Cell Biology Antibodies 13
Anti-Cyclin I Antibody (CAB17623)
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- SKU:
- CAB17623
- Product Type:
- Antibody
- Reactivity:
- Human
- Reactivity:
- Mouse
- Reactivity:
- Rat
- Host Species:
- Rabbit
- Isotype:
- IgG
- Antibody Type:
- Polyclonal Antibody
- Research Area:
- Cell Biology
Description
| Antibody Name: | Anti-Cyclin I Antibody |
| Antibody SKU: | CAB17623 |
| Antibody Size: | 20uL, 50uL, 100uL |
| Application: | WB |
| Reactivity: | Human, Mouse, Rat |
| Host Species: | Rabbit |
| Immunogen: | Recombinant fusion protein containing a sequence corresponding to amino acids 257-377 of human Cyclin I (NP_006826.1). |
| Application: | WB |
| Recommended Dilution: | WB 1:500 - 1:2000 |
| Reactivity: | Human, Mouse, Rat |
| Positive Samples: | BxPC-3, Rat spleen |
| Immunogen: | Recombinant fusion protein containing a sequence corresponding to amino acids 257-377 of human Cyclin I (NP_006826.1). |
| Purification Method: | Affinity purification |
| Storage Buffer: | Store at -20°C. Avoid freeze / thaw cycles. Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3. |
| Isotype: | IgG |
| Sequence: | NSVY VYRP LKHT LVTC DKGV FRLH PSSV PGPD FSKD NSKP EVPV RGTA AFYH HLPA ASGC KQTS TKRK VEEM EVDD FYDG IKRL YNED NVSE NVGS VCGT DLSR QEGH ASPC PPLQ PVSV M |
| Gene ID: | 10983 |
| Uniprot: | Q14094 |
| Cellular Location: | |
| Calculated MW: | 40kDa/42kDa |
| Observed MW: | 43kDa |
 | Western blot - Cyclin I Rabbit pAb (CAB17623) |
| Synonyms: | CCNI, CCNI1, CYC1, CYI, cyclin-I |
| Background: | The protein encoded by this gene belongs to the highly conserved cyclin family, whose members are characterized by a dramatic periodicity in protein abundance through the cell cycle. Cyclins function as regulators of CDK kinases. Different cyclins exhibit distinct expression and degradation patterns which contribute to the temporal coordination of each mitotic event. This cyclin shows the highest similarity with cyclin G. The transcript of this gene was found to be expressed constantly during cell cycle progression. [provided by RefSeq, Jan 2017] |
| UniProt Protein Function: | CCNI: belongs to the highly conserved cyclin family, whose members are characterized by a dramatic periodicity in protein abundance through the cell cycle. Cyclins function as regulators of CDK kinases. Different cyclins exhibit distinct expression and degradation patterns which contribute to the temporal coordination of each mitotic event. This cyclin shows the highest similarity with cyclin G. The transcript of this gene was found to be expressed constantly during cell cycle progression. The function of this cyclin has not yet been determined. [provided by RefSeq, Jul 2008] |
| UniProt Protein Details: | Protein type:Cell cycle regulation Chromosomal Location of Human Ortholog: 4q21.1 Biological Process: regulation of cell cycle; spermatogenesis |
| NCBI Summary: | The protein encoded by this gene belongs to the highly conserved cyclin family, whose members are characterized by a dramatic periodicity in protein abundance through the cell cycle. Cyclins function as regulators of CDK kinases. Different cyclins exhibit distinct expression and degradation patterns which contribute to the temporal coordination of each mitotic event. This cyclin shows the highest similarity with cyclin G. The transcript of this gene was found to be expressed constantly during cell cycle progression. [provided by RefSeq, Jan 2017] |
| UniProt Code: | Q14094 |
| NCBI GenInfo Identifier: | 9296954 |
| NCBI Gene ID: | 10983 |
| NCBI Accession: | Q14094.1 |
| UniProt Related Accession: | Q14094 |
| Molecular Weight: | |
| NCBI Full Name: | Cyclin-I |
| NCBI Synonym Full Names: | cyclin I |
| NCBI Official Symbol: | CCNI |
| NCBI Official Synonym Symbols: | CYI; CYC1; CCNI1 |
| NCBI Protein Information: | cyclin-I |
| UniProt Protein Name: | Cyclin-I |
| Protein Family: | Cyclin |
| UniProt Gene Name: | CCNI |
| UniProt Entry Name: | CCNI_HUMAN |
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