Cell Biology Antibodies 5

Anti-DGCR6L Antibody (CAB15202)

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SKU:
CAB15202
Product Type:
Antibody
Reactivity:
Human
Reactivity:
Mouse
Reactivity:
Rat
Host Species:
Rabbit
Isotype:
IgG
Antibody Type:
Polyclonal Antibody
Research Area:
Cell Biology

Description

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Antibody Name:Anti-DGCR6L Antibody
Antibody SKU:CAB15202
Antibody Size:20uL, 50uL, 100uL
Application:WB
Reactivity:Human, Mouse, Rat
Host Species:Rabbit
Immunogen:Recombinant fusion protein containing a sequence corresponding to amino acids 1-220 of human DGCR6L (NP_150282.2).
Application:WB
Recommended Dilution:WB 1:500 - 1:2000
Reactivity:Human, Mouse, Rat
Positive Samples:Mouse liver, Rat liver
Immunogen:Recombinant fusion protein containing a sequence corresponding to amino acids 1-220 of human DGCR6L (NP_150282.2).
Purification Method:Affinity purification
Storage Buffer:Store at -20'C. Avoid freeze / thaw cycles. Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3.
Isotype:IgG
Sequence:MERY AAAL EEVA DGAR QQER HYQL LSAL QSLV KELP SSFQ QRLS YTTL SDLA LALL DGTV FEIV QGLL EIQH LTEK SLYN QRLR LQNE HRVL RQAL RQKH QEAQ QACR PHNL PVVQ AAQQ RELE AVEH RIRE EQRA MDQK IILE LDRK VADQ QSTL EKAG VAGF YVTT NPQE LMLQ MNLL ELIR KLQQ RGCR AGNA ALGL GGPW QSPA AQCD QKGS PVPP
Gene ID:85359
Uniprot:Q9BY27
Cellular Location:Nucleus
Calculated MW:24kDa
Observed MW:25kDa
Synonyms:DGCR6L, DGCR6
Background:This gene, the result of a duplication at this locus, is one of two functional genes encoding nearly identical proteins that have similar expression patterns. The product of this gene is a protein that shares homology with the Drosophila gonadal protein, expressed in gonadal tissues and germ cells, and with the human laminin gamma-1 chain that functions in cell attachment and migration. This gene is located in a region of chromosome 22 implicated in the DiGeorge syndrome, one facet of a broader collection of anomalies referred to as the CATCH 22 syndrome.
UniProt Protein Function:DGCR6L: May play a role in neural crest cell migration into the third and fourth pharyngeal pouches. Belongs to the gonadal family.
UniProt Protein Details:

Chromosomal Location of Human Ortholog: 22q11.21

Molecular Function:protein binding

NCBI Summary:This gene, the result of a duplication at this locus, is one of two functional genes encoding nearly identical proteins that have similar expression patterns. The product of this gene is a protein that shares homology with the Drosophila gonadal protein, expressed in gonadal tissues and germ cells, and with the human laminin gamma-1 chain that functions in cell attachment and migration. This gene is located in a region of chromosome 22 implicated in the DiGeorge syndrome, one facet of a broader collection of anomalies referred to as the CATCH 22 syndrome. [provided by RefSeq, Jul 2008]
UniProt Code:Q9BY27
NCBI GenInfo Identifier:22001579
NCBI Gene ID:85359
NCBI Accession:Q9BY27.2
UniProt Secondary Accession:Q9BY27,Q9BW33, A8K1N7, B3KMC0, D3DX29,
UniProt Related Accession:Q9BY27
Molecular Weight:24,932 Da
NCBI Full Name:Protein DGCR6L
NCBI Synonym Full Names:DiGeorge syndrome critical region gene 6-like
NCBI Official Symbol:DGCR6L  
NCBI Official Synonym Symbols:DGCR6  
NCBI Protein Information:protein DGCR6L
UniProt Protein Name:Protein DGCR6L
UniProt Synonym Protein Names:DiGeorge syndrome critical region 6-like protein
Protein Family:Protein
UniProt Gene Name:DGCR6L  
UniProt Entry Name:DGC6L_HUMAN
Anti-DGCR6L Antibody (CAB15202)Western blot analysis of extracts of various cell lines, using DGCR6L antibody (CAB15202) at 1:1000 dilution. Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) (CABS014) at 1:10000 dilution. Lysates/proteins: 25ug per lane. Blocking buffer: 3% nonfat dry milk in TBST. Detection: ECL Basic Kit (RM00020). Exposure time: 30s.
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