Cell Biology Antibodies 10
Anti-DPP7 Antibody (CAB6579)
- SKU:
- CAB6579
- Product Type:
- Antibody
- Reactivity:
- Human
- Host Species:
- Rabbit
- Isotype:
- IgG
- Antibody Type:
- Polyclonal Antibody
- Research Area:
- Cell Biology
Description
Antibody Name: | Anti-DPP7 Antibody |
Antibody SKU: | CAB6579 |
Antibody Size: | 20uL, 50uL, 100uL |
Application: | WB IF |
Reactivity: | Human |
Host Species: | Rabbit |
Immunogen: | Recombinant fusion protein containing a sequence corresponding to amino acids 190-410 of human DPP7 (NP_037511.2). |
Application: | WB IF |
Recommended Dilution: | WB 1:500 - 1:2000 IF 1:50 - 1:100 |
Reactivity: | Human |
Positive Samples: |
Immunogen: | Recombinant fusion protein containing a sequence corresponding to amino acids 190-410 of human DPP7 (NP_037511.2). |
Purification Method: | Affinity purification |
Storage Buffer: | Store at -20'C. Avoid freeze / thaw cycles. Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3. |
Isotype: | IgG |
Sequence: | LAVA GLGD SNQF FRDV TADF EGQS PKCT QGVR EAFR QIKD LFLQ GAYD TVRW EFGT CQPL SDEK DLTQ LFMF ARNA FTVL AMMD YPYP TDFL GPLP ANPV KVGC DRLL SEAQ RITG LRAL AGLV YNAS GSEH CYDI YRLY HSCA DPTG CGTG PDAR AWDY QACT EINL TFAS NNVT DMFP DLPF TDEL RQRY CLDT WGVW PRPD WLLT SFWG GDLR AASN I |
Gene ID: | 29952 |
Uniprot: | Q9UHL4 |
Cellular Location: | Cytoplasmic vesicle, Lysosome, Secreted |
Calculated MW: | 54kDa |
Observed MW: | Refer to Figures |
Synonyms: | DPP7, DPP2, DPPII, QPP |
Background: | The protein encoded by this gene is a post-proline cleaving aminopeptidase expressed in quiescent lymphocytes. The resting lymphocytes are maintained through suppression of apoptosis, a state which is disrupted by inhibition of this novel serine protease. The enzyme has strong sequence homology with prolylcarboxypeptidase and is active at both acidic and neutral pH. |
UniProt Protein Function: | DPP7: Plays an important role in the degradation of some oligopeptides. Belongs to the peptidase S28 family. |
UniProt Protein Details: | Protein type:Secreted, signal peptide; EC 3.4.14.2; Protease; Secreted Chromosomal Location of Human Ortholog: 9q34.3 Cellular Component: Golgi apparatus; intracellular membrane-bound organelle; lysosome; cytoplasmic membrane-bound vesicle; cytosol Molecular Function:serine-type peptidase activity; dipeptidyl-peptidase activity Biological Process: proteolysis |
NCBI Summary: | The protein encoded by this gene is a post-proline cleaving aminopeptidase expressed in quiescent lymphocytes. The resting lymphocytes are maintained through suppression of apoptosis, a state which is disrupted by inhibition of this novel serine protease. The enzyme has strong sequence homology with prolylcarboxypeptidase and is active at both acidic and neutral pH. [provided by RefSeq, Jul 2008] |
UniProt Code: | Q9UHL4 |
NCBI GenInfo Identifier: | 212276510 |
NCBI Gene ID: | 29952 |
NCBI Accession: | Q9UHL4.3 |
UniProt Secondary Accession: | Q9UHL4,Q5VSF1, Q969X4, A8K7U7, |
UniProt Related Accession: | Q9UHL4 |
Molecular Weight: | 492 |
NCBI Full Name: | Dipeptidyl peptidase 2 |
NCBI Synonym Full Names: | dipeptidyl-peptidase 7 |
NCBI Official Symbol: | DPP7 |
NCBI Official Synonym Symbols: | QPP; DPP2; DPPII |
NCBI Protein Information: | dipeptidyl peptidase 2; DPP II; carboxytripeptidase; dipeptidyl peptidase II; dipeptidyl-peptidase II; dipeptidyl arylamidase II; dipeptidyl aminopeptidase II; quiescent cell proline dipeptidase |
UniProt Protein Name: | Dipeptidyl peptidase 2 |
UniProt Synonym Protein Names: | Dipeptidyl aminopeptidase II; Dipeptidyl peptidase 7; Dipeptidyl peptidase II; DPP II; Quiescent cell proline dipeptidase |
Protein Family: | Dipeptidyl peptidase |
UniProt Gene Name: | DPP7 |
UniProt Entry Name: | DPP2_HUMAN |
Immunofluorescence analysis of HeLa cells using DPP7 antibody (CAB6579). Blue: DAPI for nuclear staining. |
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