Cell Biology Antibodies 5

Anti-DBP Antibody (CAB15270)

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SKU:
CAB15270
Product Type:
Antibody
Reactivity:
Human
Host Species:
Rabbit
Isotype:
IgG
Antibody Type:
Polyclonal Antibody
Research Area:
Cell Biology

Description

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Antibody Name:Anti-DBP Antibody
Antibody SKU:CAB15270
Antibody Size:20uL, 50uL, 100uL
Application:WB
Reactivity:Human
Host Species:Rabbit
Immunogen:Recombinant fusion protein containing a sequence corresponding to amino acids 1-325 of human DBP (NP_001343.2).
Application:WB
Recommended Dilution:WB 1:200 - 1:2000
Reactivity:Human
Positive Samples:LO2, HeLa
Immunogen:Recombinant fusion protein containing a sequence corresponding to amino acids 1-325 of human DBP (NP_001343.2).
Purification Method:Affinity purification
Storage Buffer:Store at -20'C. Avoid freeze / thaw cycles. Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3.
Isotype:IgG
Sequence:MARP VSDR TPAP LLLG GPAG TPPG GGAL LGLR SLLQ GTSK PKEP ASCL LKEK ERKA ALPA ATTP GPGL ETAG PADA PAGA VVGG GSPR GRPG PVPA PGLL APLL WERT LPFG DVEY VDLD AFLL EHGL PPSP PPPG GPSP EPSP ARTP APSP GPGS CGSA SPRS SPGH APAR AALG TASG HRAG LTSR DTPS PVDP DTVE VLMT FEPD PADL ALSS IPGH ETFD PRRH RFSE EELK PQPI MKKA RKIQ VPEE QKDE KYWS RRYK NNEA AKRS RDAR RLKE NQIS VRAA FLEK ENAL LRQE VVAV RQEL SHYR AVLS RYQA QHGA L
Gene ID:1628
Uniprot:Q10586
Cellular Location:Nucleus
Calculated MW:34kDa
Observed MW:36kDa
Synonyms:DBP, DABP
Background:The protein encoded by this gene is a member of the PAR bZIP transcription factor family and binds to specific sequences in the promoters of several genes, such as albumin, CYP2A4, and CYP2A5. The encoded protein can bind DNA as a homo- or heterodimer and is involved in the regulation of some circadian rhythm genes.
UniProt Protein Function:DBP: This transcriptional activator recognizes and binds to the sequence 5'-RTTAYGTAAY-3' found in the promoter of genes such as albumin, CYP2A4 and CYP2A5. It is not essential for circadian rhythm generation, but modulates important clock output genes. May be a direct target for regulation by the circadian pacemaker component clock. May affect circadian period and sleep regulation. Belongs to the bZIP family. PAR subfamily.
UniProt Protein Details:

Protein type:Transcription factor; DNA-binding

Chromosomal Location of Human Ortholog: 19q13.3

Biological Process: positive regulation of transcription from RNA polymerase II promoter; regulation of transcription from RNA polymerase II promoter

NCBI Summary:The protein encoded by this gene is a member of the PAR bZIP transcription factor family and binds to specific sequences in the promoters of several genes, such as albumin, CYP2A4, and CYP2A5. The encoded protein can bind DNA as a homo- or heterodimer and is involved in the regulation of some circadian rhythm genes. [provided by RefSeq, Jul 2014]
UniProt Code:Q10586
NCBI GenInfo Identifier:1706312
NCBI Gene ID:1628
NCBI Accession:Q10586.1
UniProt Secondary Accession:Q10586,A2I2P4,
UniProt Related Accession:Q10586
Molecular Weight:34,349 Da
NCBI Full Name:D site-binding protein
NCBI Synonym Full Names:D-box binding PAR bZIP transcription factor
NCBI Official Symbol:DBP  
NCBI Official Synonym Symbols:DABP  
NCBI Protein Information:D site-binding protein
UniProt Protein Name:D site-binding protein
UniProt Synonym Protein Names:Albumin D box-binding protein; Albumin D-element-binding protein; Tax-responsive enhancer element-binding protein 302; TaxREB302
Protein Family:D site-binding protein
UniProt Gene Name:DBP  
UniProt Entry Name:DBP_HUMAN
Anti-DBP Antibody (CAB15270)Western blot analysis of extracts of various cell lines, using DBP antibody (CAB15270) at 1:1000 dilution. Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) (CABS014) at 1:10000 dilution. Lysates/proteins: 25ug per lane. Blocking buffer: 3% nonfat dry milk in TBST. Detection: ECL Basic Kit (RM00020). Exposure time: 15S.
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