Signal Transduction Antibodies 3

Anti-CYGB Antibody (CAB6488)

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SKU:
CAB6488
Product Type:
Antibody
Reactivity:
Mouse
Host Species:
Rabbit
Isotype:
IgG
Antibody Type:
Polyclonal Antibody
Research Area:
Signal Transduction

Description

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Antibody Name:Anti-CYGB Antibody
Antibody SKU:CAB6488
Antibody Size:20uL, 50uL, 100uL
Application:WB IF
Reactivity:Mouse
Host Species:Rabbit
Immunogen:Recombinant fusion protein containing a sequence corresponding to amino acids 1-190 of human CYGB (NP_599030.1).
Application:WB IF
Recommended Dilution:WB 1:500 - 1:2000 IF 1:50 - 1:100
Reactivity:Mouse
Positive Samples:Mouse brain, Mouse lung
Immunogen:Recombinant fusion protein containing a sequence corresponding to amino acids 1-190 of human CYGB (NP_599030.1).
Purification Method:Affinity purification
Storage Buffer:Store at -20'C. Avoid freeze / thaw cycles. Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3.
Isotype:IgG
Sequence:MEKV PGEM EIER RERS EELS EAER KAVQ AMWA RLYA NCED VGVA ILVR FFVN FPSA KQYF SQFK HMED PLEM ERSP QLRK HACR VMGA LNTV VENL HDPD KVSS VLAL VGKA HALK HKVE PVYF KILS GVIL EVVA EEFA SDFP PETQ RAWA KLRG LIYS HVTA AYKE VGWV QQVP NATT PPAT LPSS GP
Gene ID:114757
Uniprot:Q8WWM9
Cellular Location:Cytoplasm
Calculated MW:21kDa
Observed MW:21kDa
Synonyms:CYGB, HGB, STAP
Background:This gene encodes a globin protein found in vertebrate cells. The encoded protein is described as a hexacoordinate hemoglobin which binds ligand differently from the pentacoordinate hemoglobins involved in oxygen transport, and may be involved in protection during oxidative stress. This gene is located on chromosome 17 in the same region as a retinal gene which is mutated in progressive rod-cone degeneration, but in the opposite orientation.
UniProt Protein Function:CYGB: May have a protective function during conditions of oxidative stress. May be involved in intracellular oxygen storage or transfer. Belongs to the globin family.
UniProt Protein Details:

Chromosomal Location of Human Ortholog: 17q25

Cellular Component: cytosol

Molecular Function:nitric oxide dioxygenase activity; peroxidase activity; protein binding

Biological Process: regulation of nitric-oxide synthase activity; response to oxidative stress

NCBI Summary:This gene encodes a globin protein found in vertebrate cells. The encoded protein is described as a hexacoordinate hemoglobin which binds ligand differently from the pentacoordinate hemoglobins involved in oxygen transport, and may be involved in protection during oxidative stress. This gene is located on chromosome 17 in the same region as a retinal gene which is mutated in progressive rod-cone degeneration, but in the opposite orientation. [provided by RefSeq, Jan 2012]
UniProt Code:Q8WWM9
NCBI GenInfo Identifier:21263504
NCBI Gene ID:114757
NCBI Accession:Q8WWM9.1
UniProt Secondary Accession:Q8WWM9,Q541Y7, Q8N2X5,
UniProt Related Accession:Q8WWM9
Molecular Weight:21,405 Da
NCBI Full Name:Cytoglobin
NCBI Synonym Full Names:cytoglobin
NCBI Official Symbol:CYGB  
NCBI Official Synonym Symbols:HGB; STAP  
NCBI Protein Information:cytoglobin
UniProt Protein Name:Cytoglobin
UniProt Synonym Protein Names:Histoglobin; HGb; Stellate cell activation-associated protein
Protein Family:Cytoglobin
UniProt Gene Name:CYGB  
UniProt Entry Name:CYGB_HUMAN
Anti-CYGB Antibody (CAB6488)Western blot analysis of extracts of various cell lines, using CYGB antibody (CAB6488) at 1:1000 dilution. Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) (CABS014) at 1:10000 dilution. Lysates/proteins: 25ug per lane. Blocking buffer: 3% nonfat dry milk in TBST. Detection: ECL Enhanced Kit (RM00021). Exposure time: 90s.
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