Cell Biology Antibodies 10

Anti-DNM3 Antibody (CAB7092)

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SKU:
CAB7092
Product Type:
Antibody
Reactivity:
Human
Reactivity:
Mouse
Host Species:
Rabbit
Isotype:
IgG
Antibody Type:
Polyclonal Antibody
Research Area:
Cell Biology

Description

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Antibody Name:Anti-DNM3 Antibody
Antibody SKU:CAB7092
Antibody Size:20uL, 50uL, 100uL
Application:WB
Reactivity:Human, Mouse
Host Species:Rabbit
Immunogen:Recombinant fusion protein containing a sequence corresponding to amino acids 594-863 of human DNM3 (NP_056384.2).
Application:WB
Recommended Dilution:WB 1:500 - 1:2000
Reactivity:Human, Mouse
Positive Samples:Mouse brain
Immunogen:Recombinant fusion protein containing a sequence corresponding to amino acids 594-863 of human DNM3 (NP_056384.2).
Purification Method:Affinity purification
Storage Buffer:Store at -20'C. Avoid freeze / thaw cycles. Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3.
Isotype:IgG
Sequence:KDYR FLEL ACDS QEDV DSWK ASLL RAGV YPDK SVGN NKAE NDEN GQAE NFSM DPQL ERQV ETIR NLVD SYMS IINK CIRD LIPK TIMH LMIN NVKD FINS ELLA QLYS SEDQ NTLM EESA EQAQ RRDE MLRM YQAL KEAL GIIG DIST ATVS TPAP PPVD DSWI QHSR RSPP PSPT TQRR PTLS APLA RPTS GRGP APAI PSPG PHSG APPV PFRP GPLP PFPS SSDS FGAP PQVP SRPT RAPP SVPS RRPP PSPT RPTI IRPL ESSL LD
Gene ID:26052
Uniprot:Q9UQ16
Cellular Location:Cytoplasm, cytoskeleton
Calculated MW:62kDa/96kDa/97kDa/98kDa
Observed MW:98kDa
Synonyms:DNM3, Dyna III, DynaIII, dynamin-3
Background:This gene encodes a member of a family of guanosine triphosphate (GTP)-binding proteins that associate with microtubules and are involved in vesicular transport. The encoded protein functions in the development of megakaryocytes. Alternative splicing results in multiple transcript variants.
UniProt Protein Function:DYN3: a microtubule-associated force-producing protein involved in producing microtubule bundles and able to bind and hydrolyze GTP. Most probably involved in vesicular trafficking processes. Concentrates within dendritic spine tips of the postsynaptic compartment and interacts with mGluR5 and Homer. May play a role in dendritic spine morphogenesis and remodeling.
UniProt Protein Details:

Protein type:Mitochondrial; Vesicle; EC 3.6.5.5; Microtubule-binding; Motility/polarity/chemotaxis; Hydrolase; Motor

Chromosomal Location of Human Ortholog: 1q24.3

Cellular Component: dendritic spine; perinuclear region of cytoplasm; postsynaptic density

Molecular Function:GTPase activity; protein binding

Biological Process: endocytosis; filopodium formation; synaptogenesis

NCBI Summary:This gene encodes a member of a family of guanosine triphosphate (GTP)-binding proteins that associate with microtubules and are involved in vesicular transport. The encoded protein functions in the development of megakaryocytes. Alternative splicing results in multiple transcript variants. [provided by RefSeq, May 2013]
UniProt Code:Q9UQ16
NCBI GenInfo Identifier:190358934
NCBI Gene ID:26052
NCBI Accession:Q9UQ16.4
UniProt Secondary Accession:Q9UQ16,O14982, O95555, Q1MTM8, Q5W129, Q6P2G1, Q9H0P3 Q9H548, Q9NQ68, Q9NQN6, A9Z1Y1,
UniProt Related Accession:Q9UQ16
Molecular Weight:62,824 Da
NCBI Full Name:Dynamin-3
NCBI Synonym Full Names:dynamin 3
NCBI Official Symbol:DNM3  
NCBI Official Synonym Symbols:Dyna III  
NCBI Protein Information:dynamin-3
UniProt Protein Name:Dynamin-3
UniProt Synonym Protein Names:Dynamin, testicular; T-dynamin
Protein Family:Dynamin
UniProt Gene Name:DNM3  
UniProt Entry Name:DYN3_HUMAN
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