Cell Biology Antibodies 2

Anti-DEFB132 Antibody (CAB1074)

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SKU:
CAB1074

Description

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Antibody Name:Anti-DEFB132 Antibody
Antibody SKU:CAB1074
Antibody Size:20uL, 50uL, 100uL
Application:WB
Reactivity:Mouse
Host Species:Rabbit
Immunogen:Recombinant fusion protein containing a sequence corresponding to amino acids 1-95 of human DEFB132 (NP_997352.1).
Application:WB
Recommended Dilution:WB 1:500 - 1:2000
Reactivity:Mouse
Positive Samples:Mouse testis, Mouse liver
Immunogen:Recombinant fusion protein containing a sequence corresponding to amino acids 1-95 of human DEFB132 (NP_997352.1).
Purification Method:Affinity purification
Storage Buffer:Store at -20'C. Avoid freeze / thaw cycles. Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3.
Isotype:IgG
Sequence:MKFL LLVL AALG FLTQ VIPA SAGG SKCV SNTP GYCR TCCH WGET ALFM CNAS RKCC ISYS FLPK PDLP QLIG NHWQ SRRR NTQR KDKK QQTT VTS
Gene ID:400830
Uniprot:Q7Z7B7
Cellular Location:Secreted
Calculated MW:10kDa
Observed MW:13kDa
Synonyms:DEFB132, BD-32, DEFB-32, DEFB32, HEL-75, KFLL827, UNQ827
Background:Defensins are cysteine-rich cationic polypeptides that are important in the immunologic response to invading microorganisms. The protein encoded by this gene is secreted and is a member of the beta defensin protein family. This protein binds spermatozoa and has antimicrobial activity against E. coli. Beta defensin genes are found in several clusters throughout the genome, with this gene mapping to a cluster at 20p13.
UniProt Protein Function:DEFB132: Has antibacterial activity (Potential). Belongs to the beta-defensin family.
UniProt Protein Details:

Protein type:Secreted, signal peptide; Secreted

Chromosomal Location of Human Ortholog: 20p13

Cellular Component: cell surface; extracellular region

Biological Process: defense response to bacterium; innate immune response

NCBI Summary:Defensins are cysteine-rich cationic polypeptides that are important in the immunologic response to invading microorganisms. The protein encoded by this gene is secreted and is a member of the beta defensin protein family. This protein binds spermatozoa and has antimicrobial activity against E. coli. Beta defensin genes are found in several clusters throughout the genome, with this gene mapping to a cluster at 20p13. [provided by RefSeq, Nov 2014]
UniProt Code:Q7Z7B7
NCBI GenInfo Identifier:61212742
NCBI Gene ID:400830
NCBI Accession:Q7Z7B7.1
UniProt Related Accession:Q7Z7B7
Molecular Weight:
NCBI Full Name:Beta-defensin 132
NCBI Synonym Full Names:defensin beta 132
NCBI Official Symbol:DEFB132  
NCBI Official Synonym Symbols:BD-32; DEFB32; HEL-75; UNQ827; DEFB-32; KFLL827  
NCBI Protein Information:beta-defensin 132
UniProt Protein Name:Beta-defensin 132
UniProt Synonym Protein Names:Beta-defensin 32; BD-32; DEFB-32; Defensin HEL-75; Defensin, beta 132
Protein Family:Beta-defensin
UniProt Gene Name:DEFB132  
UniProt Entry Name:DB132_HUMAN
Anti-DEFB132 Antibody (CAB1074)Western blot analysis of extracts of various cell lines, using DEFB132 antibody (CAB1074) at 1:1000 dilution. Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) (CABS014) at 1:10000 dilution. Lysates/proteins: 25ug per lane. Blocking buffer: 3% nonfat dry milk in TBST.
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Additional Information

Product Type:
Antibody
Reactivity:
Mouse
Host Species:
Rabbit
Isotype:
IgG
Antibody Type:
Polyclonal Antibody
Research Area:
Cell Biology
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