Cell Biology Antibodies 6

Anti-DCTN5 Antibody (CAB15915)

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SKU:
CAB15915
Product Type:
Antibody
Reactivity:
Human
Reactivity:
Mouse
Reactivity:
Rat
Host Species:
Rabbit
Isotype:
IgG
Antibody Type:
Polyclonal Antibody
Research Area:
Cell Biology

Description

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Antibody Name:Anti-DCTN5 Antibody
Antibody SKU:CAB15915
Antibody Size:20uL, 50uL, 100uL
Application:WB
Reactivity:Human, Mouse, Rat
Host Species:Rabbit
Immunogen:A synthetic peptide corresponding to a sequence within amino acids 1-100 of human DCTN5 (NP_115875.1).
Application:WB
Recommended Dilution:WB 1:500 - 1:2000
Reactivity:Human, Mouse, Rat
Positive Samples:MCF7, 293T, Mouse eye, Mouse testis, Mouse kidney, Rat lung, Rat spleen
Immunogen:A synthetic peptide corresponding to a sequence within amino acids 1-100 of human DCTN5 (NP_115875.1).
Purification Method:Affinity purification
Storage Buffer:Store at -20'C. Avoid freeze / thaw cycles. Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3.
Isotype:IgG
Sequence:MELG ELLY NKSE YIET ASGN KVSR QSVL CGSQ NIVL NGKT IVMN DCII RGDL ANVR VGRH CVVK SRSV IRPP FKKF SKGV AFFP LHIG DHVF IEED CVVN
Gene ID:84516
Uniprot:Q9BTE1
Cellular Location:Chromosome, Cytoplasm, centromere, cytoskeleton, kinetochore
Calculated MW:9kDa/16kDa/20kDa
Observed MW:20kDa
Synonyms:DCTN5
Background:This gene encodes a subunit of dynactin, a component of the cytoplasmic dynein motor machinery involved in minus-end-directed transport. The encoded protein is a component of the pointed-end subcomplex and is thought to bind membranous cargo. A pseudogene of this gene is located on the long arm of chromosome 1. Alternatively spliced transcript variants encoding multiple isoforms have been observed for this gene.
UniProt Protein Function:dynactin 5: a subunit of dynactin, a component of the cytoplasmic dynein motor machinery involved in minus-end-directed transport. The encoded protein is a component of the pointed-end subcomplex and is thought to bind membranous cargo. A pseudogene of this gene is located on the long arm of chromosome 1. Alternatively spliced transcript variants encoding multiple isoforms have been observed for this gene. [provided by RefSeq, Jan 2011]
UniProt Protein Details:

Protein type:Cytoskeletal

Chromosomal Location of Human Ortholog: 16p12.2

Cellular Component: centrosome; cytosol

Biological Process: antigen processing and presentation of exogenous peptide antigen via MHC class II

NCBI Summary:This gene encodes a subunit of dynactin, a component of the cytoplasmic dynein motor machinery involved in minus-end-directed transport. The encoded protein is a component of the pointed-end subcomplex and is thought to bind membranous cargo. A pseudogene of this gene is located on the long arm of chromosome 1. Alternatively spliced transcript variants encoding multiple isoforms have been observed for this gene. [provided by RefSeq, Jan 2011]
UniProt Code:Q9BTE1
NCBI GenInfo Identifier:62900103
NCBI Gene ID:84516
NCBI Accession:Q9BTE1.1
UniProt Secondary Accession:Q9BTE1,A8K9X8, H3BN51, H3BQA4,
UniProt Related Accession:Q9BTE1
Molecular Weight:9,740 Da
NCBI Full Name:Dynactin subunit 5
NCBI Synonym Full Names:dynactin 5 (p25)
NCBI Official Symbol:DCTN5  
NCBI Protein Information:dynactin subunit 5; dynactin 4; dynactin subunit p25
UniProt Protein Name:Dynactin subunit 5
UniProt Synonym Protein Names:Dynactin subunit p25
UniProt Gene Name:DCTN5  
UniProt Entry Name:DCTN5_HUMAN
Anti-DCTN5 Antibody (CAB15915)Western blot analysis of extracts of various cell lines, using DCTN5 antibody (CAB15915) at 1:1000 dilution. Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) (CABS014) at 1:10000 dilution. Lysates/proteins: 25ug per lane. Blocking buffer: 3% nonfat dry milk in TBST. Detection: ECL Basic Kit (RM00020). Exposure time: 60s.
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