Signal Transduction Antibodies 2
Anti-DNER Antibody (CAB15551)
(No reviews yet)
Write a Review
- SKU:
- CAB15551
- Product Type:
- Antibody
- Reactivity:
- Human
- Reactivity:
- Mouse
- Reactivity:
- Rat
- Host Species:
- Rabbit
- Isotype:
- IgG
- Antibody Type:
- Polyclonal Antibody
- Research Area:
- Signal Transduction
Description
| Antibody Name: | Anti-DNER Antibody |
| Antibody SKU: | CAB15551 |
| Antibody Size: | 20uL, 50uL, 100uL |
| Application: | WB IF |
| Reactivity: | Human, Mouse, Rat |
| Host Species: | Rabbit |
| Immunogen: | Recombinant fusion protein containing a sequence corresponding to amino acids 140-240 of human DNER (NP_620711.3). |
| Application: | WB IF |
| Recommended Dilution: | WB 1:200 - 1:2000 IF 1:50 - 1:200 |
| Reactivity: | Human, Mouse, Rat |
| Positive Samples: | Hela, HT-29, Mouse brain, Mouse eye, Mouse small intestine, Rat brain |
| Immunogen: | Recombinant fusion protein containing a sequence corresponding to amino acids 140-240 of human DNER (NP_620711.3). |
| Purification Method: | Affinity purification |
| Storage Buffer: | Store at -20'C. Avoid freeze / thaw cycles. Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3. |
| Isotype: | IgG |
| Sequence: | PATG WTES MAPR QLQP VPAT QEPD KILP RSQA TVTL PTWQ PKTG QKVV EMKW DQVE VIPD IACG NASS NSSA GGRL VSFE VPQN TSVK IRQD ATAS LILL W |
| Gene ID: | 92737 |
| Uniprot: | Q8NFT8 |
| Cellular Location: | Cell membrane, Single-pass type I membrane protein |
| Calculated MW: | 78kDa |
| Observed MW: | 80kDa |
| Synonyms: | DNER, UNQ26, bet |
| Background: |
| UniProt Protein Function: | DNER: Activator of the NOTCH1 pathway. May mediate neuron-glia interaction during astrocytogenesis. |
| UniProt Protein Details: | Protein type:Membrane protein, integral; Receptor, misc. Chromosomal Location of Human Ortholog: 2q36.3 Cellular Component: dendrite; early endosome; plasma membrane Molecular Function:clathrin binding; protein binding; transmembrane receptor activity Biological Process: central nervous system development |
| UniProt Code: | Q8NFT8 |
| NCBI GenInfo Identifier: | 74730301 |
| NCBI Gene ID: | 92737 |
| NCBI Accession: | Q8NFT8.1 |
| UniProt Secondary Accession: | Q8NFT8,Q53R88, Q53TP7, Q53TQ5, Q8IYT0, Q8TB42, Q9NTF1 Q9UDM2, A6NP39, |
| UniProt Related Accession: | Q8NFT8 |
| Molecular Weight: | 78,475 Da |
| NCBI Full Name: | Delta and Notch-like epidermal growth factor-related receptor |
| NCBI Synonym Full Names: | delta/notch like EGF repeat containing |
| NCBI Official Symbol: | DNER |
| NCBI Official Synonym Symbols: | bet; UNQ26 |
| NCBI Protein Information: | delta and Notch-like epidermal growth factor-related receptor |
| UniProt Protein Name: | Delta and Notch-like epidermal growth factor-related receptor |
| Protein Family: | Delta and Notch-like epidermal growth factor-related receptor |
| UniProt Gene Name: | DNER |
| UniProt Entry Name: | DNER_HUMAN |
 | Western blot analysis of extracts of various cell lines, using DNER antibody (CAB15551) at 1:1000 dilution. Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) (CABS014) at 1:10000 dilution. Lysates/proteins: 25ug per lane. Blocking buffer: 3% nonfat dry milk in TBST. Detection: ECL Basic Kit (RM00020). Exposure time: 10s. |
 | Immunofluorescence analysis of L929 cells using DNER antibody (CAB15551) at dilution of 1:100. Blue: DAPI for nuclear staining. |
View AllClose
Related Products
Human DNER PharmaGenie ELISA Kit (SBRS0504)
system_update_altDatasheetHuman DNER PharmaGenie ELISA Kit (SBRS0504)Overview
Human anti-EPO antibody(anti-Erythropoietin antibody) ELISA Kit
system_update_altDatasheet - तकनीकी मैनुअलsystem_update_altMSDS - तकनीक
Human Anti-DSG3 antibody(anti-Desmoglein-3 antibody) ELISA Kit
system_update_altDatasheet - तकनीकी मैनुअलsystem_update_altMSDS - तकनीक