Cell Biology Antibodies 1

Anti-Cytokeratin 9 Antibody (CAB10119)

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SKU:
CAB10119
Product Type:
Antibody
Reactivity:
Human
Reactivity:
Mouse
Reactivity:
Rat
Host Species:
Rabbit
Isotype:
IgG
Antibody Type:
Polyclonal Antibody
Research Area:
Cell Biology

Description

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Antibody Name:Anti-Cytokeratin 9 Antibody
Antibody SKU:CAB10119
Antibody Size:20uL, 50uL, 100uL
Application:WB
Reactivity:Human, Mouse, Rat
Host Species:Rabbit
Immunogen:Recombinant fusion protein containing a sequence corresponding to amino acids 150-450 of human Cytokeratin 9 (NP_000217.2).
Application:WB
Recommended Dilution:WB 1:1000 - 1:4000
Reactivity:Human, Mouse, Rat
Positive Samples:HeLa, LO2, U-251MG, Mouse liver, Mouse testis, Rat testis
Immunogen:Recombinant fusion protein containing a sequence corresponding to amino acids 150-450 of human Cytokeratin 9 (NP_000217.2).
Purification Method:Affinity purification
Storage Buffer:Store at -20'C. Avoid freeze / thaw cycles. Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3.
Isotype:IgG
Sequence:TANE KSTM QELN SRLA SYLD KVQA LEEA NNDL ENKI QDWY DKKG PAAI QKNY SPYY NTID DLKD QIVD LTVG NNKT LLDI DNTR MTLD DFRI KFEM EQNL RQGV DADI NGLR QVLD NLTM EKSD LEMQ YETL QEEL MALK KNHK EEMS QLTG QNSG DVNV EINV APGK DLTK TLND MRQE YEQL IAKN RKDI ENQY ETQI TQIE HEVS SSGQ EVQS SAKE VTQL RHGV QELE IELQ SQLS KKAA LEKS LEDT KNRY CGQL QMIQ EQIS NLEA QITD VRQE IECQ NQEY SLLL SIKM RLEK E
Gene ID:3857
Uniprot:P35527
Cellular Location:
Calculated MW:62kDa
Observed MW:62kDa
Synonyms:KRT9, CK-9, EPPK, K9, keratin 9
Background:This gene encodes the type I keratin 9, an intermediate filament chain expressed only in the terminally differentiated epidermis of palms and soles. Mutations in this gene cause epidermolytic palmoplantar keratoderma.
UniProt Protein Function:K9: a type I cytoskeletal keratin. The keratins are intermediate filament proteins responsible for the structural integrity of epithelial cells and are subdivided into cytokeratins and hair keratins. There are two types of cytoskeletal and microfibrillar keratin: type I (acidic; 40-55 kDa) [K9 to K20] and type II (neutral to basic; 56-70 kDa) [K1 to K8]. Both a basic and an acidic keratin are required for filament assembly.
UniProt Protein Details:

Protein type:Cytoskeletal

Chromosomal Location of Human Ortholog: 17q21.2

Cellular Component: extracellular space; membrane; nucleus

Molecular Function:structural constituent of cytoskeleton

Biological Process: epidermis development; intermediate filament organization; skin development

Disease: Palmoplantar Keratoderma, Epidermolytic

NCBI Summary:This gene encodes the type I keratin 9, an intermediate filament chain expressed only in the terminally differentiated epidermis of palms and soles. Mutations in this gene cause epidermolytic palmoplantar keratoderma. [provided by RefSeq, Jul 2008]
UniProt Code:P35527
NCBI GenInfo Identifier:239938886
NCBI Gene ID:3857
NCBI Accession:P35527.3
UniProt Secondary Accession:P35527,O00109, Q0IJ47, Q14665,
UniProt Related Accession:P35527
Molecular Weight:62,064 Da
NCBI Full Name:Keratin, type I cytoskeletal 9
NCBI Synonym Full Names:keratin 9
NCBI Official Symbol:KRT9  
NCBI Official Synonym Symbols:K9; CK-9; EPPK  
NCBI Protein Information:keratin, type I cytoskeletal 9
UniProt Protein Name:Keratin, type I cytoskeletal 9
UniProt Synonym Protein Names:Cytokeratin-9; CK-9; Keratin-9; K9
Protein Family:Keratin
UniProt Gene Name:KRT9  
UniProt Entry Name:K1C9_HUMAN
Anti-Cytokeratin 9 Antibody (CAB10119)Western blot analysis of extracts of various cell lines, using Cytokeratin 9 antibody (CAB10119) at 1:1000 dilution. Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) (CABS014) at 1:10000 dilution. Lysates/proteins: 25ug per lane. Blocking buffer: 3% nonfat dry milk in TBST. Detection: ECL Basic Kit (RM00020). Exposure time: 5s.
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