Epigenetics & Nuclear Signaling Antibodies 2
Anti-DNTTIP2 Antibody (CAB16120)
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- SKU:
- CAB16120
- Product Type:
- Antibody
- Reactivity:
- Human
- Reactivity:
- Mouse
- Host Species:
- Rabbit
- Isotype:
- IgG
- Antibody Type:
- Polyclonal Antibody
- Research Area:
- Epigenetics and Nuclear Signaling
Description
| Antibody Name: | Anti-DNTTIP2 Antibody |
| Antibody SKU: | CAB16120 |
| Antibody Size: | 20uL, 50uL, 100uL |
| Application: | WB IF |
| Reactivity: | Human, Mouse |
| Host Species: | Rabbit |
| Immunogen: | Recombinant fusion protein containing a sequence corresponding to amino acids 1-300 of human DNTTIP2 (NP_055412.2). |
| Application: | WB IF |
| Recommended Dilution: | WB 1:500 - 1:2000 IF 1:50 - 1:200 |
| Reactivity: | Human, Mouse |
| Positive Samples: | Mouse pancreas |
| Immunogen: | Recombinant fusion protein containing a sequence corresponding to amino acids 1-300 of human DNTTIP2 (NP_055412.2). |
| Purification Method: | Affinity purification |
| Storage Buffer: | Store at -20'C. Avoid freeze / thaw cycles. Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3. |
| Isotype: | IgG |
| Sequence: | MVVT RSAR AKAS IQAA SAES SGQK SFAA NGIQ AHPE SSTG SDAR TTAE SQTT GKQS LIPR TPKA RKRK SRTT GSLP KGTE PSTD GETS EAES NYSV SEHH DTIL RVTR RRQI LIAC SPVS SVRK KPKV TPTK ESYT EEIV SEAE SHVS GISR IVLP TEKT TGAR RSKA KSLT DPSQ ESHT EAIS DAET SSSD ISFS GIAT RRTR SMQR KLKA QTEK KDSK IVPG NEKQ IVGT PVNS EDSD TRQT SHLQ ARSL SEIN KPNF YNND FDDD FSHR SSEN ILTV HEQA NVES LKET KQNC KDLD |
| Gene ID: | 30836 |
| Uniprot: | Q5QJE6 |
| Cellular Location: | Nucleus |
| Calculated MW: | 84kDa |
| Observed MW: | 105kDa |
| Synonyms: | DNTTIP2, ERBP, FCF2, HSU15552, LPTS-RP2, TdIF2 |
| Background: | This gene is thought to be involved in chromatin remodeling and gene transcription. The encoded nuclear protein binds to and enhances the transcriptional activity of the estrogen receptor alpha, and also interacts with terminal deoxynucleotidyltransferase. The expression profile of this gene is a potential biomarker for chronic obstructive pulmonary disease. |
| UniProt Protein Function: | ERBP: Regulates the transcriptional activity of DNTT and ESR1. May function as a chromatin remodeling protein. |
| UniProt Protein Details: | Protein type:Nuclear receptor co-regulator; Transcription, coactivator/corepressor Chromosomal Location of Human Ortholog: 1p22.1 Cellular Component: nucleolus; nucleus Biological Process: transcription, DNA-dependent; regulation of transcription, DNA-dependent |
| NCBI Summary: | This gene is thought to be involved in chromatin remodeling and gene transcription. The encoded nuclear protein binds to and enhances the transcriptional activity of the estrogen receptor alpha, and also interacts with terminal deoxynucleotidyltransferase. The expression profile of this gene is a potential biomarker for chronic obstructive pulmonary disease. [provided by RefSeq, Dec 2010] |
| UniProt Code: | Q5QJE6 |
| NCBI GenInfo Identifier: | 54633315 |
| NCBI Gene ID: | 30836 |
| NCBI Accession: | NP_055412.2 |
| UniProt Secondary Accession: | Q5QJE6,Q12987, Q53H59, Q5TFJ4, Q6TLI0, Q76MJ8, Q86WX9 |
| UniProt Related Accession: | Q5QJE6 |
| Molecular Weight: | 84,469 Da |
| NCBI Full Name: | deoxynucleotidyltransferase terminal-interacting protein 2 |
| NCBI Synonym Full Names: | deoxynucleotidyltransferase, terminal, interacting protein 2 |
| NCBI Official Symbol: | DNTTIP2 |
| NCBI Official Synonym Symbols: | ERBP; FCF2; TdIF2; HSU15552; LPTS-RP2 |
| NCBI Protein Information: | deoxynucleotidyltransferase terminal-interacting protein 2 |
| UniProt Protein Name: | Deoxynucleotidyltransferase terminal-interacting protein 2 |
| UniProt Synonym Protein Names: | Estrogen receptor-binding protein; LPTS-interacting protein 2; LPTS-RP2; Terminal deoxynucleotidyltransferase-interacting factor 2; TdIF2; TdT-interacting factor 2 |
| Protein Family: | Deoxynucleotidyltransferase terminal-interacting protein |
| UniProt Gene Name: | DNTTIP2 |
| UniProt Entry Name: | TDIF2_HUMAN |
 | Western blot analysis of extracts of mouse pancreas, using DNTTIP2 antibody (CAB16120) at 1:1000 dilution. Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) (CABS014) at 1:10000 dilution. Lysates/proteins: 25ug per lane. Blocking buffer: 3% nonfat dry milk in TBST. Detection: ECL Basic Kit (RM00020). Exposure time: 10s. |
 | Immunofluorescence analysis of U-2 OS cells using DNTTIP2 antibody (CAB16120) at dilution of 1:100. Blue: DAPI for nuclear staining. |
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