Cell Biology Antibodies 5

Anti-DDX27 Antibody (CAB14911)

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SKU:
CAB14911
Product Type:
Antibody
Reactivity:
Mouse
Reactivity:
Rat
Host Species:
Rabbit
Isotype:
IgG
Antibody Type:
Polyclonal Antibody
Research Area:
Cell Biology

Description

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Antibody Name:Anti-DDX27 Antibody
Antibody SKU:CAB14911
Antibody Size:20uL, 50uL, 100uL
Application:IHC
Reactivity:Mouse, Rat
Host Species:Rabbit
Immunogen:Recombinant fusion protein containing a sequence corresponding to amino acids 587-796 of human DDX27 (NP_060365.7).
Application:IHC
Recommended Dilution:IHC 1:50 - 1:200
Reactivity:Mouse, Rat
Positive Samples:
Immunogen:Recombinant fusion protein containing a sequence corresponding to amino acids 587-796 of human DDX27 (NP_060365.7).
Purification Method:Affinity purification
Storage Buffer:Store at -20'C. Avoid freeze / thaw cycles. Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3.
Isotype:IgG
Sequence:KARI LPQD VILK FRDK IEKM EKDV YAVL QLEA EEKE MQQS EAQI NTAK RLLE KGKE AVVQ EPER SWFQ TKEE RKKE KIAK ALQE FDLA LRGK KKRK KFMK DAKK KGEM TAEE RSQF EILK AQMF AERL AKRN RRAK RARA MPEE EPVR GPAK KQKQ GKKS VFDE ELTN TSKK ALKQ YRAG PSFE ERKQ LGLP HQRR GGNF KSKS RYKR RK
Gene ID:55661
Uniprot:Q96GQ7
Cellular Location:Nucleus
Calculated MW:89kDa
Observed MW:
Synonyms:DDX27, DRS1, Drs1p, HSPC259, PP3241, RHLP, dJ686N3.1
Background:DEAD box proteins, characterized by the conserved motif Asp-Glu-Ala-Asp (DEAD), are putative RNA helicases. They are implicated in a number of cellular processes involving alteration of RNA secondary structure such as translation initiation, nuclear and mitochondrial splicing, and ribosome and spliceosome assembly. Based on their distribution patterns, some members of this family are believed to be involved in embryogenesis, spermatogenesis, and cellular growth and division. This gene encodes a DEAD box protein involved in the processing of 5.8S and 28S ribosomal RNAs. More specifically, the encoded protein localizes to the nucleolus, where it interacts with the PeBoW complex to ensure proper 3' end formation of 47S rRNA.
UniProt Protein Function:DDX27: Probable ATP-dependent RNA helicase. Belongs to the DEAD box helicase family. DDX27/DRS1 subfamily.
UniProt Protein Details:

Protein type:RNA-binding; Helicase; EC 3.6.4.13

Chromosomal Location of Human Ortholog: 20q13.13

Cellular Component: nucleolus

Molecular Function:ATP-dependent RNA helicase activity; protein binding

Biological Process: RNA secondary structure unwinding; rRNA processing

NCBI Summary:DEAD box proteins, characterized by the conserved motif Asp-Glu-Ala-Asp (DEAD), are putative RNA helicases. They are implicated in a number of cellular processes involving alteration of RNA secondary structure such as translation initiation, nuclear and mitochondrial splicing, and ribosome and spliceosome assembly. Based on their distribution patterns, some members of this family are believed to be involved in embryogenesis, spermatogenesis, and cellular growth and division. This gene encodes a DEAD box protein, the function of which has not been determined. [provided by RefSeq, Jul 2008]
UniProt Code:Q96GQ7
NCBI GenInfo Identifier:29427946
NCBI Gene ID:55661
NCBI Accession:Q96GQ7.2
UniProt Secondary Accession:Q96GQ7,Q5VXM7, Q8WYG4, Q969N7, Q96F57, Q96L97, Q9BWY9 Q9BXF0, Q9H990, Q9NWU3, A0AVB6, B7ZLY1,
UniProt Related Accession:Q96GQ7
Molecular Weight:89,835 Da
NCBI Full Name:Probable ATP-dependent RNA helicase DDX27
NCBI Synonym Full Names:DEAD-box helicase 27
NCBI Official Symbol:DDX27  
NCBI Official Synonym Symbols:DRS1; RHLP; Drs1p; PP3241; HSPC259; dJ686N3.1  
NCBI Protein Information:probable ATP-dependent RNA helicase DDX27
UniProt Protein Name:Probable ATP-dependent RNA helicase DDX27
UniProt Synonym Protein Names:DEAD box protein 27
Protein Family:Probable ATP-dependent RNA helicase
UniProt Gene Name:DDX27  
UniProt Entry Name:DDX27_HUMAN
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