Cell Biology Antibodies 15
Anti-DPY30 Antibody (CAB17796)
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- SKU:
- CAB17796
- Product Type:
- Antibody
- Reactivity:
- Human
- Host Species:
- Rabbit
- Isotype:
- IgG
- Antibody Type:
- Polyclonal Antibody
- Research Area:
- Cell Biology
Description
| Antibody Name: | Anti-DPY30 Antibody |
| Antibody SKU: | CAB17796 |
| Antibody Size: | 20uL, 50uL, 100uL |
| Application: | IHC |
| Reactivity: | Human |
| Host Species: | Rabbit |
| Immunogen: | Recombinant fusion protein containing a sequence corresponding to amino acids 1-99 of human DPY30 (NP_115963.1). |
| Application: | IHC |
| Recommended Dilution: | IHC 1:50 - 1:100 |
| Reactivity: | Human |
| Positive Samples: |
| Immunogen: | Recombinant fusion protein containing a sequence corresponding to amino acids 1-99 of human DPY30 (NP_115963.1). |
| Purification Method: | Affinity purification |
| Storage Buffer: | Store at -20°C. Avoid freeze / thaw cycles. Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3. |
| Isotype: | IgG |
| Sequence: | MEPE QMLE GQTQ VAEN PHSE YGLT DNVE RIVE NEKI NAEK SSKQ KVDL QSLP TRAY LDQT VVPI LLQG LAVL AKER PPNP IEFL ASYL LKNK AQFE DRN |
| Gene ID: | 84661 |
| Uniprot: | Q9C005 |
| Cellular Location: | |
| Calculated MW: | |
| Observed MW: | Refer to figures |
 | Immunohistochemistry - DPY30 Polyclonal Antibody (CAB17796) |
| Synonyms: | Cps25, HDPY-30, Saf19, DPY30 |
| Background: | This gene encodes an integral core subunit of the SET1/MLL family of H3K4 methyltransferases. The encoded protein directly controls cell cycle regulators and plays an important role in the proliferation and differentiation of human hematopoietic progenitor cells. [provided by RefSeq, Mar 2016] |
| UniProt Protein Function: | As part of the MLL1/MLL complex, involved in the methylation of histone H3 at 'Lys-4', particularly trimethylation. Histone H3 'Lys-4' methylation represents a specific tag for epigenetic transcriptional activation. May play some role in histone H3 acetylation. In a teratocarcinoma cell, plays a crucial role in retinoic acid-induced differentiation along the neural lineage, regulating gene induction and H3 'Lys-4' methylation at key developmental loci. May also play an indirect or direct role in endosomal transport. |
| NCBI Summary: | This gene encodes an integral core subunit of the SET1/MLL family of H3K4 methyltransferases. The encoded protein directly controls cell cycle regulators and plays an important role in the proliferation and differentiation of human hematopoietic progenitor cells. [provided by RefSeq, Mar 2016] |
| UniProt Code: | Q9C005 |
| NCBI GenInfo Identifier: | 14211889 |
| NCBI Gene ID: | 84661 |
| NCBI Accession: | NP_115963.1 |
| UniProt Secondary Accession: | Q9C005,D6W578, |
| UniProt Related Accession: | Q9C005 |
| Molecular Weight: | 11,250 Da |
| NCBI Full Name: | protein dpy-30 homolog isoform 1 |
| NCBI Synonym Full Names: | dpy-30, histone methyltransferase complex regulatory subunit |
| NCBI Official Symbol: | DPY30 |
| NCBI Official Synonym Symbols: | Cps25; Saf19; HDPY-30 |
| NCBI Protein Information: | protein dpy-30 homolog |
| UniProt Protein Name: | Protein dpy-30 homolog |
| UniProt Synonym Protein Names: | Dpy-30-like protein; Dpy-30L |
| Protein Family: | DPY30 domain-containing protein |
| UniProt Gene Name: | DPY30 |
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