Cell Biology Antibodies 18
Anti-DDHD2 Antibody (CAB18434)
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- SKU:
- CAB18434
- Product Type:
- Antibody
- Reactivity:
- Human
- Reactivity:
- Mouse
- Host Species:
- Rabbit
- Isotype:
- IgG
- Research Area:
- Cell Biology
Description
| Antibody Name: | Anti-DDHD2 Antibody |
| Antibody SKU: | CAB18434 |
| Antibody Size: | 20uL, 50uL, 100uL |
| Application: | WB |
| Reactivity: | Human, Mouse |
| Host Species: | Rabbit |
| Immunogen: | Recombinant protein of human DDHD2. |
| Application: | WB |
| Recommended Dilution: | WB 1:500 - 1:2000 |
| Reactivity: | Human, Mouse |
| Positive Samples: |
| Immunogen: | Recombinant protein of human DDHD2. |
| Purification Method: | Affinity purification |
| Storage Buffer: | Store at -20°C. Avoid freeze / thaw cycles. Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3. |
| Isotype: | IgG |
| Sequence: | Email for sequence |
| Gene ID: | 23259 |
| Uniprot: | O94830 |
| Cellular Location: | |
| Calculated MW: | |
| Observed MW: | Refer to figures |
| Synonyms: | SAMWD1, SPG54, iPLA(1)gamma, DDHD2 |
| Background: |
| UniProt Protein Function: | DDHD2: Phospholipase that hydrolyzes preferentially phosphatidic acid and phosphatidylethanolamine. May be involved in the maintenance of the endoplasmic reticulum and/or Golgi structures. Belongs to the PA-PLA1 family. |
| UniProt Protein Details: | Protein type:EC 3.1.1.-; Hydrolase Chromosomal Location of Human Ortholog: 8p11.23 Cellular Component: cytoplasm; cytosol; ER-Golgi intermediate compartment; Golgi apparatus; microtubule organizing center Molecular Function:hydrolase activity; metal ion binding Biological Process: glycerophospholipid biosynthetic process; lipid catabolic process; phosphatidic acid biosynthetic process; phospholipid metabolic process Disease: Spastic Paraplegia 54, Autosomal Recessive |
| NCBI Summary: | This gene encodes a phospholipase enzyme containing sterile-alpha-motif (SAM), WWE, and DDHD domains. This protein participates in membrane trafficking between the endoplastic reticulum and the Golgi body. Mutations in this gene can cause autosomal recessive spastic paraplegia 54. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Dec 2013] |
| UniProt Code: | O94830 |
| NCBI GenInfo Identifier: | 256017247 |
| NCBI Gene ID: | 23259 |
| NCBI Accession: | NP_001157704.1 |
| UniProt Secondary Accession: | O94830,Q9H8X7, B3KWV2, B3KXB5, |
| UniProt Related Accession: | O94830 |
| Molecular Weight: | 37,682 Da |
| NCBI Full Name: | phospholipase DDHD2 isoform 1 |
| NCBI Synonym Full Names: | DDHD domain containing 2 |
| NCBI Official Symbol: | DDHD2 |
| NCBI Official Synonym Symbols: | SPG54; SAMWD1; iPLA(1)gamma |
| NCBI Protein Information: | phospholipase DDHD2 |
| UniProt Protein Name: | Phospholipase DDHD2 |
| UniProt Synonym Protein Names: | DDHD domain-containing protein 2; KIAA0725p; SAM, WWE and DDHD domain-containing protein 1 |
| Protein Family: | Phospholipase |
| UniProt Gene Name: | DDHD2 |
| UniProt Entry Name: | DDHD2_HUMAN |
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