Cell Biology Antibodies 14

Anti-DLG3 Antibody (CAB16831)

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SKU:
CAB16831
Product Type:
Antibody
Reactivity:
Human
Reactivity:
Mouse
Reactivity:
Rat
Host Species:
Rabbit
Isotype:
IgG
Antibody Type:
Polyclonal Antibody
Research Area:
Cell Biology

Description

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Antibody Name:Anti-DLG3 Antibody
Antibody SKU:CAB16831
Antibody Size:20uL, 50uL, 100uL
Application:WB IHC
Reactivity:Human, Mouse, Rat
Host Species:Rabbit
Immunogen:Recombinant fusion protein containing a sequence corresponding to amino acids 464-817 of human DLG3 (NP_066943.2).
Application:WB IHC
Recommended Dilution:WB 1:500 - 1:2000 IHC 1:100 - 1:200
Reactivity:Human, Mouse, Rat
Positive Samples:293T, K-562, Mouse brain, Rat brain
Immunogen:Recombinant fusion protein containing a sequence corresponding to amino acids 464-817 of human DLG3 (NP_066943.2).
Purification Method:Affinity purification
Storage Buffer:Store at -20°C. Avoid freeze / thaw cycles. Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3.
Isotype:IgG
Sequence:QYRP EEYS RFES KIHD LREQ MMNS SMSS GSGS LRTS EKRS LYVR ALFD YDRT RDSC LPSQ GLSF SYGD ILHV INAS DDEW WQAR LVTP HGES EQIG VIPS KKRV EKKE RARL KTVK FHAR TGMI ESNR DFPG LSDD YYGA KNLK GQED AILS YEPV TRQE IHYA RPVI ILGP MKDR VNDD LISE FPHK FGSC VPHT TRPR RDNE VDGQ DYHF VVSR EQME KDIQ DNKF IEAG QFND NLYG TSIQ SVRA VAER GKHC ILDV SGNA IKRL QQAQ LYPI AIFI KPKS IEAL MEMN RRQT YEQA NKIY DKAM KLEQ EFGE YFTA IVQG DSLE EIYN KIKQ IIED QSGH YIWV PSPE KL
Gene ID:1741
Uniprot:Q92796
Cellular Location:
Calculated MW:42kDa/57kDa/90kDa
Observed MW:110kDa/115kDa
Anti-DLG3 Antibody (CAB16831)Western blot - DLG3 Rabbit pAb (CAB16831)
Synonyms:DLG3, MRX, MRX90, NEDLG, PPP1R82, SAP102, XLMR
Background:This gene encodes a member of the membrane-associated guanylate kinase protein family. The encoded protein may play a role in clustering of NMDA receptors at excitatory synapses. It may also negatively regulate cell proliferation through interaction with the C-terminal region of the adenomatosis polyposis coli tumor suppressor protein. Mutations in this gene have been associated with X-linked mental retardation. Alternatively spliced transcript variants have been described.
UniProt Protein Function:Required for learning most likely through its role in synaptic plasticity following NMDA receptor signaling.
NCBI Summary:This gene encodes a member of the membrane-associated guanylate kinase protein family. The encoded protein may play a role in clustering of NMDA receptors at excitatory synapses. It may also negatively regulate cell proliferation through interaction with the C-terminal region of the adenomatosis polyposis coli tumor suppressor protein. Mutations in this gene have been associated with X-linked mental retardation. Alternatively spliced transcript variants have been described. [provided by RefSeq, Oct 2009]
UniProt Code:Q92796
NCBI GenInfo Identifier:119943106
NCBI Gene ID:1741
NCBI Accession:NP_066943
UniProt Secondary Accession:Q92796,Q5JUW6, Q5JUW7, Q9ULI8, B4E0H1, D3DVU5,
UniProt Related Accession:Q92796
Molecular Weight:42,112 Da
NCBI Full Name:disks large homolog 3 isoform a
NCBI Synonym Full Names:discs, large homolog 3 (Drosophila)
NCBI Official Symbol:DLG3  
NCBI Official Synonym Symbols:MRX; XLMR; MRX90; NEDLG; SAP102; PPP1R82  
NCBI Protein Information:disks large homolog 3
UniProt Protein Name:Disks large homolog 3
UniProt Synonym Protein Names:Neuroendocrine-DLG; Synapse-associated protein 102; SAP-102; SAP102; XLMR
Protein Family:Disks large
UniProt Gene Name:DLG3  
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