Cell Biology Antibodies 4

Anti-DMKN Antibody (CAB13871)

(No reviews yet) Write a Review
SKU:
CAB13871
Product Type:
Antibody
Reactivity:
Human
Reactivity:
Rat
Host Species:
Rabbit
Isotype:
IgG
Antibody Type:
Polyclonal Antibody
Research Area:
Cell Biology

Description

system_update_altDatasheetsystem_update_altMSDS
Antibody Name:Anti-DMKN Antibody
Antibody SKU:CAB13871
Antibody Size:20uL, 50uL, 100uL
Application:WB
Reactivity:Human, Rat
Host Species:Rabbit
Immunogen:Recombinant fusion protein containing a sequence corresponding to amino acids 355-449 of human DMKN (NP_001177276.1).
Application:WB
Recommended Dilution:WB 1:500 - 1:2000
Reactivity:Human, Rat
Positive Samples:Rat lung
Immunogen:Recombinant fusion protein containing a sequence corresponding to amino acids 355-449 of human DMKN (NP_001177276.1).
Purification Method:Affinity purification
Storage Buffer:Store at -20'C. Avoid freeze / thaw cycles. Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3.
Isotype:IgG
Sequence:WEDF KQNT PFLN WKAI IEGA DASS LQKR AGRA DQPG AGWQ EVAA VTSK NYNY NQHA YPTA YGGK YSVK TPAK GGVS PSSS ASRV QPGL LQWV KFW
Gene ID:93099
Uniprot:Q6E0U4
Cellular Location:Secreted
Calculated MW:9kDa/14-20kDa/35-47kDa
Observed MW:47kDa
Synonyms:DMKN, UNQ729, ZD52F10, dermokine
Background:This gene is upregulated in inflammatory diseases, and it was first observed as expressed in the differentiated layers of skin. The most interesting aspect of this gene is the differential use of promoters and terminators to generate isoforms with unique cellular distributions and domain components. Alternatively spliced transcript variants encoding different isoforms have been identified for this gene.
UniProt Protein Function:DMKN: May act as a soluble regulator of keratinocyte differentiation (Potential). Belongs to the dermokine family. 15 isoforms of the human protein are produced by alternative splicing.
UniProt Protein Details:

Protein type:Secreted; Secreted, signal peptide

Chromosomal Location of Human Ortholog: 19q13.12

Cellular Component: extracellular space

Molecular Function:protein binding

NCBI Summary:This gene is upregulated in inflammatory diseases, and it was first observed as expressed in the differentiated layers of skin. The most interesting aspect of this gene is the differential use of promoters and terminators to generate isoforms with unique cellular distributions and domain components. Alternatively spliced transcript variants encoding different isoforms have been identified for this gene. [provided by RefSeq, Jun 2010]
UniProt Code:Q6E0U4
NCBI GenInfo Identifier:290457677
NCBI Gene ID:93099
NCBI Accession:Q6E0U4.3
UniProt Secondary Accession:Q6E0U4,Q32W58, Q32W62, Q32W63, A3EZ79, A3EZ80, A3EZ81 A3EZ82, A3EZ83, C9J4P6, C9J5N8, C9JAL3,
UniProt Related Accession:Q6E0U4
Molecular Weight:46,944 Da
NCBI Full Name:Dermokine
NCBI Synonym Full Names:dermokine
NCBI Official Symbol:DMKN  
NCBI Official Synonym Symbols:UNQ729; ZD52F10  
NCBI Protein Information:dermokine; epidermis-specific secreted protein SK30/SK89
UniProt Protein Name:Dermokine
UniProt Synonym Protein Names:Epidermis-specific secreted protein SK30/SK89
Protein Family:Dermokine
UniProt Gene Name:DMKN  
UniProt Entry Name:DMKN_HUMAN
Anti-DMKN Antibody (CAB13871)Western blot analysis of extracts of rat ovary, using DMKN antibody (CAB13871) at 1:3000 dilution. Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) (CABS014) at 1:10000 dilution. Lysates/proteins: 25ug per lane. Blocking buffer: 3% nonfat dry milk in TBST. Detection: ECL Basic Kit (RM00020). Exposure time: 1s.
View AllClose

0 Reviews

View AllClose

Related Products