Cell Biology Antibodies 7

Anti-CYSLTR2 Antibody (CAB16556)

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SKU:
CAB16556
Product Type:
Antibody
Reactivity:
Mouse
Host Species:
Rabbit
Isotype:
IgG
Antibody Type:
Polyclonal Antibody
Research Area:
Cell Biology

Description

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Antibody Name:Anti-CYSLTR2 Antibody
Antibody SKU:CAB16556
Antibody Size:20uL, 50uL, 100uL
Application:WB
Reactivity:Mouse
Host Species:Rabbit
Immunogen:A synthetic peptide corresponding to a sequence within amino acids 200 to the C-terminus of human CYSLTR2 (NP_001295394.1).
Application:WB
Recommended Dilution:WB 1:500 - 1:2000
Reactivity:Mouse
Positive Samples:mouse kidney
Immunogen:A synthetic peptide corresponding to a sequence within amino acids 200 to the C-terminus of human CYSLTR2 (NP_001295394.1).
Purification Method:Affinity purification
Storage Buffer:Store at -20'C. Avoid freeze / thaw cycles. Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3.
Isotype:IgG
Sequence:TMNY IALV VGCL LPFF TLSI CYLL IIRV LLKV EVPE SGLR VSHR KALT TIII TLII FFLC FLPY HTLR TVHL TTWK VGLC KDRL HKAL VITL ALAA ANAC FNPL LYYF AGEN FKDR LKSA LRKG HPQK AKTK CVFP VSVW LRKE TRV
Gene ID:57105
Uniprot:Q9NS75
Cellular Location:Cell membrane, Multi-pass membrane protein
Calculated MW:39kDa
Observed MW:40kDa
Synonyms:CYSLTR2, CYSLT2, CYSLT2R, GPCR21, HG57, HPN321, KPG_011, PSEC0146, hGPCR21
Background:The cysteinyl leukotrienes LTC4, LTD4, and LTE4 are important mediators of human bronchial asthma. Pharmacologic studies have determined that cysteinyl leukotrienes activate at least 2 receptors, the protein encoded by this gene and CYSLTR1. This encoded receptor is a member of the superfamily of G protein-coupled receptors. It seems to play a major role in endocrine and cardiovascular systems.
UniProt Protein Function:Receptor for cysteinyl leukotrienes. The response is mediated via a G-protein that activates a phosphatidylinositol-calcium second messenger system. Stimulation by BAY u9773, a partial agonist, induces specific contractions of pulmonary veins and might also have an indirect role in the relaxation of the pulmonary vascular endothelium. The rank order of affinities for the leukotrienes is LTC4 = LTD4 >> LTE4.
NCBI Summary:The cysteinyl leukotrienes LTC4, LTD4, and LTE4 are important mediators of human bronchial asthma. Pharmacologic studies have determined that cysteinyl leukotrienes activate at least 2 receptors, the protein encoded by this gene and CYSLTR1. This encoded receptor is a member of the superfamily of G protein-coupled receptors. It seems to play a major role in endocrine and cardiovascular systems. [provided by RefSeq, Jul 2008]
UniProt Code:Q9NS75
NCBI GenInfo Identifier:818213437
NCBI Gene ID:57105
NCBI Accession:NP_001295394.1
UniProt Secondary Accession:Q9NS75,Q9HCQ2,
UniProt Related Accession:Q9NS75
Molecular Weight:35 KD
NCBI Full Name:cysteinyl leukotriene receptor 2
NCBI Synonym Full Names:cysteinyl leukotriene receptor 2
NCBI Official Symbol:CYSLTR2  
NCBI Official Synonym Symbols:HG57; CYSLT2; GPCR21; HPN321; CYSLT2R; KPG_011; hGPCR21; PSEC0146  
NCBI Protein Information:cysteinyl leukotriene receptor 2
UniProt Protein Name:Cysteinyl leukotriene receptor 2
UniProt Synonym Protein Names:G-protein coupled receptor GPCR21; hGPCR21; G-protein coupled receptor HG57; HPN321
UniProt Gene Name:CYSLTR2  
Anti-CYSLTR2 Antibody (CAB16556)Western blot analysis of extracts of mouse kidney, using CYSLTR2 antibody (CAB16556) at 1:1000 dilution. Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) (CABS014) at 1:10000 dilution. Lysates/proteins: 25ug per lane. Blocking buffer: 3% nonfat dry milk in TBST. Detection: ECL Basic Kit (RM00020). Exposure time: 10s.
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