Cell Biology Antibodies 7
Anti-DOCK1 Antibody (CAB17359)
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- SKU:
- CAB17359
- Product Type:
- Antibody
- Reactivity:
- Human
- Host Species:
- Rabbit
- Isotype:
- IgG
- Antibody Type:
- Polyclonal Antibody
- Research Area:
- Cell Biology
Description
| Antibody Name: | Anti-DOCK1 Antibody |
| Antibody SKU: | CAB17359 |
| Antibody Size: | 20uL, 50uL, 100uL |
| Application: | WB |
| Reactivity: | Human |
| Host Species: | Rabbit |
| Immunogen: | Recombinant protein of human DOCK1. |
| Application: | WB |
| Recommended Dilution: | WB 1:500 - 1:2000 |
| Reactivity: | Human |
| Positive Samples: | 293T |
| Immunogen: | Recombinant protein of human DOCK1. |
| Purification Method: | Affinity purification |
| Storage Buffer: | Store at -20'C. Avoid freeze / thaw cycles. Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3. |
| Isotype: | IgG |
| Sequence: | Email for sequence |
| Gene ID: | 1793 |
| Uniprot: | B2RUU3 |
| Cellular Location: | |
| Calculated MW: | 215kDa |
| Observed MW: | 215kDa |
| Synonyms: | ced5, DOCK180, DOCK1 |
| Background: | This gene encodes a member of the dedicator of cytokinesis protein family. Dedicator of cytokinesis proteins act as guanine nucleotide exchange factors for small Rho family G proteins. The encoded protein regulates the small GTPase Rac, thereby influencing several biological processes, including phagocytosis and cell migration. Overexpression of this gene has also been associated with certain cancers. Alternative splicing results in multiple transcript variants. |
| NCBI Summary: | This gene encodes a member of the dedicator of cytokinesis protein family. Dedicator of cytokinesis proteins act as guanine nucleotide exchange factors for small Rho family G proteins. The encoded protein regulates the small GTPase Rac, thereby influencing several biological processes, including phagocytosis and cell migration. Overexpression of this gene has also been associated with certain cancers. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Mar 2014] |
| UniProt Code: | B2RUU3 |
| NCBI GenInfo Identifier: | |
| NCBI Gene ID: | 1793 |
| NCBI Accession: | |
| UniProt Related Accession: | Q14185 |
| Molecular Weight: | 215kDa |
| NCBI Full Name: | |
| NCBI Synonym Full Names: | dedicator of cytokinesis 1 |
| NCBI Official Symbol: | DOCK1 |
| NCBI Official Synonym Symbols: | ced5; DOCK180 |
| NCBI Protein Information: | dedicator of cytokinesis protein 1 |
| UniProt Protein Name: | |
| Protein Family: | Dedicator of cytokinesis protein |
| UniProt Gene Name: |
 | Western blot analysis of extracts of 293T cells, using DOCK1 antibody (CAB17359) at 1:1000 dilution. Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) (CABS014) at 1:10000 dilution. Lysates/proteins: 25ug per lane. Blocking buffer: 3% nonfat dry milk in TBST. Detection: ECL Basic Kit (RM00020). Exposure time: 3min. |
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