Signal Transduction Antibodies 3
Anti-CYGB Antibody (CAB6488)
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- SKU:
- CAB6488
- Product Type:
- Antibody
- Reactivity:
- Mouse
- Host Species:
- Rabbit
- Isotype:
- IgG
- Antibody Type:
- Polyclonal Antibody
- Research Area:
- Signal Transduction
Description
| Antibody Name: | Anti-CYGB Antibody |
| Antibody SKU: | CAB6488 |
| Antibody Size: | 20uL, 50uL, 100uL |
| Application: | WB IF |
| Reactivity: | Mouse |
| Host Species: | Rabbit |
| Immunogen: | Recombinant fusion protein containing a sequence corresponding to amino acids 1-190 of human CYGB (NP_599030.1). |
| Application: | WB IF |
| Recommended Dilution: | WB 1:500 - 1:2000 IF 1:50 - 1:100 |
| Reactivity: | Mouse |
| Positive Samples: | Mouse brain, Mouse lung |
| Immunogen: | Recombinant fusion protein containing a sequence corresponding to amino acids 1-190 of human CYGB (NP_599030.1). |
| Purification Method: | Affinity purification |
| Storage Buffer: | Store at -20'C. Avoid freeze / thaw cycles. Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3. |
| Isotype: | IgG |
| Sequence: | MEKV PGEM EIER RERS EELS EAER KAVQ AMWA RLYA NCED VGVA ILVR FFVN FPSA KQYF SQFK HMED PLEM ERSP QLRK HACR VMGA LNTV VENL HDPD KVSS VLAL VGKA HALK HKVE PVYF KILS GVIL EVVA EEFA SDFP PETQ RAWA KLRG LIYS HVTA AYKE VGWV QQVP NATT PPAT LPSS GP |
| Gene ID: | 114757 |
| Uniprot: | Q8WWM9 |
| Cellular Location: | Cytoplasm |
| Calculated MW: | 21kDa |
| Observed MW: | 21kDa |
| Synonyms: | CYGB, HGB, STAP |
| Background: | This gene encodes a globin protein found in vertebrate cells. The encoded protein is described as a hexacoordinate hemoglobin which binds ligand differently from the pentacoordinate hemoglobins involved in oxygen transport, and may be involved in protection during oxidative stress. This gene is located on chromosome 17 in the same region as a retinal gene which is mutated in progressive rod-cone degeneration, but in the opposite orientation. |
| UniProt Protein Function: | CYGB: May have a protective function during conditions of oxidative stress. May be involved in intracellular oxygen storage or transfer. Belongs to the globin family. |
| UniProt Protein Details: | Chromosomal Location of Human Ortholog: 17q25 Cellular Component: cytosol Molecular Function:nitric oxide dioxygenase activity; peroxidase activity; protein binding Biological Process: regulation of nitric-oxide synthase activity; response to oxidative stress |
| NCBI Summary: | This gene encodes a globin protein found in vertebrate cells. The encoded protein is described as a hexacoordinate hemoglobin which binds ligand differently from the pentacoordinate hemoglobins involved in oxygen transport, and may be involved in protection during oxidative stress. This gene is located on chromosome 17 in the same region as a retinal gene which is mutated in progressive rod-cone degeneration, but in the opposite orientation. [provided by RefSeq, Jan 2012] |
| UniProt Code: | Q8WWM9 |
| NCBI GenInfo Identifier: | 21263504 |
| NCBI Gene ID: | 114757 |
| NCBI Accession: | Q8WWM9.1 |
| UniProt Secondary Accession: | Q8WWM9,Q541Y7, Q8N2X5, |
| UniProt Related Accession: | Q8WWM9 |
| Molecular Weight: | 21,405 Da |
| NCBI Full Name: | Cytoglobin |
| NCBI Synonym Full Names: | cytoglobin |
| NCBI Official Symbol: | CYGB |
| NCBI Official Synonym Symbols: | HGB; STAP |
| NCBI Protein Information: | cytoglobin |
| UniProt Protein Name: | Cytoglobin |
| UniProt Synonym Protein Names: | Histoglobin; HGb; Stellate cell activation-associated protein |
| Protein Family: | Cytoglobin |
| UniProt Gene Name: | CYGB |
| UniProt Entry Name: | CYGB_HUMAN |
 | Western blot analysis of extracts of various cell lines, using CYGB antibody (CAB6488) at 1:1000 dilution. Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) (CABS014) at 1:10000 dilution. Lysates/proteins: 25ug per lane. Blocking buffer: 3% nonfat dry milk in TBST. Detection: ECL Enhanced Kit (RM00021). Exposure time: 90s. |
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