Cell Biology Antibodies 12

Anti-DEPDC6 Antibody (CAB9447)

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SKU:
CAB9447
Product Type:
Antibody
Applications:
WB
Reactivity:
Human
Reactivity:
Mouse
Host Species:
Rabbit
Isotype:
IgG
Research Area:
Cell Biology

Description

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Antibody Name:Anti-DEPDC6 Antibody
Antibody SKU:CAB9447
Antibody Size:20uL, 50uL, 100uL
Application:WB
Reactivity:Human, Mouse
Host Species:Rabbit
Immunogen:Recombinant fusion protein containing a sequence corresponding to amino acids 1-220 of human DEPDC6 (NP_073620.2).
Application:WB
Recommended Dilution:WB 1:500 - 1:2000
Reactivity:Human, Mouse
Positive Samples:HeLa, HepG2, MCF7
Immunogen:Recombinant fusion protein containing a sequence corresponding to amino acids 1-220 of human DEPDC6 (NP_073620.2).
Purification Method:Affinity purification
Storage Buffer:Store at -20'C. Avoid freeze / thaw cycles. Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3.
Isotype:IgG
Sequence:MEEG GSTG SAGS DSST SGSG GAQQ RELE RMAE VLVT GEQL RLRL HEEK VIKD RRHH LKTY PNCF VAKE LIDW LIEH KEAS DRET AIKL MQKL ADRG IIHH VCDE HKEF KDVK LFYR FRKD DGTF PLDN EVKA FMRG QRLY EKLM SPEN TLLQ PREE EGVK YERT FMAS EFLD WLVQ EGEA TTRK EAEQ LCHR LMEH GIIQ HVSN KHPF VDSN LLYQ FRMN
Gene ID:64798
Uniprot:Q8TB45
Cellular Location:
Calculated MW:34kDa/46kDa
Observed MW:48KDa
Synonyms:DEPTOR, DEP.6, DEPDC6
Background:
UniProt Protein Function:DEPTOR: Negative regulator of the mTORC1 and mTORC2 signaling pathways. Inhibits the kinase activity of both complexes.
UniProt Protein Details:

Protein type:Apoptosis

Chromosomal Location of Human Ortholog: 8q24.12

Cellular Component: cytoplasm; intracellular

Molecular Function:protein binding

Biological Process: negative regulation of cell size; negative regulation of protein kinase activity; negative regulation of TOR signaling pathway

UniProt Code:Q8TB45
NCBI GenInfo Identifier:251757257
NCBI Gene ID:64798
NCBI Accession:Q8TB45.2
UniProt Secondary Accession:Q8TB45,Q96EQ1, Q9H0R7, Q9H894, Q9HA07, B2RCL9, B4DN97 E7EV87,
UniProt Related Accession:Q8TB45
Molecular Weight:34,006 Da
NCBI Full Name:DEP domain-containing mTOR-interacting protein
NCBI Synonym Full Names:DEP domain containing MTOR interacting protein
NCBI Official Symbol:DEPTOR  
NCBI Official Synonym Symbols:DEP.6; DEPDC6  
NCBI Protein Information:DEP domain-containing mTOR-interacting protein
UniProt Protein Name:DEP domain-containing mTOR-interacting protein
UniProt Synonym Protein Names:DEP domain-containing protein 6
Protein Family:DEP domain-containing mTOR-interacting protein
UniProt Gene Name:DEPTOR  
Anti-DEPDC6 Polyclonal Antibody (CAB9447)Western blot analysis of extracts of various cell lines, using DEPDC6 Rabbit pAb (CAB9447) at 1:1000 dilution. Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) (CABS014) at 1:10000 dilution. Lysates/proteins: 25ug per lane. Blocking buffer: 3% nonfat dry milk in TBST. Detection: ECL Basic Kit (RM00020). Exposure time: 60s.
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