Cell Biology Antibodies 13

Anti-DDX28 Antibody (CAB17728)

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SKU:
CAB17728
Product Type:
Antibody
Reactivity:
Human
Reactivity:
Mouse
Reactivity:
Rat
Host Species:
Rabbit
Isotype:
IgG
Antibody Type:
Polyclonal Antibody
Research Area:
Cell Biology

Description

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Antibody Name:Anti-DDX28 Antibody
Antibody SKU:CAB17728
Antibody Size:20uL, 50uL, 100uL
Application:WB
Reactivity:Human, Mouse, Rat
Host Species:Rabbit
Immunogen:Recombinant fusion protein containing a sequence corresponding to amino acids 371-540 of human DDX28 (NP_060850.2).
Application:WB
Recommended Dilution:WB 1:500 - 1:2000
Reactivity:Human, Mouse, Rat
Positive Samples:Rat lung
Immunogen:Recombinant fusion protein containing a sequence corresponding to amino acids 371-540 of human DDX28 (NP_060850.2).
Purification Method:Affinity purification
Storage Buffer:Store at -20°C. Avoid freeze / thaw cycles. Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3.
Isotype:IgG
Sequence:RLKG ADKV AELV HILK HRDR AERT GPSG TVLV FCNS SSTV NWLG YILD DHKI QHLR LQGQ MPAL MRVG IFQS FQKS SRDI LLCT DIAS RGLD STGV ELVV NYDF PPTL QDYI HRAG RVGR VGSE VPGT VISF VTHP WDVS LVQK IELA ARRR RSLP GLAS SVKE PLPQ AT
Gene ID:55794
Uniprot:Q9NUL7
Cellular Location:
Calculated MW:59kDa
Observed MW:60kDa
Anti-DDX28 Antibody (CAB17728)Western blot - DDX28 Polyclonal Antibody (CAB17728)
Synonyms:DDX28, MDDX28
Background:DEAD box proteins, characterized by the conserved motif Asp-Glu-Ala-Asp (DEAD), are putative RNA helicases. They are implicated in a number of cellular processes involving alteration of RNA secondary structure, such as translation initiation, nuclear and mitochondrial splicing, and ribosome and spliceosome assembly. Based on their distribution patterns, some members of the DEAD box protein family are believed to be involved in embryogenesis, spermatogenesis, and cellular growth and division. This gene is intronless. It encodes an RNA-dependent ATPase. The encoded protein is localized in the mitochondria and the nucleus, and can be transported between the mitochondria and the nucleus. [provided by RefSeq, Jul 2008]
UniProt Protein Function:DDX28: May be involved in RNA processing or transport. Has RNA and Mg(2+)-dependent ATPase activity. Belongs to the DEAD box helicase family.
UniProt Protein Details:

Protein type:EC 3.6.4.13; Hydrolase; RNA-binding

Chromosomal Location of Human Ortholog: 16q22.1

Cellular Component: cytoplasm; mitochondrion; nucleolus; nucleus

Molecular Function:ATP-dependent RNA helicase activity; rRNA binding

Biological Process: RNA secondary structure unwinding

NCBI Summary:DEAD box proteins, characterized by the conserved motif Asp-Glu-Ala-Asp (DEAD), are putative RNA helicases. They are implicated in a number of cellular processes involving alteration of RNA secondary structure, such as translation initiation, nuclear and mitochondrial splicing, and ribosome and spliceosome assembly. Based on their distribution patterns, some members of the DEAD box protein family are believed to be involved in embryogenesis, spermatogenesis, and cellular growth and division. This gene is intronless. It encodes an RNA-dependent ATPase. The encoded protein is localized in the mitochondria and the nucleus, and can be transported between the mitochondria and the nucleus. [provided by RefSeq, Jul 2008]
UniProt Code:Q9NUL7
NCBI GenInfo Identifier:296434476
NCBI Gene ID:55794
NCBI Accession:Q9NUL7.2
UniProt Related Accession:Q9NUL7
Molecular Weight:59,581 Da
NCBI Full Name:Probable ATP-dependent RNA helicase DDX28
NCBI Synonym Full Names:DEAD-box helicase 28
NCBI Official Symbol:DDX28  
NCBI Official Synonym Symbols:MDDX28  
NCBI Protein Information:probable ATP-dependent RNA helicase DDX28
UniProt Protein Name:Probable ATP-dependent RNA helicase DDX28
UniProt Synonym Protein Names:Mitochondrial DEAD box protein 28
Protein Family:Probable ATP-dependent RNA helicase
UniProt Gene Name:DDX28  
UniProt Entry Name:DDX28_HUMAN
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