Cell Biology Antibodies 13
Anti-DPH2 Antibody (CAB17475)
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- SKU:
- CAB17475
- Product Type:
- Antibody
- Reactivity:
- Mouse
- Host Species:
- Rabbit
- Isotype:
- IgG
- Antibody Type:
- Polyclonal Antibody
- Research Area:
- Cell Biology
Description
| Antibody Name: | Anti-DPH2 Antibody |
| Antibody SKU: | CAB17475 |
| Antibody Size: | 20uL, 50uL, 100uL |
| Application: | WB |
| Reactivity: | Mouse |
| Host Species: | Rabbit |
| Immunogen: | Recombinant fusion protein containing a sequence corresponding to amino acids 120-330 of human DPH2 (NP_001375.2). |
| Application: | WB |
| Recommended Dilution: | WB 1:500 - 1:2000 |
| Reactivity: | Mouse |
| Positive Samples: | Mouse thymus |
| Immunogen: | Recombinant fusion protein containing a sequence corresponding to amino acids 120-330 of human DPH2 (NP_001375.2). |
| Purification Method: | Affinity purification |
| Storage Buffer: | Store at -20°C. Avoid freeze / thaw cycles. Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3. |
| Isotype: | IgG |
| Sequence: | VAFV LRQR SVAL ELCV KAFE AQNP DPKA PVVL LSEP ACAH ALEA LATL LRPR YLDL LVSS PAFP QPVG SLSP EPMP LERF GRRF PLAP GRRL EEYG AFYV GGSK ASPD PDLD PDLS RLLL GWAP GQPF SSCC PDTG KTQD EGAR AGRL RARR RYLV ERAR DARV VGLL AGTL GVAQ HREA LAHL RNLT QAAG KRSY VLAL GRPT PAKL ANF |
| Gene ID: | 1802 |
| Uniprot: | Q9BQC3 |
| Cellular Location: | |
| Calculated MW: | |
| Observed MW: | 50kDa |
 | Western blot - DPH2 Polyclonal Antibody (CAB17475) |
| Synonyms: | DPH2L2, DPH2 |
| Background: | This gene is one of two human genes similar to the yeast gene dph2. The yeast gene was identified by its ability to complement a diphthamide mutant strain, and thus probably functions in diphthamide biosynthesis. Diphthamide is a post-translationally modified histidine residue present in elongation factor 2 (EF2) that is the target of diphtheria toxin ADP-ribosylation. Multiple transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Jan 2016] |
| UniProt Protein Function: | Required for the first step in the synthesis of diphthamide, a post-translational modification of histidine which occurs in translation elongation factor 2 (EEF2). |
| NCBI Summary: | This gene is one of two human genes similar to the yeast gene dph2. The yeast gene was identified by its ability to complement a diphthamide mutant strain, and thus probably functions in diphthamide biosynthesis. Diphthamide is a post-translationally modified histidine residue present in elongation factor 2 (EF2) that is the target of diphtheria toxin ADP-ribosylation. Multiple transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Jan 2016] |
| UniProt Code: | Q9BQC3 |
| NCBI GenInfo Identifier: | 74761201 |
| NCBI Gene ID: | 1802 |
| NCBI Accession: | Q9BQC3.1 |
| UniProt Secondary Accession: | Q9BQC3,O60623, A8MVC9, B2RDE3, B4DNI8, |
| UniProt Related Accession: | Q9BQC3 |
| Molecular Weight: | 38,510 Da |
| NCBI Full Name: | 2-(3-amino-3-carboxypropyl)histidine synthase subunit 2 |
| NCBI Synonym Full Names: | DPH2 homolog |
| NCBI Official Symbol: | DPH2 |
| NCBI Official Synonym Symbols: | DPH2L2 |
| NCBI Protein Information: | 2-(3-amino-3-carboxypropyl)histidine synthase subunit 2; diphthamide biosynthesis protein 2 |
| UniProt Protein Name: | 2-(3-amino-3-carboxypropyl)histidine synthase subunit 2 |
| UniProt Synonym Protein Names: | Diphthamide biosynthesis protein 2; Diphtheria toxin resistance protein 2Curated; S-adenosyl-L-methionine:L-histidine 3-amino-3-carboxypropyltransferase 2Curated |
| Protein Family: | 2-(3-amino-3-carboxypropyl)histidine synthase |
| UniProt Gene Name: | DPH2 |
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