Cell Biology Antibodies 6

Anti-DRP2 Antibody (CAB15663)

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SKU:
CAB15663
Product Type:
Antibody
Reactivity:
Mouse
Reactivity:
Rat
Host Species:
Rabbit
Isotype:
IgG
Antibody Type:
Polyclonal Antibody
Research Area:
Cell Biology

Description

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Antibody Name:Anti-DRP2 Antibody
Antibody SKU:CAB15663
Antibody Size:20uL, 50uL, 100uL
Application:WB
Reactivity:Mouse, Rat
Host Species:Rabbit
Immunogen:Recombinant fusion protein containing a sequence corresponding to amino acids 1-240 of human DRP2 (NP_001930.2).
Application:WB
Recommended Dilution:WB 1:500 - 1:2000
Reactivity:Mouse, Rat
Positive Samples:Mouse brain
Immunogen:Recombinant fusion protein containing a sequence corresponding to amino acids 1-240 of human DRP2 (NP_001930.2).
Purification Method:Affinity purification
Storage Buffer:Store at -20'C. Avoid freeze / thaw cycles. Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3.
Isotype:IgG
Sequence:MQPM VMQG CPYT LPRC HDWQ AADQ FHHS SSLR STCP HPQV RAAV TSPA PPQD GAGV PCLS LKLL NGSV GASG PLEP PAMN LCWN EIKK KSHN LRAR LEAF SDHS GKLQ LPLQ EIID WLSQ KDEE LSAQ LPLQ GDVA LVQQ EKET HAAF MEEV KSRG PYIY SVLE SAQA FLSQ HPFE ELEE PHSE SKDT SPKQ RIQN LSRF VWKQ ATVA SELW EKLT ARCV DQHR HIER TLEQ LLEI QGAM
Gene ID:1821
Uniprot:Q13474
Cellular Location:Cell junction, Cell membrane, Cell projection, Perikaryon, Peripheral membrane protein, dendrite, postsynaptic cell membrane, postsynaptic density, synapse
Calculated MW:99kDa/107kDa
Observed MW:88kDa
Synonyms:DRP2, DRP-2
Background:Members of the dystrophin family of proteins perform a critical role in the maintenance of membrane-associated complexes at points of intercellular contact in vertebrate cells. The protein encoded by this gene is predicted to resemble certain short C-terminal isoforms of dystrophin and dystrophin-related protein 1 (DRP1 or utrophin). DRP2 is expressed principally in the brain and spinal cord. Two transcript variants encoding different isoforms have been found for this gene.
UniProt Protein Function:Required for normal myelination and for normal organization of the cytoplasm and the formation of Cajal bands in myelinating Schwann cells. Required for normal PRX location at appositions between the abaxonal surface of the myelin sheath and the Schwann cell plasma membrane. Possibly involved in membrane-cytoskeleton interactions of the central nervous system.
NCBI Summary:Members of the dystrophin family of proteins perform a critical role in the maintenance of membrane-associated complexes at points of intercellular contact in vertebrate cells. The protein encoded by this gene is predicted to resemble certain short C-terminal isoforms of dystrophin and dystrophin-related protein 1 (DRP1 or utrophin). DRP2 is expressed principally in the brain and spinal cord. Two transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Jan 2010]
UniProt Code:Q13474
NCBI GenInfo Identifier:283945496
NCBI Gene ID:1821
NCBI Accession:NP_001164655.1
UniProt Secondary Accession:Q13474,A6ZKI5, A8K1B0, B1B1F3, B4DIZ0,
UniProt Related Accession:Q13474
Molecular Weight:99,793 Da
NCBI Full Name:dystrophin-related protein 2 isoform 2
NCBI Synonym Full Names:dystrophin related protein 2
NCBI Official Symbol:DRP2  
NCBI Official Synonym Symbols:DRP-2  
NCBI Protein Information:dystrophin-related protein 2
UniProt Protein Name:Dystrophin-related protein 2
Protein Family:Dystrophin-related protein
UniProt Gene Name:DRP2  
Anti-DRP2 Antibody (CAB15663)Western blot analysis of extracts of mouse brain, using DRP2 antibody (CAB15663) at 1:1000 dilution. Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) (CABS014) at 1:10000 dilution. Lysates/proteins: 25ug per lane. Blocking buffer: 3% nonfat dry milk in TBST. Detection: ECL Basic Kit (RM00020). Exposure time: 30s.
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