Cell Biology Antibodies 18

Anti-DEFA4 Antibody (CAB18358)

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SKU:
CAB18358
Product Type:
Antibody
Reactivity:
Rat
Host Species:
Rabbit
Isotype:
IgG
Research Area:
Cell Biology

Description

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Antibody Name:Anti-DEFA4 Antibody
Antibody SKU:CAB18358
Antibody Size:20uL, 50uL, 100uL
Application:WB
Reactivity:Rat
Host Species:Rabbit
Immunogen:Recombinant protein of human DEFA4.
Application:WB
Recommended Dilution:WB 1:500 - 1:2000
Reactivity:Rat
Positive Samples:
Immunogen:Recombinant protein of human DEFA4.
Purification Method:Affinity purification
Storage Buffer:Store at -20°C. Avoid freeze / thaw cycles. Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3.
Isotype:IgG
Sequence:Email for sequence
Gene ID:1669
Uniprot:P12838
Cellular Location:
Calculated MW:
Observed MW:Refer to figures
Synonyms:DEF4, HNP-4, HP-4, HP4, DEFA4
Background:
NCBI Summary:Defensins are a family of antimicrobial and cytotoxic peptides thought to be involved in host defense. They are abundant in the granules of neutrophils and also found in the epithelia of mucosal surfaces such as those of the intestine, respiratory tract, urinary tract, and vagina. Members of the defensin family are highly similar in protein sequence and distinguished by a conserved cysteine motif. Several alpha defensin genes are clustered on chromosome 8. This gene differs from other genes of this family by an extra 83-base segment that is apparently the result of a recent duplication within the coding region. The protein encoded by this gene, defensin, alpha 4, is found in the neutrophils; it exhibits corticostatic activity and inhibits corticotropin stimulated corticosterone production. [provided by RefSeq, Oct 2014]
UniProt Code:P12838
NCBI GenInfo Identifier:4503303
NCBI Gene ID:1669
NCBI Accession:NP_001916.1
UniProt Related Accession:P12838
Molecular Weight:~ 11kDa
NCBI Full Name:neutrophil defensin 4 preproprotein
NCBI Synonym Full Names:defensin alpha 4
NCBI Official Symbol:DEFA4  
NCBI Official Synonym Symbols:HP4; DEF4; HP-4; HNP-4  
NCBI Protein Information:neutrophil defensin 4
UniProt Protein Name:Neutrophil defensin 4
UniProt Synonym Protein Names:Defensin, alpha 4; HNP-4
Protein Family:Beta-carotene isomerase
UniProt Gene Name:DEFA4  
UniProt Entry Name:DEF4_HUMAN
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