Anti-DKK1 Recombinant Rabbit Monoclonal Antibody (HDAB0201)
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- SKU:
- HDAB0201
- Product Type:
- Rabbit Monoclonal Antibody
- Antibody Type:
- Monoclonal Antibody
- Size:
- 100 μg
- Reactivity:
- Human
- Host Species:
- Rabbit
- Antibody Isotype:
- Rabbit Igg
- Clone:
- DM210
- Synonyms:
- DKK-1, SK
Description
system_update_altDatasheet
| SKU: | HDAB0201 |
| Size: | 100 µg |
| Clonality: | Monoclonal |
| Clone: | DM210 |
| Synonyms: | DKK-1, SK |
| Applications: | ELISA, Flow Cyt |
| Recommended Dilution: | ELISA 1:5000-10000; Flow Cyt 1:100 |
| Host Species: | Rabbit |
| Isotype: | Rabbit IgG |
| Reactivity: | Human |
| Purification Method: | Purified from cell culture supernatant by affinity chromatography |
| Formulation: | Powder |
| Buffer: | 1XPBS |
| Storage: | Store at -20°C to -80°C for 12 months in lyophilized form. After reconstitution, if not intended for use within a month, aliquot and store at -80°C (Avoid repeated freezing and thawing).Lyophilized antibodies are shipped at ambient temperature. |
| Usage: | Research use only |
| Background: | This gene encodes a member of the dickkopf family of proteins. Members of this family are secreted proteins characterized by two cysteine-rich domains that mediate protein-protein interactions. The encoded protein binds to the LRP6 co-receptor and inhibits beta-catenin-dependent Wnt signaling. This gene plays a role in embryonic development and may be important in bone formation in adults. Elevated expression of this gene has been observed in numerous human cancers and this protein may promote proliferation, invasion and growth in cancer cell lines. |
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