Description
| Product Name: | DCP1B Rabbit pAb |
| Product Code: | CAB20150 |
| Size: | 50uL, 100uL |
| Synonyms: | DCP1 |
| Applications: | WB |
| Reactivity: | Human, Rat |
| Host Species: | Rabbit |
| Immunogen: | Recombinant protein of human DCP1B. |
| Applications: | WB |
| Recommended Dilutions: | WB 1:1000 - 1:2000 |
| Reactivity: | Human, Rat |
| Positive Samples: | Jurkat, Rat testis |
| Immunogen: | Recombinant protein of human DCP1B. |
| Purification Method: | Affinity purification |
| Storage: | Store at -20°C. Avoid freeze / thaw cycles. Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3. |
| Isotype: | IgG |
| Sequence: | Email for sequence |
| Gene ID: | 196513 |
| Uniprot: | Q8IZD4 |
| Calculated MW: | 68kDa |
| Observed MW: | 75KDa |
| UniProt Protein Function: | DCP1B: an mRNA decapping enzyme. Plays a role in regulating the mRNA degradation pathway.Protein type: RNA-binding; EC 3.-.-.-; HydrolaseChromosomal Location of Human Ortholog: 12p13.33Cellular Component: intracellular membrane-bound organelle; membrane; cytoplasm; nucleus; cytosolMolecular Function: mRNA binding; protein binding; hydrolase activity; RNA 7-methylguanosine cap binding; enzyme regulator activityBiological Process: deadenylation-dependent decapping; regulation of catalytic activity; deadenylation-independent decapping; mRNA catabolic process, nonsense-mediated decay; gene expression; mRNA catabolic process, deadenylation-dependent decay |
| UniProt Protein Details: | |
| NCBI Summary: | DCP1B is a core component of the mRNA decapping complex, a key factor in the regulation of mRNA decay (Lykke-Andersen, 2002 [PubMed 12417715]).[supplied by OMIM, Mar 2008] |
| UniProt Code: | Q8IZD4 |
| NCBI GenInfo Identifier: | 317373353 |
| NCBI Gene ID: | 196513 |
| NCBI Accession: | Q8IZD4.2 |
| UniProt Secondary Accession: | Q8IZD4,Q86XH9, Q96BP8, Q96MZ8, B4DRD1 |
| UniProt Related Accession: | Q8IZD4 |
| Molecular Weight: | 617 |
| NCBI Full Name: | mRNA-decapping enzyme 1B |
| NCBI Synonym Full Names: | decapping mRNA 1B |
| NCBI Official Symbol: | DCP1B |
| NCBI Official Synonym Symbols: | DCP1; hDcp1b |
| NCBI Protein Information: | mRNA-decapping enzyme 1B; decapping enzyme hDcp1b; DCP1 decapping enzyme homolog B |
| UniProt Protein Name: | mRNA-decapping enzyme 1B |
| UniProt Synonym Protein Names: | |
| Protein Family: | mRNA-decapping enzyme |
| UniProt Gene Name: | DCP1B |
| UniProt Entry Name: | DCP1B_HUMAN |