Cell Death Antibodies 2

Anti-DPF2 Antibody (CAB18258)

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SKU:
CAB18258
Product Type:
Antibody
Reactivity:
Human
Reactivity:
Mouse
Reactivity:
Rat
Host Species:
Rabbit
Isotype:
IgG
Research Area:
Cell Death

Description

system_update_altDatasheetsystem_update_altMSDS
Antibody Name:Anti-DPF2 Antibody
Antibody SKU:CAB18258
Antibody Size:20uL, 50uL, 100uL
Application:WB
Reactivity:Human, Mouse, Rat
Host Species:Rabbit
Immunogen:Recombinant protein of human DPF2.
Application:WB
Recommended Dilution:WB 1:500 - 1:2000
Reactivity:Human, Mouse, Rat
Positive Samples:HeLa, Mouse thymus, Mouse testis, Rat testis, Rat lung
Immunogen:Recombinant protein of human DPF2.
Purification Method:Affinity purification
Storage Buffer:Store at -20°C. Avoid freeze / thaw cycles. Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3.
Isotype:IgG
Sequence:Email for sequence
Gene ID:5977
Uniprot:Q92785
Cellular Location:
Calculated MW:23kDa/44kDa
Observed MW:40kDa
Anti-DPF2 Antibody (CAB18258)Western blot - DPF2 Polyclonal Antibody (CAB18258)
Synonyms:DPF2, REQ, UBID4, ubi-d4
Background:The protein encoded by this gene is a member of the d4 domain family, characterized by a zinc finger-like structural motif. This protein functions as a transcription factor which is necessary for the apoptotic response following deprivation of survival factors. It likely serves a regulatory role in rapid hematopoietic cell growth and turnover. This gene is considered a candidate gene for multiple endocrine neoplasia type I, an inherited cancer syndrome involving multiple parathyroid, enteropancreatic, and pituitary tumors.
UniProt Protein Function:requiem: May be a transcription factor required for the apoptosis response following survival factor withdrawal from myeloid cells. Might also have a role in the development and maturation of lymphoid cells. Belongs to the requiem/DPF family.
UniProt Protein Details:

Protein type:Apoptosis; C2H2-type zinc finger protein

Chromosomal Location of Human Ortholog: 11q13

Cellular Component: centrosome; cytoplasm; intracellular membrane-bound organelle; nuclear chromatin; nucleoplasm

Molecular Function:protein binding; zinc ion binding

Biological Process: apoptosis; regulation of transcription, DNA-dependent; transcription, DNA-dependent

NCBI Summary:The protein encoded by this gene is a member of the d4 domain family, characterized by a zinc finger-like structural motif. This protein functions as a transcription factor which is necessary for the apoptotic response following deprivation of survival factors. It likely serves a regulatory role in rapid hematopoietic cell growth and turnover. This gene is considered a candidate gene for multiple endocrine neoplasia type I, an inherited cancer syndrome involving multiple parathyroid, enteropancreatic, and pituitary tumors. [provided by RefSeq, Jul 2008]
UniProt Code:Q92785
NCBI GenInfo Identifier:2842711
NCBI Gene ID:5977
NCBI Accession:Q92785.2
UniProt Secondary Accession:Q92785,A8K7C9, B4DT58,
UniProt Related Accession:Q92785
Molecular Weight:23,599 Da
NCBI Full Name:Zinc finger protein ubi-d4
NCBI Synonym Full Names:double PHD fingers 2
NCBI Official Symbol:DPF2  
NCBI Official Synonym Symbols:REQ; UBID4; ubi-d4  
NCBI Protein Information:zinc finger protein ubi-d4
UniProt Protein Name:Zinc finger protein ubi-d4
UniProt Synonym Protein Names:Apoptosis response zinc finger protein; BRG1-associated factor 45D; BAF45D; D4, zinc and double PHD fingers family 2; Protein requiem
Protein Family:Zinc finger protein
UniProt Gene Name:DPF2  
UniProt Entry Name:REQU_HUMAN
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