Signal Transduction Antibodies 3

Anti-DNAJB9 Antibody (CAB7494)

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SKU:
CAB7494
Product Type:
Antibody
Reactivity:
Mouse
Reactivity:
Rat
Host Species:
Rabbit
Isotype:
IgG
Antibody Type:
Polyclonal Antibody
Research Area:
Signal Transduction

Description

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Antibody Name:Anti-DNAJB9 Antibody
Antibody SKU:CAB7494
Antibody Size:20uL, 50uL, 100uL
Application:WB
Reactivity:Mouse, Rat
Host Species:Rabbit
Immunogen:Recombinant fusion protein containing a sequence corresponding to amino acids 24-223 of human DNAJB9 (NP_036460.1).
Application:WB
Recommended Dilution:WB 1:500 - 1:2000
Reactivity:Mouse, Rat
Positive Samples:Mouse liver, Rat liver
Immunogen:Recombinant fusion protein containing a sequence corresponding to amino acids 24-223 of human DNAJB9 (NP_036460.1).
Purification Method:Affinity purification
Storage Buffer:Store at -20'C. Avoid freeze / thaw cycles. Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3.
Isotype:IgG
Sequence:SKSY YDIL GVPK SASE RQIK KAFH KLAM KYHP DKNK SPDA EAKF REIA EAYE TLSD ANRR KEYD TLGH SAFT SGKG QRGS GSSF EQSF NFNF DDLF KDFG FFGQ NQNT GSKK RFEN HFQT RQDG GSSR QRHH FQEF SFGG GLFD DMFE DMEK MFSF SGFD STNQ HTVQ TENR FHGS SKHC RTVT QRRG NMVT TYTD CSGQ
Gene ID:4189
Uniprot:Q9UBS3
Cellular Location:Endoplasmic reticulum lumen
Calculated MW:25kDa
Observed MW:25kDa
Synonyms:DNAJB9, ERdj4, MDG-1, MDG1, MST049, MSTP049
Background:This gene is a member of the J protein family. J proteins function in many cellular processes by regulating the ATPase activity of 70 kDa heat shock proteins. This gene is a member of the type 2 subgroup of DnaJ proteins. The encoded protein is localized to the endoplasmic reticulum. This protein is induced by endoplasmic reticulum stress and plays a role in protecting stressed cells from apoptosis.
UniProt Protein Function:DNAJB9: Acts as a co-chaperone with an Hsp70 protein.
UniProt Protein Details:

Protein type:Endoplasmic reticulum; Chaperone

Chromosomal Location of Human Ortholog: 7q31|14q24.2-q24.3

Cellular Component: cytoplasm; endoplasmic reticulum; endoplasmic reticulum membrane; nucleolus

Molecular Function:misfolded protein binding; protein binding

Biological Process: ER-associated protein catabolic process

NCBI Summary:This gene is a member of the J protein family. J proteins function in many cellular processes by regulating the ATPase activity of 70 kDa heat shock proteins. This gene is a member of the type 2 subgroup of DnaJ proteins. The encoded protein is localized to the endoplasmic reticulum. This protein is induced by endoplasmic reticulum stress and plays a role in protecting stressed cells from apoptosis. [provided by RefSeq, Dec 2010]
UniProt Code:Q9UBS3
NCBI GenInfo Identifier:18203496
NCBI Gene ID:4189
NCBI Accession:Q9UBS3.1
UniProt Related Accession:Q9UBS3
Molecular Weight:25,518 Da
NCBI Full Name:DnaJ homolog subfamily B member 9
NCBI Synonym Full Names:DnaJ heat shock protein family (Hsp40) member B9
NCBI Official Symbol:DNAJB9  
NCBI Official Synonym Symbols:MDG1; ERdj4; MDG-1; MST049; MSTP049  
NCBI Protein Information:dnaJ homolog subfamily B member 9
UniProt Protein Name:DnaJ homolog subfamily B member 9
UniProt Synonym Protein Names:Endoplasmic reticulum DNA J domain-containing protein 4; ER-resident protein ERdj4; ERdj4; Microvascular endothelial differentiation gene 1 protein; Mdg-1
Protein Family:DnaJ homolog subfamily
UniProt Gene Name:DNAJB9  
UniProt Entry Name:DNJB9_HUMAN
Anti-DNAJB9 Antibody (CAB7494)Western blot analysis of extracts of various cell lines, using DNAJB9 antibody (CAB7494) at 1:1000 dilution. Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) (CABS014) at 1:10000 dilution. Lysates/proteins: 25ug per lane. Blocking buffer: 3% nonfat dry milk in TBST. Detection: ECL Basic Kit (RM00020). Exposure time: 10s.
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