Cell Biology Antibodies 13

Anti-DHX29 Antibody (CAB17709)

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SKU:
CAB17709
Product Type:
Antibody
Reactivity:
Human
Host Species:
Rabbit
Isotype:
IgG
Antibody Type:
Polyclonal Antibody
Research Area:
Cell Biology

Description

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Antibody Name:Anti-DHX29 Antibody
Antibody SKU:CAB17709
Antibody Size:20uL, 50uL, 100uL
Application:WB
Reactivity:Human
Host Species:Rabbit
Immunogen:Recombinant fusion protein containing a sequence corresponding to amino acids 1020-1369 of human DHX29 (NP_061903.2).
Application:WB
Recommended Dilution:WB 1:500 - 1:2000
Reactivity:Human
Positive Samples:HepG2
Immunogen:Recombinant fusion protein containing a sequence corresponding to amino acids 1020-1369 of human DHX29 (NP_061903.2).
Purification Method:Affinity purification
Storage Buffer:Store at -20°C. Avoid freeze / thaw cycles. Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3.
Isotype:IgG
Sequence:LHIM KCNL GSPE DFLS KALD PPQL QVIS NAMN LLRK IGAC ELNE PKLT PLGQ HLAA LPVN VKIG KMLI FGAI FGCL DPVA TLAA VMTE KSPF TTPI GRKD EADL AKSA LAMA DSDH LTIY NAYL GWKK ARQE GGYR SEIT YCRR NFLN RTSL LTLE DVKQ ELIK LVKA AGFS SSTT STSW EGNR ASQT LSFQ EIAL LKAV LVAG LYDN VGKI IYTK SVDV TEKL ACIV ETAQ GKAQ VHPS SVNR DLQT HGWL LYQE KIRY ARVY LRET TLIT PFPV LLFG GDIE VQHR ERLL SIDG WIYF QAPV KIAV IFKQ LRVL IDSV LRKK LENP KMSL ENDK ILQI ITEL IKTE NN
Gene ID:54505
Uniprot:Q7Z478
Cellular Location:
Calculated MW:155kDa
Observed MW:155kDa
Anti-DHX29 Antibody (CAB17709)Western blot - DHX29 Polyclonal Antibody (CAB17709)
Synonyms:DDX29, DHX29
Background:This gene encodes a member of the DEAH (Asp-Glu-Ala-His) subfamily of proteins, part of the DEAD (Asp-Glu-Ala-Asp) box family of RNA helicases. The encoded protein functions in translation initiation, and is specifically required for ribosomal scanning across stable mRNA secondary structures during initiation codon selection. This protein may also play a role in sensing virally derived cytosolic nucleic acids. Knockdown of this gene results in reduced protein translation and impaired proliferation of cancer cells. [provided by RefSeq, Sep 2016]
UniProt Protein Function:DDX29: ATP-binding RNA helicase involved in translation initiation. Required for efficient initiation on mammalian mRNAs with structured 5'-UTRs by promoting efficient NTPase-dependent 48S complex formation. Specifically binds to the 40S ribosome near the mRNA entrance. Does not possess a processive helicase activity. Belongs to the DEAD box helicase family. DEAH subfamily.
UniProt Protein Details:

Protein type:Translation; Helicase; EC 3.6.4.13

Chromosomal Location of Human Ortholog: 5q11.2

Cellular Component: mitochondrion; nucleus

Molecular Function:translation initiation factor activity; ATP binding; ATP-dependent RNA helicase activity; ribosomal small subunit binding

Biological Process: RNA processing; translational initiation

UniProt Code:Q7Z478
NCBI GenInfo Identifier:67782361
NCBI Gene ID:54505
NCBI Accession:NP_061903.2
UniProt Secondary Accession:Q7Z478,O75549, Q63HN0, Q63HN3, Q8IWW2, Q8N3A1, Q9UMH2
UniProt Related Accession:Q7Z478
Molecular Weight:155,236 Da
NCBI Full Name:Homo sapiens DEAH (Asp-Glu-Ala-His) box polypeptide 29 (DHX29), mRNA
NCBI Synonym Full Names:DEAH (Asp-Glu-Ala-His) box polypeptide 29
NCBI Official Symbol:DHX29  
NCBI Official Synonym Symbols:DDX29  
NCBI Protein Information:ATP-dependent RNA helicase DHX29; DEAD/H (Asp-Glu-Ala-Asp/His) box polypeptide 29; DEAH box protein 29; nucleic acid helicase DDXx
UniProt Protein Name:ATP-dependent RNA helicase DHX29
UniProt Synonym Protein Names:DEAH box protein 29; Nucleic acid helicase DDXx
Protein Family:ATP-dependent RNA helicase
UniProt Gene Name:DHX29  
UniProt Entry Name:DHX29_HUMAN
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