Cell Biology Antibodies 15
Anti-DNAJC15 Antibody (CAB4825)
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- SKU:
- CAB4825
- Product Type:
- Antibody
- Antibody Type:
- Monoclonal Antibody
- Reactivity:
- Human
- Reactivity:
- Mouse
- Reactivity:
- Rat
- Host Species:
- Rabbit
- Isotype:
- IgG
- Synonyms:
- DNAJD1
- Synonyms:
- HSD18
- Synonyms:
- MCJ
- Research Area:
- Cell Biology
Description
| Product Name: | DNAJC15 Rabbit mAb |
| Product Code: | CAB4825 |
| Size: | 20uL, 50uL, 100uL |
| Synonyms: | DNAJD1, HSD18, MCJ |
| Applications: | WB, IF |
| Reactivity: | Human, Mouse, Rat |
| Host Species: | Rabbit |
| Immunogen: | A synthesized peptide derived from human DNAJC15 |
| Applications: | WB, IF |
| Recommended Dilutions: | WB 1:500 - 1:2000 IF 1:50 - 1:200 |
| Reactivity: | Human, Mouse, Rat |
| Positive Samples: | 293T, Mouse testis, Mouse brain, Mouse kidney, Rat testis, Rat brain |
| Immunogen: | A synthesized peptide derived from human DNAJC15 |
| Purification Method: | Affinity purification |
| Storage: | Store at -20°C. Avoid freeze / thaw cycles. Buffer: PBS with 0.02% sodium azide, 0.05% BSA, 50% glycerol, pH7.3. |
| Isotype: | IgG |
| Sequence: | Email for sequence |
| Gene ID: | 29103 |
| Uniprot: | Q9Y5T4 |
| Calculated MW: | 16kDa |
| Observed MW: | 18KDa |
| UniProt Protein Function: | DNAJC15: Negative regulator of the mitochondrial respiratory chain. Prevents mitochondrial hyperpolarization state and restricts mitochondrial generation of ATP. Acts as an import component of the TIM23 translocase complex. Stimulates the ATPase activity of HSPA9. Interacts with the TIM23 complex. Directly interacts with PAM16/MAGMAS; this interaction counteracts DNAJC15-dependent stimulation of HSPA9 ATPase activity. Associates with complex I of the mitochondrial electron transfer chain; this interaction may interfere with the formation of supercomplexes that facilitate the transfer of electrons between complexes |
| UniProt Protein Details: | Protein type:Chaperone; Membrane protein, integral; Cell adhesion; Mitochondrial Chromosomal Location of Human Ortholog: 13q14.1 Cellular Component: mitochondrial inner membrane; integral to membrane Biological Process: protein transport; regulation of lipid metabolic process; cellular response to starvation; negative regulation of protein complex assembly |
| UniProt Code: | Q9Y5T4 |
| NCBI GenInfo Identifier: | 110808202 |
| NCBI Gene ID: | 29103 |
| NCBI Accession: | Q9Y5T4.2 |
| UniProt Secondary Accession: | Q9Y5T4,Q5T219, Q6X963, B2R4L0, |
| UniProt Related Accession: | Q9Y5T4 |
| Molecular Weight: | 16,383 Da |
| NCBI Full Name: | DnaJ homolog subfamily C member 15 |
| NCBI Synonym Full Names: | DnaJ (Hsp40) homolog, subfamily C, member 15 |
| NCBI Official Symbol: | DNAJC15 |
| NCBI Official Synonym Symbols: | MCJ; HSD18; DNAJD1 |
| NCBI Protein Information: | dnaJ homolog subfamily C member 15; DNAJ domain-containing; DnaJ (Hsp40) homolog, subfamily D, member 1; cell growth-inhibiting gene 22 protein; methylation-controlled J protein |
| UniProt Protein Name: | DnaJ homolog subfamily C member 15 |
| UniProt Synonym Protein Names: | Cell growth-inhibiting gene 22 protein; Methylation-controlled J protein; MCJ |
| Protein Family: | DnaJ homolog subfamily |
| UniProt Gene Name: | DNAJC15 |
| UniProt Entry Name: | DJC15_HUMAN |
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