Cell Biology Antibodies 2

Anti-DPYSL5 Antibody (CAB10734)

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SKU:
CAB10734
Product Type:
Antibody
Reactivity:
Mouse
Host Species:
Rabbit
Isotype:
IgG
Antibody Type:
Polyclonal Antibody
Research Area:
Cell Biology

Description

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Antibody Name:Anti-DPYSL5 Antibody
Antibody SKU:CAB10734
Antibody Size:20uL, 50uL, 100uL
Application:WB
Reactivity:Mouse
Host Species:Rabbit
Immunogen:Recombinant fusion protein containing a sequence corresponding to amino acids 445-564 of human DPYSL5 (NP_064519.2).
Application:WB
Recommended Dilution:WB 1:500 - 1:2000
Reactivity:Mouse
Positive Samples:Mouse brain, Mouse liver, Mouse testis
Immunogen:Recombinant fusion protein containing a sequence corresponding to amino acids 445-564 of human DPYSL5 (NP_064519.2).
Purification Method:Affinity purification
Storage Buffer:Store at -20'C. Avoid freeze / thaw cycles. Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3.
Isotype:IgG
Sequence:VVYE NGVF MCAE GTGK FCPL RSFP DTVY KKLV QREK TLKV RGVD RTPY LGDV AVVV HPGK KEMG TPLA DTPT RPVT RHGG MRDL HESS FSLS GSQI DDHV PKRA SARI LAPP GGRS SGIW
Gene ID:56896
Uniprot:Q9BPU6
Cellular Location:Cytoplasm
Calculated MW:61kDa
Observed MW:61kDa
Synonyms:DPYSL5, CRAM, CRMP-5, CRMP5, Ulip6
Background:This gene encodes a member of the CRMP (collapsing response mediator protein) family thought to be involved in neural development. Antibodies to the encoded protein were found in some patients with neurologic symptoms who had paraneoplastic syndrome. A pseudogene of this gene is found on chromosome 11. Multiple alternatively spliced variants, encoding the same protein, have been identified.
UniProt Protein Function:CRMP-5: May have a function in neuronal differentiation and/or axon growth. Belongs to the DHOase family. Hydantoinase/dihydropyrimidinase subfamily.
UniProt Protein Details:

Chromosomal Location of Human Ortholog: 2p23.3

Cellular Component: cytosol

Molecular Function:protein binding

Biological Process: nervous system development; signal transduction

NCBI Summary:This gene encodes a member of the CRMP (collapsing response mediator protein) family thought to be involved in neural development. Antibodies to the encoded protein were found in some patients with neurologic symptoms who had paraneoplastic syndrome. A pseudogene of this gene is found on chromosome 11. Multiple alternatively spliced variants, encoding the same protein, have been identified. [provided by RefSeq, Dec 2011]
UniProt Code:Q9BPU6
NCBI GenInfo Identifier:20137929
NCBI Gene ID:56896
NCBI Accession:Q9BPU6.1
UniProt Secondary Accession:Q9BPU6,Q8TCL6, Q9NQC4, Q9NRY9,
UniProt Related Accession:Q9BPU6
Molecular Weight:61,421 Da
NCBI Full Name:Dihydropyrimidinase-related protein 5
NCBI Synonym Full Names:dihydropyrimidinase like 5
NCBI Official Symbol:DPYSL5  
NCBI Official Synonym Symbols:CRAM; CRMP5; Ulip6; CRMP-5  
NCBI Protein Information:dihydropyrimidinase-related protein 5
UniProt Protein Name:Dihydropyrimidinase-related protein 5
UniProt Synonym Protein Names:CRMP3-associated molecule; CRAM; Collapsin response mediator protein 5; CRMP-5; UNC33-like phosphoprotein 6; ULIP-6
Protein Family:Dihydropyrimidinase-related protein
UniProt Gene Name:DPYSL5  
UniProt Entry Name:DPYL5_HUMAN
Anti-DPYSL5 Antibody (CAB10734)Western blot analysis of extracts of various cell lines, using DPYSL5 antibody (CAB10734) at 1:3000 dilution. Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) (CABS014) at 1:10000 dilution. Lysates/proteins: 25ug per lane. Blocking buffer: 3% nonfat dry milk in TBST. Detection: ECL Basic Kit (RM00020). Exposure time: 1s.
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