Anti-DYNC1LI2 Antibody (CAB20592)
- SKU:
- CAB20592
- Product Type:
- Antibody
- Antibody Type:
- Polyclonal Antibody
- Reactivity:
- Human
- Reactivity:
- Mouse
- Reactivity:
- Rat
- Host Species:
- Rabbit
- Isotype:
- IgG
- Synonyms:
- LIC2
- Synonyms:
- DNCLI2
Description
| Product Name: | DYNC1LI2 Rabbit pAb |
| Product Code: | CAB20592 |
| Size: | 50uL, 100uL |
| Synonyms: | LIC2, DNCLI2 |
| Applications: | WB |
| Reactivity: | Human, Mouse, Rat |
| Host Species: | Rabbit |
| Immunogen: | Recombinant protein of human DYNC1LI2 |
| Applications: | WB |
| Recommended Dilutions: | WB 1:500 - 1:2000 |
| Reactivity: | Human, Mouse, Rat |
| Positive Samples: | Mouse testis, Mouse brain, Rat lung, Rat brain |
| Immunogen: | Recombinant protein of human DYNC1LI2 |
| Purification Method: | Affinity purification |
| Storage: | Store at -20°C. Avoid freeze / thaw cycles. Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3. |
| Isotype: | IgG |
| Sequence: | Email for sequence |
| Gene ID: | 1783 |
| Uniprot: | O43237 |
| Calculated MW: | 54kDa |
| Observed MW: | 54KDa |
| UniProt Protein Function: | DNCLI2: Acts as one of several non-catalytic accessory components of the cytoplasmic dynein 1 complex that are thought to be involved in linking dynein to cargos and to adapter proteins that regulate dynein function. Cytoplasmic dynein 1 acts as a motor for the intracellular retrograde motility of vesicles and organelles along microtubules. May play a role in binding dynein to membranous organelles or chromosomes. Belongs to the dynein light intermediate chain family. Protein type: Motility/polarity/chemotaxis Chromosomal Location of Human Ortholog: 16q22.1 Cellular Component: centrosome; microtubule; membrane; cytoplasmic dynein complex; cytosol Molecular Function: microtubule motor activity; ATP binding Biological Process: centrosome localization; transport; metabolic process; antigen processing and presentation of exogenous peptide antigen via MHC class II; microtubule cytoskeleton organization and biogenesis; microtubule-based movement |
| UniProt Protein Details: | |
| NCBI Summary: | Cytoplasmic dynein is a microtubule-associated motor protein (Hughes et al., 1995 [PubMed 7738094]). See DYNC1H1 (MIM 600112) for general information about dyneins.[supplied by OMIM, Mar 2008] |
| UniProt Code: | O43237 |
| NCBI GenInfo Identifier: | 5453634 |
| NCBI Gene ID: | 1783 |
| NCBI Accession: | NP_006132.1 |
| UniProt Secondary Accession: | O43237,Q8TAT3, A8K6V1, B4DZP4 |
| UniProt Related Accession: | O43237 |
| Molecular Weight: | 45,005 Da |
| NCBI Full Name: | cytoplasmic dynein 1 light intermediate chain 2 isoform 1 |
| NCBI Synonym Full Names: | dynein, cytoplasmic 1, light intermediate chain 2 |
| NCBI Official Symbol: | DYNC1LI2 |
| NCBI Official Synonym Symbols: | LIC2; DNCLI2 |
| NCBI Protein Information: | cytoplasmic dynein 1 light intermediate chain 2; LIC-2; LIC53/55; dynein light intermediate chain 2, cytosolic; dynein, cytoplasmic, light intermediate polypeptide 2 |
| UniProt Protein Name: | Cytoplasmic dynein 1 light intermediate chain 2 |
| UniProt Synonym Protein Names: | Dynein light intermediate chain 2, cytosolic; LIC-2; LIC53/55 |
| Protein Family: | Cytoplasmic dynein |
| UniProt Gene Name: | DYNC1LI2 |
| UniProt Entry Name: | DC1L2_HUMAN |
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