Cell Biology Antibodies 15
Anti-Cyclin Y Antibody (CAB17845)
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- SKU:
- CAB17845
- Product Type:
- Antibody
- Reactivity:
- Human
- Reactivity:
- Mouse
- Reactivity:
- Rat
- Host Species:
- Rabbit
- Isotype:
- IgG
- Antibody Type:
- Polyclonal Antibody
- Research Area:
- Cell Biology
Description
| Antibody Name: | Anti-Cyclin Y Antibody |
| Antibody SKU: | CAB17845 |
| Antibody Size: | 20uL, 50uL, 100uL |
| Application: | WB |
| Reactivity: | Human, Mouse, Rat |
| Host Species: | Rabbit |
| Immunogen: | Recombinant fusion protein containing a sequence corresponding to amino acids 60-120 of human CCNY (NP_859049.2). |
| Application: | WB |
| Recommended Dilution: | WB 1:500 - 1:2000 |
| Reactivity: | Human, Mouse, Rat |
| Positive Samples: | Mouse brain, C6 |
| Immunogen: | Recombinant fusion protein containing a sequence corresponding to amino acids 60-120 of human CCNY (NP_859049.2). |
| Purification Method: | Affinity purification |
| Storage Buffer: | Store at -20°C. Avoid freeze / thaw cycles. Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3. |
| Isotype: | IgG |
| Sequence: | PNLK YTIK CVAL AIYY HIKN RDPD GRML LDIF DENL HPLS KSEV PPDY DKHN PEQK QIYR F |
| Gene ID: | 219771 |
| Uniprot: | Q8ND76 |
| Cellular Location: | |
| Calculated MW: | 33kDa/36kDa/39kDa |
| Observed MW: | 39kDa |
 | Western blot - Cyclin Y Rabbit pAb (CAB17845) |
| Synonyms: | C10orf9, CBCP1, CCNX, CFP1, CCNY, cyclin-Y |
| Background: | Cyclins, such as CCNY, control cell division cycles and regulate cyclin-dependent kinases (e.g., CDC2; MIM 116940) (Li et al., 2009 [PubMed 18060517]).[supplied by OMIM, May 2009] |
| UniProt Protein Function: | CBCP1: Positive regulatory subunit of the cyclin-dependent kinase CDK14/PFTK1. Acts as a cell-cycle regulator of Wnt signaling pathway during G2/M phase by recruiting CDK14/PFTK1 to the plasma membrane and promoting phosphorylation of LRP6, leading to the activation of the Wnt signaling pathway. Isoform 3 might play a role in the activation of MYC-mediated transcription. Belongs to the cyclin family. Cyclin Y subfamily. 3 isoforms of the human protein are produced by alternative splicing. |
| UniProt Protein Details: | Protein type:Cell cycle regulation Chromosomal Location of Human Ortholog: 10p11.21 Cellular Component: plasma membrane; nucleus Molecular Function:protein binding; cyclin-dependent protein kinase regulator activity; protein kinase binding Biological Process: positive regulation of cyclin-dependent protein kinase activity; Wnt receptor signaling pathway; cell division; G2/M transition of mitotic cell cycle |
| NCBI Summary: | Cyclins, such as CCNY, control cell division cycles and regulate cyclin-dependent kinases (e.g., CDC2; MIM 116940) (Li et al., 2009 [PubMed 18060517]).[supplied by OMIM, May 2009] |
| UniProt Code: | Q8ND76 |
| NCBI GenInfo Identifier: | 544583526 |
| NCBI Gene ID: | 219771 |
| NCBI Accession: | NP_001269782.1 |
| UniProt Secondary Accession: | Q8ND76,Q2M3V4, Q2TU96, Q6NT86, Q7Z4U7, Q8TEX2, Q8TEX3 Q96M99, Q96P45, B7ZKX9, D3DRY9, |
| UniProt Related Accession: | Q8ND76 |
| Molecular Weight: | 33,245 Da |
| NCBI Full Name: | cyclin-Y isoform 2 |
| NCBI Synonym Full Names: | cyclin Y |
| NCBI Official Symbol: | CCNY |
| NCBI Official Synonym Symbols: | CCNX; CFP1; CBCP1; C10orf9 |
| NCBI Protein Information: | cyclin-Y; cyc-Y; cyclin-X; cyclin box protein 1; cyclin fold protein 1; cyclin-box carrying protein 1 |
| UniProt Protein Name: | Cyclin-Y |
| UniProt Synonym Protein Names: | Cyclin box protein 1; Cyclin fold protein 1; cyclin-X |
| UniProt Gene Name: | CCNY |
| UniProt Entry Name: | CCNY_HUMAN |
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