Cell Biology Antibodies 2
Anti-DEFB121 Antibody (CAB1208)
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- SKU:
- CAB1208
- Product Type:
- Antibody
- Reactivity:
- Human
- Reactivity:
- Mouse
- Reactivity:
- Rat
- Host Species:
- Rabbit
- Isotype:
- IgG
- Antibody Type:
- Polyclonal Antibody
- Research Area:
- Cell Biology
Description
| Antibody Name: | Anti-DEFB121 Antibody |
| Antibody SKU: | CAB1208 |
| Antibody Size: | 20uL, 50uL, 100uL |
| Application: | IHC IF |
| Reactivity: | Human, Mouse, Rat |
| Host Species: | Rabbit |
| Immunogen: | Recombinant fusion protein containing a sequence corresponding to amino acids 1-76 of human DEFB121 (NP_001011878.1). |
| Application: | IHC IF |
| Recommended Dilution: | IHC 1:50 - 1:100 IF 1:50 - 1:100 |
| Reactivity: | Human, Mouse, Rat |
| Positive Samples: |
| Immunogen: | Recombinant fusion protein containing a sequence corresponding to amino acids 1-76 of human DEFB121 (NP_001011878.1). |
| Purification Method: | Affinity purification |
| Storage Buffer: | Store at -20'C. Avoid freeze / thaw cycles. Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3. |
| Isotype: | IgG |
| Sequence: | MKLL LLLL TVTL LLAQ VTPV MKCW GKSG RCRT TCKE SEVY YILC KTEA KCCV DPKY VPVK PKLT DTNT SLES TSAV |
| Gene ID: | 245934 |
| Uniprot: | Q5J5C9 |
| Cellular Location: | Secreted |
| Calculated MW: | 8kDa |
| Observed MW: |
| Synonyms: | DEFB121, DEFB21, ESC42RELC |
| Background: | This gene encodes a member of the beta subfamily of defensins. Beta-defensins are antimicrobial peptides that protect tissues and organs from infection by a variety of microorganisms. This gene is found in a cluster with other beta-defensin genes on the long arm of chromosome 20. Two transcript variants encoding different isoforms have been found for this gene. |
| UniProt Protein Function: | DEFB121: Has antibacterial activity (Potential). Belongs to the beta-defensin family. |
| UniProt Protein Details: | Protein type:Secreted, signal peptide; Secreted Chromosomal Location of Human Ortholog: 20q11.21 Cellular Component: cell surface; extracellular region Biological Process: defense response to bacterium; innate immune response |
| NCBI Summary: | This gene encodes a member of the beta subfamily of defensins. Beta-defensins are antimicrobial peptides that protect tissues and organs from infection by a variety of microorganisms. This gene is found in a cluster with other beta-defensin genes on the long arm of chromosome 20. Two transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Nov 2014] |
| UniProt Code: | Q5J5C9 |
| NCBI GenInfo Identifier: | 61212937 |
| NCBI Gene ID: | 245934 |
| NCBI Accession: | Q5J5C9.1 |
| UniProt Related Accession: | Q5J5C9 |
| Molecular Weight: | ~ 8kDa |
| NCBI Full Name: | Beta-defensin 121 |
| NCBI Synonym Full Names: | defensin beta 121 |
| NCBI Official Symbol: | DEFB121 |
| NCBI Official Synonym Symbols: | DEFB21; ESC42RELC |
| NCBI Protein Information: | beta-defensin 121 |
| UniProt Protein Name: | Beta-defensin 121 |
| UniProt Synonym Protein Names: | Beta-defensin 21; DEFB-21; Defensin, beta 121 |
| Protein Family: | Beta-defensin |
| UniProt Gene Name: | DEFB121 |
| UniProt Entry Name: | DB121_HUMAN |
 | Immunohistochemistry of paraffin-embedded human prostate using DEFB121 antibody (CAB1208) at dilution of 1:100 (40x lens). |
 | Immunofluorescence analysis of rat testis cells using DEFB121 antibody (CAB1208) at dilution of 1:100. Blue: DAPI for nuclear staining. |
 | Immunofluorescence analysis of mouse testis cells using DEFB121 antibody (CAB1208) at dilution of 1:100. Blue: DAPI for nuclear staining. |
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