protein Information:cytoplasmic dynein 2 light intermediate chain 1
UniProt Protein Name:Cytoplasmic dynein 2 light intermediate chain 1
Protein Family:Cytoplasmic dynein
UniProt Gene Name:DYNC2LI1  
UniProt Entry Name:DC2L1_HUMAN
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