Metabolism Antibodies 1
Anti-DPEP2 Antibody (CAB15502)
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- SKU:
- CAB15502
- Product Type:
- Antibody
- Reactivity:
- Human
- Reactivity:
- Mouse
- Reactivity:
- Rat
- Host Species:
- Rabbit
- Isotype:
- IgG
- Antibody Type:
- Polyclonal Antibody
- Research Area:
- Metabolism
Description
| Antibody Name: | Anti-DPEP2 Antibody |
| Antibody SKU: | CAB15502 |
| Antibody Size: | 20uL, 50uL, 100uL |
| Application: | WB |
| Reactivity: | Human, Mouse, Rat |
| Host Species: | Rabbit |
| Immunogen: | Recombinant fusion protein containing a sequence corresponding to amino acids 400-463 of human DPEP2 (NP_071750.1). |
| Application: | WB |
| Recommended Dilution: | WB 1:200 - 1:2000 |
| Reactivity: | Human, Mouse, Rat |
| Positive Samples: | HeLa, Mouse spleen, Rat spleen |
| Immunogen: | Recombinant fusion protein containing a sequence corresponding to amino acids 400-463 of human DPEP2 (NP_071750.1). |
| Purification Method: | Affinity purification |
| Storage Buffer: | Store at -20'C. Avoid freeze / thaw cycles. Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3. |
| Isotype: | IgG |
| Sequence: | VEKV QEEN KWQS PLED KFPD EQLS SSCH SDLS RLRQ RQSL TSGQ ELTE IPIH WTAK LPAK WSVS |
| Gene ID: | 64174 |
| Uniprot: | Q9H4A9 |
| Cellular Location: | GPI-anchor, Lipid-anchor, Membrane |
| Calculated MW: | 43kDa/53kDa |
| Observed MW: | 53kDa |
| Synonyms: | DPEP2, MBD2 |
| Background: |
| UniProt Protein Function: | DPEP2: Probable metalloprotease which hydrolyzes leukotriene D4 (LTD4) into leukotriene E4 (LTE4). Belongs to the peptidase M19 family. 2 isoforms of the human protein are produced by alternative splicing. |
| UniProt Protein Details: | Protein type:Secreted, signal peptide; Membrane protein, GPI anchor; Protease; Secreted; EC 3.4.13.19 Chromosomal Location of Human Ortholog: 16q22.1 |
| NCBI Summary: | DPEP2 belongs to the membrane-bound dipeptidase (EC 3.4.13.19) family. These enzymes hydrolyze a variety of dipeptides, including leukotriene D4, the beta-lactam ring of some antibiotics, and cystinyl-bis-glycine (cys-bis-gly) formed during glutathione degradation (Habib et al., 2003 [PubMed 12738806]).[supplied by OMIM, Mar 2008] |
| UniProt Code: | Q9H4A9 |
| NCBI GenInfo Identifier: | 296434482 |
| NCBI Gene ID: | 64174 |
| NCBI Accession: | Q9H4A9.2 |
| UniProt Secondary Accession: | Q9H4A9,Q6UX92, Q8TC95, B2RCF8, |
| UniProt Related Accession: | Q9H4A9 |
| Molecular Weight: | 43,828 Da |
| NCBI Full Name: | Dipeptidase 2 |
| NCBI Synonym Full Names: | dipeptidase 2 |
| NCBI Official Symbol: | DPEP2 |
| NCBI Official Synonym Symbols: | MBD2 |
| NCBI Protein Information: | dipeptidase 2 |
| UniProt Protein Name: | Dipeptidase 2 |
| Protein Family: | Dipeptidase |
| UniProt Gene Name: | DPEP2 |
| UniProt Entry Name: | DPEP2_HUMAN |
 | Western blot analysis of extracts of various cell lines, using DPEP2 antibody (CAB15502) at 1:1000 dilution. Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) (CABS014) at 1:10000 dilution. Lysates/proteins: 25ug per lane. Blocking buffer: 3% nonfat dry milk in TBST. Detection: ECL Basic Kit (RM00020). Exposure time: 90s. |
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