Metabolism Antibodies 1
Anti-DENR Antibody (CAB13699)
(No reviews yet)
Write a Review
- SKU:
- CAB13699
- Product Type:
- Antibody
- Reactivity:
- Human
- Reactivity:
- Mouse
- Reactivity:
- Rat
- Host Species:
- Rabbit
- Isotype:
- IgG
- Antibody Type:
- Polyclonal Antibody
- Research Area:
- Metabolism
Description
| Antibody Name: | Anti-DENR Antibody |
| Antibody SKU: | CAB13699 |
| Antibody Size: | 20uL, 50uL, 100uL |
| Application: | WB IHC |
| Reactivity: | Human, Mouse, Rat |
| Host Species: | Rabbit |
| Immunogen: | Recombinant fusion protein containing a sequence corresponding to amino acids 1-198 of human DENR (NP_003668.2). |
| Application: | WB IHC |
| Recommended Dilution: | WB 1:500 - 1:2000 IHC 1:50 - 1:200 |
| Reactivity: | Human, Mouse, Rat |
| Positive Samples: | U-87MG, BxPC-3, HeLa, Jurkat, Mouse heart, Rat lung |
| Immunogen: | Recombinant fusion protein containing a sequence corresponding to amino acids 1-198 of human DENR (NP_003668.2). |
| Purification Method: | Affinity purification |
| Storage Buffer: | Store at -20'C. Avoid freeze / thaw cycles. Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3. |
| Isotype: | IgG |
| Sequence: | MAAD ISES SGAD CKGD PRNS AKLD ADYP LRVL YCGV CSLP TEYC EYMP DVAK CRQW LEKN FPNE FAKL TVEN SPKQ EAGI SEGQ GTAG EEEE KKKQ KRGG RGQI KQKK KTVP QKVT IAKI PRAK KKYV TRVC GLAT FEID LKEA QRFF AQKF SCGA SVTG EDEI IIQG DFTD DIID VIQE KWPE VDDD SIED LGEV KK |
| Gene ID: | 8562 |
| Uniprot: | O43583 |
| Cellular Location: | |
| Calculated MW: | 22kDa |
| Observed MW: | 30kDa |
| Synonyms: | DENR, DRP, DRP1, SMAP-3 |
| Background: | This gene encodes a protein whose expression was found to increase in cultured cells at high density but not during growth arrest. This gene was also shown to have increased expression in cells overexpressing HER-2/neu proto-oncogene. The protein contains an SUI1 domain. In budding yeast, SUI1 is a translation initiation factor that along with eIF-2 and the initiator tRNA-Met, directs the ribosome to the proper translation start site. Proteins similar to SUI have been found in mammals, insects, and plants. |
| UniProt Protein Function: | DENR: May be involved in the translation of target mRNAs by scanning and recognition of the initiation codon. Plays a role in the modulation of the translational profile of a subset of cancer- related mRNAs when recruited to the translational initiation complex by the oncogene MCTS1. Belongs to the DENR family. |
| UniProt Protein Details: | Protein type:Translation; RNA-binding Chromosomal Location of Human Ortholog: 12q24.31 Molecular Function:protein binding; translation initiation factor activity Biological Process: ribosome disassembly; formation of translation preinitiation complex |
| NCBI Summary: | This gene encodes a protein whose expression was found to increase in cultured cells at high density but not during growth arrest. This gene was also shown to have increased expression in cells overexpressing HER-2/neu proto-oncogene. The protein contains an SUI1 domain. In budding yeast, SUI1 is a translation initiation factor that along with eIF-2 and the initiator tRNA-Met, directs the ribosome to the proper translation start site. Proteins similar to SUI have been found in mammals, insects, and plants. [provided by RefSeq, Jul 2008] |
| UniProt Code: | O43583 |
| NCBI GenInfo Identifier: | 13637727 |
| NCBI Gene ID: | 8562 |
| NCBI Accession: | O43583.2 |
| UniProt Secondary Accession: | O43583,Q9H3U6, Q9UKZ0, |
| UniProt Related Accession: | O43583 |
| Molecular Weight: | 198 |
| NCBI Full Name: | Density-regulated protein |
| NCBI Synonym Full Names: | density-regulated protein |
| NCBI Official Symbol: | DENR |
| NCBI Official Synonym Symbols: | DRP; DRP1; SMAP-3 |
| NCBI Protein Information: | density-regulated protein; smooth muscle cell associated protein-3; smooth muscle cell-associated protein 3 |
| UniProt Protein Name: | Density-regulated protein |
| UniProt Synonym Protein Names: | Protein DRP1; Smooth muscle cell-associated protein 3; SMAP-3 |
| Protein Family: | Density-regulated protein |
| UniProt Gene Name: | DENR |
| UniProt Entry Name: | DENR_HUMAN |
 | Western blot analysis of extracts of various cell lines, using DENR antibody (CAB13699) at 1:3000 dilution. Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) (CABS014) at 1:10000 dilution. Lysates/proteins: 25ug per lane. Blocking buffer: 3% nonfat dry milk in TBST. Detection: ECL Enhanced Kit (RM00021). Exposure time: 90s. |
 | Immunohistochemistry of paraffin-embedded rat heart using DENR antibody (CAB13699) at dilution of 1:150 (40x lens). |
View AllClose
Related Products
Human anti-EPO antibody(anti-Erythropoietin antibody) ELISA Kit
system_update_altDatasheet - तकनीकी मैनुअलsystem_update_altMSDS - तकनीक
Human Anti-DSG3 antibody(anti-Desmoglein-3 antibody) ELISA Kit
system_update_altDatasheet - तकनीकी मैनुअलsystem_update_altMSDS - तकनीक